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NIH launches a centralized, secure enclave to store and study COVID-19 patient data

The National Institutes of Health has launched a centralized, secure enclave to store and study vast amounts of medical record data from people diagnosed with coronavirus disease across the country.

15 Jun 2020

Research demonstrates novel pathway regulating the underlying mechanism of NASH

CN Bio, a leading cell culture company that has developed single and multi-organ microphysiological systems that improve the accuracy and efficiency of drug discovery, today announced the publication of co-authored research led by researchers at the University of Cambridge in Nature Metabolism, identifying a novel pathway that regulates the underlying mechanism of Non-Alcoholic Steatohepatitis, potentially a new therapeutic target.

10 Jun 2020

Deep UV LED inactivation of SARS-CoV-2 - fast and effective

The ongoing pandemic has aroused considerable effort to find methods to prevent and control the spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes COVID-19 disease. Rapid inactivation devices would be of great help in this area, to prevent viral transmission through aerosols and contact with infected surfaces.

9 Jun 2020

Study unravels role of a protein in osteoclast generation

Bone-dissolving cells called osteoclasts are derived from a type of immune cells called macrophages. They are necessary for the maintenance and renewal of bones.

9 Jun 2020

Machine learning helps predict clinical forms of drug-induced cardiotoxicity

We announce the publication of a new research paper titled 'Dual transcriptomic and molecular machine learning predicts all major clinical forms of drug cardiotoxicity' in Frontiers in Pharmacology.

9 Jun 2020

Mount Sinai receives award from Microsoft AI for Health to support COVID Informatics Center

The Mount Sinai Health System has received an award from Microsoft AI for Health to support the work of a new data science center dedicated to COVID-19 research.

8 Jun 2020

Experts debate over future Parkinson’s disease trial involving growth factors

Growth factors such as glial cell line-derived neurotrophic factor (GDNF) were initially thought to be exciting new treatments for Parkinson's disease (PD), but trials have been disappointing.

5 Jun 2020

Assessing the integrity of remdesivir clinical trial during COVID-19 pandemic

As acknowledged in the first remdesivir double-blind placebo-controlled clinical trial addressing treatment for COVID-19 recently published in Lancet (Wang, et al., April 29, 2020), a statistician at Rutgers Cancer Institute of New Jersey was called on to guard the integrity of that trial.

4 Jun 2020

Comparing genomes to understand how mutations affect the COVID-19 pandemic

Now, a new study by researchers at the Massachusetts Institute of Technology and the Center for Computational Biology, Flatiron Institute and published online on the bioRxiv preprint server describes how the use of comparative genomics helps to identify protein-coding and non-coding functional genes.

4 Jun 2020

SARS-CoV-2 gene deletions may cause milder infections and increase human-to-human transmission

In their recent paper released on the bioRxiv preprint server, a research group from Spain demonstrated how genome changes and deletions in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) could represent a strategy of natural selection used for lessening the impact of infection in order to increase viral transmission potential.

4 Jun 2020

Exploring the molecular landscape of the aortic niche and beyond

Researchers from the group of Catherine Robin at the Hubrecht Institute characterized the molecular landscape of the aorta that supports the generation of the first Hematopoietic Stem Cells (HSCs) in the embryo.

4 Jun 2020

LMU researchers discover how a microRNA preserves vascular integrity

Ludwig-Maximilian-Universitaet in Munich researchers have discovered a hitherto unknown molecular function of a specific microRNA that preserves integrity of the endothelium and reduces the risk of atherosclerosis.

4 Jun 2020

DFG to establish ten new Collaborative Research Centers

The Deutsche Forschungsgemeinschaft is establishing ten new Collaborative Research Centres to further support top-level research in German universities.

4 Jun 2020

Researchers find link between stroke-related brain blood vessel abnormality and gut bacteria

In a nationwide study, NIH funded researchers found that the presence of abnormal bundles of brittle blood vessels in the brain or spinal cord, called cavernous angiomas (CA), are linked to the composition of a person's gut bacteria.

4 Jun 2020

ISSCR 2020 Virtual Meeting to deliver comprehensive scientific education program

The International Society for Stem Cell Research has transformed its annual scientific meeting into a virtual experience, bringing the global stem cell community together to share knowledge, collaborate, and network.

2 Jun 2020

C-DOCTOR receives $30-million grant from NIDCR for tissue and organ regeneration research

The initiative aims to propel USC forward as the epicenter of tissue and organ regeneration research.

29 May 2020

Examining the envelope protein of SARS-CoV-2

A new study by researchers at the University of Valencia and published on the preprint online server bioRxiv in May 2020 reports the topology of the envelope protein of the virus, which could contribute to a better understanding of how the virus interacts with other cell components and hopefully help to fight the disease better.

28 May 2020

A closer look at TMPRSS2: This could help treat COVID-19

The transmembrane protease serine-type 2 (TMPRSS2) protein plays a key role in COVID-19 infection since it primes the viral spike protein to allow viral entry into the target cell. A new study by researchers at Imperial College London and published on the preprint server bioRxiv in May 2020 describes the protein, which could be an attractive drug target to help manage COVID-19.

28 May 2020

New high-resolution mass spectrometer expands the proven Thermo Scientific Orbitrap platform

A new generation, high resolution mass spectrometer (MS) is designed to give proteomics, metabolomics, biopharmaceutical characterization and small-molecule scientists the analytical performance required for research and high-throughput analyses.

From Thermo Fisher Scientific Inc. 28 May 2020

No-deductible preventive drugs can reduce out-of-pocket costs for diabetic patients

For patients with diabetes - especially those with lower incomes - preventive drug lists (PDLs) of essential medications available with no deductible can reduce out-of-pocket costs while increasing use of important treatments, reports a study in a June supplement to Medical Care.

27 May 2020

Translation News and Research

NIH launches a centralized, secure enclave to store and study COVID-19 patient data

Research demonstrates novel pathway regulating the underlying mechanism of NASH

Deep UV LED inactivation of SARS-CoV-2 - fast and effective

Study unravels role of a protein in osteoclast generation

Machine learning helps predict clinical forms of drug-induced cardiotoxicity

Mount Sinai receives award from Microsoft AI for Health to support COVID Informatics Center

Experts debate over future Parkinson’s disease trial involving growth factors

Assessing the integrity of remdesivir clinical trial during COVID-19 pandemic

Comparing genomes to understand how mutations affect the COVID-19 pandemic

SARS-CoV-2 gene deletions may cause milder infections and increase human-to-human transmission

Exploring the molecular landscape of the aortic niche and beyond

LMU researchers discover how a microRNA preserves vascular integrity

DFG to establish ten new Collaborative Research Centers

Researchers find link between stroke-related brain blood vessel abnormality and gut bacteria

ISSCR 2020 Virtual Meeting to deliver comprehensive scientific education program

C-DOCTOR receives $30-million grant from NIDCR for tissue and organ regeneration research

Examining the envelope protein of SARS-CoV-2

A closer look at TMPRSS2: This could help treat COVID-19

New high-resolution mass spectrometer expands the proven Thermo Scientific Orbitrap platform

No-deductible preventive drugs can reduce out-of-pocket costs for diabetic patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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