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Phages use small RNA to hijack bacterial cells and boost replication

As antibiotic-resistant infections rise and are projected to cause up to 10 million deaths per year by 2050, scientists are looking to bacteriophages, viruses that infect bacteria, as an alternative.

18 Dec 2025

Advances in hemophilia gene therapy bring hope for pediatric patients

In the past three years, gene therapy has reshaped what's possible in hemophilia treatment for patients 18 and older. But a key question remains: How soon will these advances reach children?

18 Dec 2025

Junk' DNA may hold new clues to Alzheimer’s disease

When most of us think of DNA, we have a vague idea it's made up of genes that give us our physical features, our behavioral quirks, and keep our cells and organs running.

18 Dec 2025

Rapid HIV viral load testing shows mixed effects on seeking care

According to the U.S. Centers for Disease Control and Prevention (CDC) and other sources, there are approximately 1.2 million people living with HIV in the United States, and another 1.2 to 2.2 million who are at highest risk for infection and could benefit from the preventive measure known as HIV pre-exposure prophylaxis (PrEP).

18 Dec 2025

Music sessions aid bonding and provide respite in NICUs

Playing soothing live music in intensive care units not only helps parents bond with their baby but also provides a moment's respite from an uncertain and stressful situation, says a senior doctor in the Christmas issue of The BMJ.

18 Dec 2025

Couples-based programs boost heart-healthy behaviors

Research highlights the need for couple-based interventions in heart disease to focus on emotional support and relationship quality for better health outcomes.

18 Dec 2025

Researchers decipher anti-MOG antibody construction, paving way for therapies

MOG Antibody-associated Disease (MOGAD) is a rare autoimmune disease of the central nervous system. The blood of patients contains antibodies against myelin oligodendrocyte glycoprotein (MOG), a protein in the myelin layer that surrounds the neurons in the brain. It is believed that these antibodies contribute to the destruction of this protective layer in the brain.

18 Dec 2025

Many women suffer in silence from treatable pelvic floor conditions

Many women assume pelvic floor health issues are simply their fate—part of having vaginal deliveries, getting older, gaining weight or entering menopause. Perhaps they have watched their mothers and grandmothers live with symptoms, such as urinary incontinence and pain.

17 Dec 2025

Genetic differences can affect the effectiveness of antibody therapies

The genome differs from person to person in thousands of positions. In some cases, this means that proteins have a different building block in certain regions, rendering some antibody-based therapies ineffective, report researchers from the University of Basel, Switzerland.

17 Dec 2025

Novel mRNA therapy rejuvenates immune function in aging mice

Can the weakened immune systems of older individuals be rejuvenated? Researchers from the German Cancer Research Center (DKFZ), the HI-STEM institute, and the Broad Institute have demonstrated that this is possible with an innovative approach.

17 Dec 2025

Nicotine pouch use rises sharply among young men in Great Britain

Use of nicotine pouches has risen substantially in Great Britain over the last five years, particularly among young men, with one in 13 (7.5%) men aged 16 to 24 now using them, according to a new study led by researchers at UCL (University College London).

17 Dec 2025

Mucus-inspired hydrogel resists stomach acid and promotes gastrointestinal healing

The Hong Kong Polytechnic University (PolyU) has developed an acid-resistant "ultra-stable mucus-inspired hydrogel" (UMIH), marking a breakthrough in the field of gastrointestinal medicine.

17 Dec 2025

New clinical trial offers hope for patients with advanced “dry” age-related macular degeneration

Age-related macular degeneration, the leading cause of vision loss and blindness for Americans 65 and older, is a progressive disease affecting central vision.

17 Dec 2025

Lysophosphatidylcholines show gene-dependent effects in early Alzheimer’s disease

A new study presents robust evidence on the role of lysophosphatidylcholines (LPCs) in the onset of Alzheimer's disease. Researchers discovered that LPCs-compounds that transport a variety of healthy fatty acids to the brain-either promote Alzheimer's or protect against it, depending on a person's genetics.

17 Dec 2025

How Traditional Chinese Medicine may reshape the gut microbiome to ease insulin resistance in PCOS

This review synthesizes evidence that gut microbiota dysbiosis contributes to insulin resistance and symptom severity in polycystic ovary syndrome through impaired barrier function, inflammation, and altered microbial metabolites. It evaluates how Traditional Chinese Medicine may modulate these pathways while highlighting major gaps in clinical validation, safety, and standardization.

16 Dec 2025

Global nuclear medicine organizations unite to standardize quantitative PET imaging

Three world-leading nuclear medicine organizations--the SNMMI Clinical Trials Network (SNMMI-CTN), the Australasian Radiopharmaceutical Trials Network (ARTnet), and the European Association of Nuclear Medicine Forschungs GmbH (EARL)--have jointly endorsed a unified PET/CT and PET/MR scanner accreditation framework to standardize and harmonize quantitative PET imaging worldwide.

16 Dec 2025

Combination therapy shows promise to treat a rare, catastrophic pediatric brain cancer

St. Jude Children's Research Hospital scientists identified a promising combination approach to treat a rare, but catastrophic pediatric brain cancer called atypical teratoid rhabdoid tumor (ATRT).

16 Dec 2025

New rapid blood test enables early and accurate diagnosis of ALS

ALS is a debilitating paralytic disease characterized by the death of upper and lower motor neurons. Fortunately, ALS is relatively rare, with an incidence rate of 1.6 per 100,000 adults, resulting in about 30,000 cases in the United States at any one time.

16 Dec 2025

Frog-derived bacteria offer dual-action anticancer effects and high safety

A research team of Prof. Eijiro Miyako at the Japan Advanced Institute of Science and Technology (JAIST) has discovered that the bacterium Ewingella americana, isolated from the intestines of Japanese tree frogs (Dryophytes japonicus), possesses remarkably potent anticancer activity. This groundbreaking research has been published in the international journal Gut Microbes.

16 Dec 2025

Bifunctional biomaterials for postoperative management of osteosarcoma

Osteosarcoma is the most prevalent primary malignant bone tumor in children and adolescents. The current standard treatment involves a combination of chemotherapy and radical surgical resection.

16 Dec 2025