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Penn researchers find abnormally shortened telomeres in young DMD patients’ muscle stem cells

Researchers from the Perelman School of Medicine at the University of Pennsylvania have made a discovery about muscular dystrophy disorders that suggest new possibilities for treatment.

7 Sep 2017

Generic drug used to increase blood flow may improve effectiveness of cancer immunotherapy

Cancer immunotherapy drugs only work for a minority of patients, but a generic drug now used to increase blood flow may be able to improve those odds, a study by Columbia University Medical Center researchers suggests.

7 Sep 2017

Research shows new method for rapidly producing antimalarial drug at industrial scale

Compared to smallpox or typhoid, malaria is proving one of the most challenging human diseases to eradicate - and so remains a real and constant danger to nearly half the world's population.

7 Sep 2017

New human stem cell model could pave way for macular degeneration research

Macular degeneration is the leading cause of vision loss in older adults, but scientists have long struggled to study and replicate key elements of the disease in the lab.

7 Sep 2017

Researchers define how cancer drug works in cells, mice and man

Science is very good at determining how drugs work in experimental models. New research out of Dartmouth's Norris Cotton Cancer Center led by Alan Eastman, PhD, helps to bridge the gap when it comes to ensuring that drugs work by the same mechanism in human patients.

7 Sep 2017

ASMR soundscape aids in longer, healthier sleep

AXA PPP healthcare has collaborated with ASMRtist WhispersRed in order to remaster its very own track, creating a new night sound that can induce relaxation, aiding in longer sleep duration and healthier sleep patterns.

7 Sep 2017

New microfluidic device offers insights on cancer metastasis

As cancer grows, it evolves. Individual cells become more aggressive and break away to flow through the body and spread to distant areas.

7 Sep 2017

Study identifies genes that regulate gestational length and likelihood of preterm delivery

The genes that regulate gestational length and the likelihood of preterm delivery, have been identified in a study involving more than 50,000 women. An article in the New England Journal of Medicine (NEJM) describes the scientific breakthrough that can lead to improved health and survival among children.

7 Sep 2017

Study describes link between key melanoma signaling pathway and novel class of drugs

Results of a study by The Wistar Institute have described a correlation between a key melanoma signaling pathway and a novel class of drugs being tested in the clinic as adjuvant therapy for advanced melanoma, providing useful information for a more effective use of this type of treatment.

7 Sep 2017

Novel compounds found to be highly effective in preventing transmission of malaria parasites

Significant headway has been made in controlling malaria. However, two vexing problems remain: currently available treatments are unable to block transmission of the parasite that causes the disease, and the parasite often becomes resistant to drugs.

7 Sep 2017

Natural compound produced by honeybees could become basis for new antibiotics

An antimicrobial compound made by honeybees could become the basis for new antibiotics, according to new research at the University of Illinois at Chicago.

7 Sep 2017

Exploration of human genetics reveals new targets to combat heart disease

Again and again, it's the rare among humans that help the rest of us. The exploration of human genetics is revealing new targets to combat heart disease among atypical variants. Mutations in genes that play a role in heart health are the inspiration for a cluster of new heart drugs.

7 Sep 2017

Breakthrough study could lead to diagnostic tools and better treatments for chronic bronchitis

When a patient arrives at a doctor's office with a persistent cough and the sensation of gunk building up in the lungs, the doctor's thought process is essentially the same as it would have been decades ago. There has been no understanding of the affected biological pathways causing the gunk buildup in the lung, nor has there been a diagnostic test for chronic bronchitis.

7 Sep 2017

Women experience concussion differently compared to their male counterparts

Scientists have known for more than a decade that female athletes sustain concussions at a higher rate than males when playing sports with similar rules, such as soccer, basketball and baseball/softball. Females also tend to report more symptoms - and more severe ones--and may also take longer to recover from brain injuries than their male counterparts.

6 Sep 2017

Researchers study two new drugs to find alternative treatment for men with erectile dysfunction

Close to 70 percent of men with erectile dysfunction (ED) respond to the ED drug sildenafil. However, only about 50 percent of men with diabetes- a population commonly affected by ED- achieve positive results with sildenafil.

6 Sep 2017

Parkinson’s disease detection by simple smell or drawing tests find two parallel studies

According to a latest study from the Michigan State University, a simple “scratch and sniff” test could be enough to predict Parkinson’s disease before it starts is debilitating curse.

6 Sep 2017

Controlling zinc transporter levels could be effective plan to combat pancreatic cancer, other diseases

When trace elements rise to toxic levels, bad things happen. Patients suffering from Alzheimer's and Parkinson's disease harbor significantly higher levels of zinc and iron in their brains than healthy patients.

6 Sep 2017

Molecular map shows novel way to stop dangerous bioweapon

During World War II, the Soviet Red Army was forced to move their biological warfare operations out of the path of advancing Nazi troops. Among the dangerous cargo were vials of Francisella tularensis, the organism that causes tularemia and one of the world's most infectious pathogens.

6 Sep 2017

Substances in coffee could help quash risk of developing diabetes

In recent years, researchers have identified substances in coffee that could help quash the risk of developing Type 2 diabetes. But few of these have been tested in animals. Now in study appearing in ACS' Journal of Natural Products, scientists report that one of these previously untested compounds appears to improve cell function and insulin sensitivity in laboratory mice.

6 Sep 2017

Researcher develops bone marrow models to study hematological and musculoskeletal diseases

For her research on the development of hematological and musculoskeletal disorders, Dr. Cornelia Lee-Thedieck, scientist at Karlsruhe Institute of Technology, is awarded an ERC Starting Grant: The European Research Council decided to fund her project "bloodANDbone" with EUR 1.5 million for five years. At KIT's Institute of Functional Interfaces, Lee-Thedieck develops models of the human bone marrow to study the regeneration of blood and bone by stem cells and how this regeneration is disturbed in diseases like leukemia or bone metastases.

6 Sep 2017

Drugs News and Research

Penn researchers find abnormally shortened telomeres in young DMD patients’ muscle stem cells

Generic drug used to increase blood flow may improve effectiveness of cancer immunotherapy

Research shows new method for rapidly producing antimalarial drug at industrial scale

New human stem cell model could pave way for macular degeneration research

Researchers define how cancer drug works in cells, mice and man

ASMR soundscape aids in longer, healthier sleep

New microfluidic device offers insights on cancer metastasis

Study identifies genes that regulate gestational length and likelihood of preterm delivery

Study describes link between key melanoma signaling pathway and novel class of drugs

Novel compounds found to be highly effective in preventing transmission of malaria parasites

Natural compound produced by honeybees could become basis for new antibiotics

Exploration of human genetics reveals new targets to combat heart disease

Breakthrough study could lead to diagnostic tools and better treatments for chronic bronchitis

Women experience concussion differently compared to their male counterparts

Researchers study two new drugs to find alternative treatment for men with erectile dysfunction

Parkinson’s disease detection by simple smell or drawing tests find two parallel studies

Controlling zinc transporter levels could be effective plan to combat pancreatic cancer, other diseases

Molecular map shows novel way to stop dangerous bioweapon

Substances in coffee could help quash risk of developing diabetes

Researcher develops bone marrow models to study hematological and musculoskeletal diseases

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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