immunity News and Research

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Gut bacteria toxins: A hidden trigger for Parkinson's disease?

Gut dysfunction and the presence of lipopolysaccharide (LPS) endotoxins contribute to the pathogenesis of Parkinson's disease (PD), leading to neuroinflammation and neurodegeneration. Modulating the gut microbiome and reducing LPS levels may hold potential as treatment strategies for PD.

24 May 2023

Unraveling the Epstein-Barr virus enigma: The puzzling role in multiple sclerosis development

Epstein-Barr virus (EBV) has a significant role in the development of multiple sclerosis (MS), with evidence linking EBV infection to increased MS risk and immune dysregulation. Understanding the mechanisms underlying this connection is crucial for advancing MS therapies and prevention strategies.

24 May 2023

JYNNEOS vaccine shows strong effectiveness against Mpox in New York outbreak

In the recent Morbidity and Mortality Weekly Report (MMWR) published by the Centers for Disease Control and Prevention (CDC), researchers reported on JYNNEOS vaccine effectiveness (VE) against Mpox infections among New York (NY) residents in 2022.

23 May 2023

New vaccine concept could lead to a new generation of vaccines against SARS-CoV-2

Researchers at the University of Basel have developed a new approach for a vaccine against COVID-19.

22 May 2023

Cross-reactivity between Epstein-Barr virus and protein in multiple sclerosis sheds light on disease development

Research uncovers the association between multiple sclerosis (MS) and antibody reactivity to specific amino acids in CRYAB, along with the increased risk when combined with high EBNA1 responses. The study provides evidence of antibody and T cell cross-reactivity between EBNA1 and CRYAB, highlighting the role of EBV adaptive immune responses in MS development.

21 May 2023

Breast milk shields newborns: COVID-19 antibodies and microbiota from vaccinated mothers provide dual defense

Research paper discusses the differences in microbiota between high and low IgA subjects after the second dose of the COVID-19 vaccine. The study found that certain microbial features in breast milk can predict levels of anti-SARS-CoV-2 antibodies in breast milk one week post-second dose.

21 May 2023

Synthetic delivery vector STxB induces mucosal immunity against viral antigens

Research describes the development of a synthetic delivery vector called STxB for mucosal vaccination. It induces mucosal immunity, including resident memory CD8+ T cells and IgA antibodies, against antigens derived from mucosal viruses when administered intranasally in mice.

21 May 2023

Combining generative AI and quantum computing to accelerate drug discovery

Insilico Medicine, a clinical stage generative artificial intelligence (AI)-driven drug discovery company, today announced that it combined two rapidly developing technologies, quantum computing and generative AI, to explore lead candidate discovery in drug development and successfully demonstrated the potential advantages of quantum generative adversarial networks in generative chemistry.

19 May 2023

Genomes of modern humans shaped by admixture events

The course of human history has been marked by complex patterns of migration, isolation, and admixture, the latter a term that refers to gene flow between individuals from different populations.

19 May 2023

Researchers receive $2.3 million to continue development of a new ‘glyco-immune’ checkpoint inhibitor

Researchers from Rice University and Baylor College of Medicine are hoping a first-of-its-kind "glyco-immune" checkpoint inhibitor could be the key to stopping bone cancer metastasis for breast cancer survivors.

19 May 2023

Higher prepregnancy BMI may be associated with shorter duration of breastfeeding

Study claims women with higher body mass index (BMI) breastfeed their infants for shorter durations.

19 May 2023

A novel role for macrophage-activation signaling in orchestrating the recruitment process in response to the SARS-CoV-2 spike protein

Researchers derived peptides from the SARS-CoV-2 spike protein to assess COVID-19-associated inflammatory changes using zebrafish models.

19 May 2023

Both vaccine strain and adjuvant selection are critical elements for improving the breadth of protective immunity against enterovirus D68

Researchers demonstrated the production of cross-clade neutralizing antibodies in response to EV-D68.

19 May 2023

COVID's latest twist: New XBB variant gains strength through recombination, outsmarting immunity and amplifying fusogenicity

Research discusses the emergence of a highly diversified SARS-CoV-2 Omicron subvariant called XBB, which is spreading rapidly around the world. XBB emerged through the recombination of two cocirculating BA.2 lineages, BJ.1 and BM.1.1.1, during the summer of 2022.

18 May 2023

Post-COVID condition varies by variant and vaccination status

Research investigates the post-COVID-19 condition, analyzing its profiles based on viral variants and vaccination status. Understanding these profiles can aid in personalized patient care.

17 May 2023

Novel antibodies target human receptors to neutralize SARS-CoV-2 variants and future sarbecoviruses

Researchers generated six human monoclonal antibodies that prevented infection.

17 May 2023

Updated evidence suggests that masks may be associated with a reduction in risk for SARS-CoV-2 infection

Researchers presented updated evidence of the effectiveness of masks in preventing SARS-CoV-2.

17 May 2023

Are masks effective in the protection against COVID-19?

Researchers discussed the efficacy of masks in preventing coronavirus disease 2019 (COVID-19).

17 May 2023

Cardio boosts immunity: Regular aerobic exercise slashes risk of death from flu and pneumonia

Research examines the association of leisure-time physical activity with mortality from influenza and pneumonia. The study found that aerobic physical activity, even at quantities below the recommended level, may be associated with lower influenza and pneumonia mortality while muscle-strengthening activity demonstrated a J-shaped relationship.

17 May 2023

Study establishes a mechanistic link between obesity and oral cancer immune escape

A team from the University of Michigan Rogel Cancer Center and School of Dentistry, led by Yu Leo Lei, D.D.S., Ph.D., have identified a mechanism in mice for how obesity affects some oral cancers' ability to escape from the immune system.

16 May 2023

immunity News and Research

Gut bacteria toxins: A hidden trigger for Parkinson's disease?

Unraveling the Epstein-Barr virus enigma: The puzzling role in multiple sclerosis development

JYNNEOS vaccine shows strong effectiveness against Mpox in New York outbreak

New vaccine concept could lead to a new generation of vaccines against SARS-CoV-2

Cross-reactivity between Epstein-Barr virus and protein in multiple sclerosis sheds light on disease development

Breast milk shields newborns: COVID-19 antibodies and microbiota from vaccinated mothers provide dual defense

Synthetic delivery vector STxB induces mucosal immunity against viral antigens

Combining generative AI and quantum computing to accelerate drug discovery

Genomes of modern humans shaped by admixture events

Researchers receive $2.3 million to continue development of a new ‘glyco-immune’ checkpoint inhibitor

Higher prepregnancy BMI may be associated with shorter duration of breastfeeding

A novel role for macrophage-activation signaling in orchestrating the recruitment process in response to the SARS-CoV-2 spike protein

Both vaccine strain and adjuvant selection are critical elements for improving the breadth of protective immunity against enterovirus D68

COVID's latest twist: New XBB variant gains strength through recombination, outsmarting immunity and amplifying fusogenicity

Post-COVID condition varies by variant and vaccination status

Novel antibodies target human receptors to neutralize SARS-CoV-2 variants and future sarbecoviruses

Updated evidence suggests that masks may be associated with a reduction in risk for SARS-CoV-2 infection

Are masks effective in the protection against COVID-19?

Cardio boosts immunity: Regular aerobic exercise slashes risk of death from flu and pneumonia

Study establishes a mechanistic link between obesity and oral cancer immune escape

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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