Inflammation News and Research

RSS

Researchers "should rethink what they are doing" in creating drugs based on a fruit-fly model

The first close-up look at a pro-inflammatory signaling molecule involved in immune response in mammals suggests that researchers "should rethink what they are doing" in creating drugs based on a fruit-fly model, scientists say.

4 Oct 2005

Specific guidelines for treating juvenile idiopathic arthritis

A study published by the Cleveland Clinic and The Hospital for Sick Children (SickKids) provides the medical community for the first time with specific guidelines for treating juvenile idiopathic arthritis (JIA), previously known as juvenile rheumatoid arthritis (JRA), a condition that affects approximately one in every 1,000 children.

4 Oct 2005

Discovery of molecular roots of asthma, arthritis, and multiple sclerosis

The molecular roots of inflammatory and autoimmune diseases such as asthma, arthritis, and multiple sclerosis (MS) have been discovered by a team of researchers led by The University of Texas M. D. Anderson Cancer Center. They say their findings may point to ways to effectively treat these diseases - if not stop them before they start.

4 Oct 2005

Use of the antibiotic amoxicillin during infancy appears to be linked to tooth enamel defects in permanent teeth

Dental fluorosis, a result of exposure to excessive fluoride during enamel formation, is one of the most common developmental enamel defects, according to background information in the article.

4 Oct 2005

Landmark study aims to find genetic link to Alzheimer's disease

More than 500 families affected by Alzheimer's Disease are participating in a landmark study led by Columbia University Medical Center to find a genetic link to the disease. That number will now double to 1,000 under a new $10 million five-year grant from National Institute on Aging.

3 Oct 2005

Research on cartilage erosion and bone abnormalities

While characteristic of osteoarthritis (OA), a degenerative joint disease that affects some 20 million Americans, cartilage erosion and bone abnormalities are also associated with many rare hereditary conditions.

3 Oct 2005

Body's own defenses may cause HIV-related dementia

Publishing in the Sept. 2005 issue of the Journal of Virology, the researchers show that HIV in the temporal lobe mutates at a rate 100 times faster than in other parts of the body, triggering white blood cells to continually swarm to attack the infection. The associated overcrowding and inflammation appear to cause the dementia.

3 Oct 2005

Potential biomarker that could be used to predict who might develop hepatic fibrosis

Two new studies on Hepatitis C (HCV) patients who underwent liver transplants examined a potential biomarker that could be used to predict who might develop hepatic fibrosis, a formation of scar-like tissue that can lead to cirrhosis.

3 Oct 2005

Researchers set out to determine the effectiveness of endomorphin 1, with a painkilling capacity equal to or greater than morphine

Nearly one third of the world's adult population suffers with the pain of arthritis. While NSAIDs and COX-2 inhibitors offer the promise of relief, these drugs also bring the risk of adverse effects, from stomach ulcers to heart attack.

3 Oct 2005

Study shows that high-fat diets correlate to a chronic inflammatory state in the liver,

Mice that were fed diets high in fat and sugar developed immune system abnormalities in their livers, including reduced numbers of natural killer T (NKT) cells. These diet-related changes may contribute to obesity-related liver disease, according to a new study.

3 Oct 2005

Lab-made version of a human protein opens a new research avenue to better understand rheumatoid arthritis

A lab-made version of a human protein alleviates symptoms of both acute and chronic arthritis in mice and could be the basis for a new arthritis drug for people, report scientists from the National Institute of Allergy and Infectious Disease (NIAID), part of the National Institutes of Health (NIH).

3 Oct 2005

Steroids significantly reduce heart damage in children with Kawasaki's disease

When added to standard treatment, steroids significantly reduce the odds of developing heart damage in children with Kawasaki's disease, according to a study in the October issue of Pediatrics. These findings address a gap in knowledge.

3 Oct 2005

Plant-derived compounds appear to block the activity of an enzyme that triggers inflammation in joints

The findings came to light while the researchers were studying the wildly different ways in which cells in human blood vessels and joints respond to pressure gradients generated from liquid moving along their surface, a force called shear stress.

3 Oct 2005

Research may help create drugs to target the molecule-binding pathway, beneficial for treating arthritis and reducing inflammation

3 Oct 2005

Flaviviruses immune system defenses in different ways depending on whether they are transmitted by mosquitoes or ticks

"Flaviviruses exact an enormous toll in terms of illness and death worldwide," notes NIAID Director Anthony S. Fauci, M.D. "Because this is a relatively new field of study, everything we learn about how these viruses operate is significant.

28 Sep 2005

C-reactive protein in atherosclerotic lesions: its origin and pathophysiological significance

New research shows that levels of C-reactive protein (CRP), produced by the liver and not at the lesion site, correlate with the degree of atherosclerosis.

28 Sep 2005

Substance found in cotton plant could help treat psoriasis

A substance found in the cotton plant could help treat the common skin disease psoriasis, according to new research from the Pharmacy School at Sunderland University launched at the British Pharmaceutical Conference in Manchester.

28 Sep 2005

The immune mechanisms of atherosclerosis

Scientists are depicting a novel scheme for atherosclerosis development, suggesting that this pathology might result from an imbalance between pro-inflammatory processes and calming ones.

28 Sep 2005

Treatment of Nonalcoholic Fatty Liver Disease (NAFLD) in children

The Nonalcoholic Steatohepatitis (NASH) Clinical Research Network has launched its second clinical trial to study NASH, a liver disease that resembles alcoholic liver disease but occurs in patients who drink little or no alcohol. The first trial, launched in January of this year, focuses on adults, while the second trial studies the disease in children.

27 Sep 2005

New virus-based gene therapy delivery system to help fight cancer

A Mayo Clinic research team has devised a new virus-based gene therapy delivery system to help fight cancer. Researchers say their findings will help overcome hurdles that have hindered gene therapy cancer treatments.

27 Sep 2005

Inflammation News and Research

Researchers "should rethink what they are doing" in creating drugs based on a fruit-fly model

Specific guidelines for treating juvenile idiopathic arthritis

Discovery of molecular roots of asthma, arthritis, and multiple sclerosis

Use of the antibiotic amoxicillin during infancy appears to be linked to tooth enamel defects in permanent teeth

Landmark study aims to find genetic link to Alzheimer's disease

Research on cartilage erosion and bone abnormalities

Body's own defenses may cause HIV-related dementia

Potential biomarker that could be used to predict who might develop hepatic fibrosis

Researchers set out to determine the effectiveness of endomorphin 1, with a painkilling capacity equal to or greater than morphine

Study shows that high-fat diets correlate to a chronic inflammatory state in the liver,

Lab-made version of a human protein opens a new research avenue to better understand rheumatoid arthritis

Steroids significantly reduce heart damage in children with Kawasaki's disease

Plant-derived compounds appear to block the activity of an enzyme that triggers inflammation in joints

Research may help create drugs to target the molecule-binding pathway, beneficial for treating arthritis and reducing inflammation

Flaviviruses immune system defenses in different ways depending on whether they are transmitted by mosquitoes or ticks

C-reactive protein in atherosclerotic lesions: its origin and pathophysiological significance

Substance found in cotton plant could help treat psoriasis

The immune mechanisms of atherosclerosis

Treatment of Nonalcoholic Fatty Liver Disease (NAFLD) in children

New virus-based gene therapy delivery system to help fight cancer

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News