Inflammation News and Research

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Promising new therapy for ulcerative colitis

For people with the chronic disease ulcerative colitis, life can be limited to few social functions and trips away from home.

6 Jan 2006

New model for the origin of rheumatoid arthritis

Rheumatoid arthritis (RA) is one of the most common systemic autoimmune diseases, and one of the least understood. Smoking is the major known environmental risk factor for RA, though little is known about the mechanisms involved.

6 Jan 2006

New pathways linking liver disease to changes in the central nervous system

Liver disease is often associated with "sickness behaviors," such as malaise, listlessness, anorexia, difficulty concentrating, and fatigue. In cholestatic liver diseases (where bile production is impaired) such as primary biliary cirrhosis, fatigue occurs in up to 86 percent of patients.

5 Jan 2006

Treating gum disease may reduce heart problems

The Journal of Dental Research has just published the results of a study showing that treatment of gum disease may reduce the risk of cardiovascular disease.

5 Jan 2006

Brain's endocannabinoids protects neurons from inflammation

Some clinical studies have indicated that marijuana or its active cannabinoid ingredient alleviates symptoms of the inflammatory disease multiple sclerosis (MS).

5 Jan 2006

Clarithromycin reduces recurrent cardiovascular events in patients without periodontitis

Periodontitis, an infection of the gingiva and tooth-supporting tissues, may influence the effectiveness of antibiotics used for the prevention of recurrent cardiovascular events.

5 Jan 2006

SOCS1 silencing could help enhance vaccines against HIV

Researchers from Baylor College of Medicine have shown that switching off a molecule that helps regulate dendritic cells, specialized white blood cells that activate the immune system, could help the host fight HIV infection.

4 Jan 2006

Reduced rates of lung function decline in cystic fibrosis clinical study patients

Although cystic fibrosis patients in clinical trials had more severe illness, worse lung function, a lower weight level and more respiratory infection than non-participants, their involvement in research studies resulted in less lung function decline over a 7-year period.

2 Jan 2006

Childhood infections stunt growth and reduce life expectancy

Records from four European countries show that, on average, survivors of generations with rampant childhood infection - measured by cohort mortality rates at young ages - were shorter and died sooner than counterparts from generations with less childhood disease.

28 Dec 2005

Women suffering lupus OK to take oral contraceptives

Major study of women with either inactive or stable systemic lupus erythematosus (lupus) – a disease in which the body's immune system mistakenly attacks and damages healthy tissues of the skin, joints and internal organs – were able to take oral contraceptives without increased risk of flares, or periods of increased disease activity, that characterize the disease.

22 Dec 2005

Long term air pollution exposure leads to acceleration of atherosclerosis and vascular inflammation

Findings indicate a significant independent association between exposure to long term air pollution and the acceleration of atherosclerosis and vascular inflammation in an animal model.

21 Dec 2005

Kids with specific gene variant more at risk from passive smoking

When U.S. children who possess a variant gene are exposed to second-hand smoke in their homes, they are at a substantially greater risk for developing respiratory illnesses that lead to school absences.

15 Dec 2005

Protein induces dental pulp stem cells into dentin-forming odontoblasts

When dentists examine patients with a damaged tooth that has become infected and abscessed, or filled with tissue-eroding fluid, they typically have two options: Root canal or extraction.

15 Dec 2005

Antibacterial coatings on hip and knee implants cut infection rates

Putting antibacterial coatings on hip and knee implants and biomedical devices such as catheters could cut infection rates following surgery and significantly reduce health care costs and improve quality of life for patients, researchers at the University of South Australia have found.

13 Dec 2005

Nasal flu vaccine just as safe as a jab

According to U.S. government researchers, a new nasal vaccine against influenza, which helps patients avoid the needle, has caused no unexpected side-effects.

7 Dec 2005

Risedronate prevents bone loss and periodontal disease

Drugs that reverse and prevent bone loss due to osteoporosis also significantly ward off periodontal disease, according to a graduate of the Case Western Reserve University School of Dental Medicine who reports in the current Menopause journal article, "Periodontal Assessments of Postmenopausal Women Receiving Risedronate."

7 Dec 2005

New insights into pain mechanisms

Long treated as a side effect, pain is now widely recognized as an integral part of patient care.

7 Dec 2005

Wide variation in the use of laparoscopic surgery for gall bladder removal

There is a wide variation in the use of laparoscopic surgery for gall bladder removal in Hong Kong hospitals, and use of this procedure is more likely at certain hospitals and among younger female patients operated on more recently, according to a study in the Archives of Surgery.

7 Dec 2005

Generation of neoantigenic epitopes after posttranslational modification of Type II collagen by factors present within the inflamed joint

Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation of the joints, which gradually erodes the cartilage and bone.

7 Dec 2005

New study sheds light on role of type II collagen in rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease which gradually erodes cartilage and bone and is characterised by chronic inflammation of the joints.

6 Dec 2005