Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Men exposed to industrial air pollution exhibit sperm mitochondrial DNA deletions

Researchers compare the length spectra of sperm mitochondrial DNA deletions in two seasons with varied air pollution levels.

14 Aug 2022

Crying out for new disease diagnoses

In this interview, we speak to Dr. Fei Liu and Dr. Luke P. Lee about their new iTears platform and how it could help to diagnose disease from tears.

11 Aug 2022

International medical experts aim to use biomarker-based approaches to advance precision medicine

The diagnostics company SphingoTec GmbH (SphingoTec), announces that, during the 4th Scientific Symposium held near Potsdam, Germany, international medical experts discussed the latest developments in diagnostic and therapeutic innovations for advancing precision medicine in critically ill patients.

11 Aug 2022

PET imaging could help measure the pharmacodynamic effects of using STING-activating drugs

Stimulator of interferon genes, or STING, helps regulate immune activation. Thus, drugs that activate STING are being tested as a form of cancer immunotherapy and for treating certain infections.

11 Aug 2022

Blood-based biomarkers can accurately predict a patient's risk of death or disability after TBI

A study funded by the National Institutes of Health found that biomarkers present in the blood on the day of a traumatic brain injury (TBI) can accurately predict a patient's risk of death or severe disability six months later.

10 Aug 2022

Study uncovers new prognostic marker for multiple sclerosis severity

It is essential to assess the severity of multiple sclerosis (MS) in order to choose appropriate therapeutic measures, but this cannot be reliably done using existing methods.

10 Aug 2022

Research identifies unique vulnerabilities in ALT cancers that can serve as novel therapeutic targets

In a study recently published in Cancer Research, a journal of the American Association for Cancer Research, a team of researchers led by C. Patrick Reynolds, M.D., Ph.D., director for the Texas Tech University Health Sciences Center School of Medicine Cancer Center, sought to expand upon his lab's previous research that showed ALT tumors identified by a biomarker known as C-circles share a common biology that confers vulnerabilities to be exploited for cancer therapy.

10 Aug 2022

Abnormal size or functioning in the heart's left atrium may increase dementia risk

Structural or functional abnormalities within the heart's left atrium, with or without symptoms, may increase a person's risk of developing dementia later in life by 35%, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

10 Aug 2022

Overnight EEG studies may help inform care for girls with Rett syndrome

In Rett syndrome, a genetic condition affecting girls almost exclusively, mutations in the MECP2 gene cause a regression of language and motor skills starting at 12 to 18 months of age.

8 Aug 2022

Neoadjuvant chemoimmunotherapy highly effective in patients with resectable stage IIIA NSCLC

In the initial NADIM trial, neoadjuvant chemoimmunotherapy was shown to be highly effective in patients with resectable stage IIIA non-small cell lung cancer.

8 Aug 2022

Boosting vitamin D in individuals with deficiencies likely to reduce chronic inflammation

Inflammation is an essential part of the body's healing process. But when it persists, it can contribute to a wide range of complex diseases including type 2 diabetes, heart disease, and autoimmune diseases.

8 Aug 2022

Vitamin B12, folic acid supplements could potentially halt or reverse advanced form of fatty liver disease

Scientists at Duke-NUS Medical School in Singapore have uncovered a mechanism that leads to an advanced form of fatty liver disease - and it turns out that vitamin B12 and folic acid supplements could reverse this process.

5 Aug 2022

Extracellular vesicle-based surface protein assay likely to lead to a better way to detect early-stage hepatocellular carcinoma

Primary liver cancer, the third-leading cause of cancer-related death worldwide, takes more than 30,000 lives in the United States each year. The high mortality rates can be attributed in part to the fact that a significant portion of the patients are detected at a late stage, when potentially curative treatments are no longer an option. Unfortunately, today's screening methods are not able to routinely provide accurate, early detection.

5 Aug 2022

New easy-to-use test could rapidly diagnose heart attacks and cancers

Imperial researchers have built a new easy-to-use test that could diagnose non-infectious diseases like heart attacks and cancers more quickly.

4 Aug 2022

Researchers assess Alzheimer's disease risk and anti-diabetic drugs

In a new study, researchers assessed the genetic variation among targets of Alzheimer's disease risk and anti-diabetic drugs.

3 Aug 2022

Experts release appropriate use recommendations for Alzheimer’s disease blood biomarkers

Alzheimer’s disease blood biomarkers (BBMs) may revolutionize the diagnosis of Alzheimer’s in the future, but are not yet ready for widespread use, according to a newly-published article by leading international clinicians and researchers convened by the Alzheimer’s Association.

31 Jul 2022

Researchers find adeno-associated virus 2 infection in children with hepatitis of unknown etiology

Researchers investigated the cases of severe hepatitis of unknown etiology in young children who presented to the hospital between 14 March and 4 April 2022 in Scotland.

28 Jul 2022

Epigenetic age acceleration could be used as a biomarker to estimate functional and cognitive aging

A first-of-its-kind study of 1,813 older women suggests that the accelerated biological aging of the body - epigenetic age acceleration specifically - is associated with lower odds of living to be 90 years old and also being physically mobile and having intact mental function.

27 Jul 2022

Study confirms link between Epstein-Barr virus and multiple sclerosis

Researchers investigate the association between Epstein-Barr virus infection and multiple sclerosis.

26 Jul 2022

Specific brain responses to traumatic experiences predict vulnerability to develop PTSD

Results from the largest prospective study of its kind indicate that in the initial days and weeks after experiencing trauma, individuals facing potentially threatening situations who had less activity in their hippocampus – a brain structure critical for forming memories of situations that are dangerous and that are safe – developed more severe posttraumatic stress disorder (PTSD) symptoms.

26 Jul 2022

Biomarker News and Research

Further Reading

Men exposed to industrial air pollution exhibit sperm mitochondrial DNA deletions

Crying out for new disease diagnoses

International medical experts aim to use biomarker-based approaches to advance precision medicine

PET imaging could help measure the pharmacodynamic effects of using STING-activating drugs

Blood-based biomarkers can accurately predict a patient's risk of death or disability after TBI

Study uncovers new prognostic marker for multiple sclerosis severity

Research identifies unique vulnerabilities in ALT cancers that can serve as novel therapeutic targets

Abnormal size or functioning in the heart's left atrium may increase dementia risk

Overnight EEG studies may help inform care for girls with Rett syndrome

Neoadjuvant chemoimmunotherapy highly effective in patients with resectable stage IIIA NSCLC

Boosting vitamin D in individuals with deficiencies likely to reduce chronic inflammation

Vitamin B12, folic acid supplements could potentially halt or reverse advanced form of fatty liver disease

Extracellular vesicle-based surface protein assay likely to lead to a better way to detect early-stage hepatocellular carcinoma

New easy-to-use test could rapidly diagnose heart attacks and cancers

Researchers assess Alzheimer's disease risk and anti-diabetic drugs

Experts release appropriate use recommendations for Alzheimer’s disease blood biomarkers

Researchers find adeno-associated virus 2 infection in children with hepatitis of unknown etiology

Epigenetic age acceleration could be used as a biomarker to estimate functional and cognitive aging

Study confirms link between Epstein-Barr virus and multiple sclerosis

Specific brain responses to traumatic experiences predict vulnerability to develop PTSD

Event guide: 15th World Clinical Biomarkers & CDx Europe eBook

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