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Scientists develop bone marrow-on-a-chip to test effects of new drugs, toxic agents on bone marrow

The latest organ-on-a-chip from Harvard's Wyss Institute for Biologically Inspired Engineering reproduces the structure, functions and cellular make-up of bone marrow, a complex tissue that until now could only be studied intact in living animals, Institute researchers report in the May 4, 2014, online issue of Nature Methods.

6 May 2014

MEI Pharma begins ME-344 Phase Ib clinical study in patients with solid tumors

MEI Pharma, Inc., an oncology company focused on the clinical development of novel therapies for cancer, announced today that the first patient has been dosed in a Phase Ib clinical study of its investigational mitochondrial inhibitor drug candidate ME-344 in combination with Hycamtin (topotecan) in patients with solid tumors, including small cell lung and ovarian cancers.

6 May 2014

Physiology researcher receives grant to study effects of plastics on cardiovascular system

Nikki Posnack, Ph.D., a post-doctoral pharmacology and physiology researcher at the George Washington University School of Medicine and Health Sciences (SMHS), received a $209,926 grant from the National Institute of Environmental Health Sciences to study plastics and their potential human health risks, particularly in the cardiovascular system.

6 May 2014

Researchers aim to take confusion out of food choices for people with type 2 diabetes

Aiming to take the confusion out of food choices for people diagnosed with type 2 diabetes is the aim of new research at Griffith University.

5 May 2014

Supermarket access key ingredient in obesity programs

Living close to a supermarket appears to be a key factor in the success of interventions to help obese children eat better and improve their weight, according to a study to be presented Saturday, May 3, at the Pediatric Academic Societies (PAS) annual meeting in Vancouver, British Columbia, Canada.

5 May 2014

Infants heavily breastfeed after age of 6 months are not getting sufficient dietary diversity

Approximately three of every four Cincinnati infants heavily breastfeed after the age of six months is not obtaining the level of dietary diversity recommended by the World Health Organization, according to a new Cincinnati Children's Hospital Medical Center study.

5 May 2014

FDA grants Orphan Drug Designation to Advaxis' ADXS-HPV for treatment of invasive cervical cancer

Advaxis, Inc., a leader in developing cancer immunotherapies, announced today that it has been granted Orphan Drug Designation from the U.S. Food and Drug Administration Office of Orphan Products Development (OOPD) for ADXS-HPV, its lead immunotherapy drug candidate, for the treatment of Stage II-IV invasive cervical cancer.

2 May 2014

Public health specialists call on David Cameron to act on hunger crisis in the UK

Public health specialists are today calling on the Prime Minister David Cameron to take action on nutrition and hunger in the UK.

2 May 2014

Ruthigen files IND Application to FDA for lead drug candidate RUT58-60

Ruthigen, Inc., a biopharmaceutical company focused on the discovery, development and commercialization of novel therapeutics designed to prevent and treat infection in invasive applications, today announced that the Company has submitted an Investigational New Drug (IND) Application to the U.S. Food and Drug Administration for its lead drug candidate RUT58-60.

2 May 2014

Acorda gets FDA Complete Response Letter for PLUMIAZ Nasal Spray NDA

Acorda Therapeutics, Inc. today announced that the U.S. Food and Drug Administration has issued a Complete Response Letter (CRL) for the New Drug Application (NDA) for PLUMIAZ (diazepam) Nasal Spray for the treatment of people with epilepsy who experience cluster seizures.

2 May 2014

Study suggests reasons for disparities in obesity rates between African-American and white women

A new study suggests the reasons for disparities in obesity rates between African-American and white women are far more complex than the usual go-to culprits of socioeconomics, fruit and vegetable intake, and exercise.

2 May 2014

FDA approves Parion’s investigational new drug application for treatment of dry eye disease

Parion Sciences, a company dedicated to the development of novel treatments for ocular and pulmonary diseases, announced today that it has received acceptance from the U.S. Food and Drug Administration (FDA) of its Investigational New Drug (IND) application for P-321 Ophthalmic Solution for the treatment of dry eye disease.

2 May 2014

3 rules of thumb to reduce childhood obesity

Kristopher Kaliebe, MD, Clinical Assistant Professor of Psychiatry at the LSU Health Sciences Center New Orleans School of Medicine, offers parents and caregivers three simple family-oriented goals to overcome the complex problem of childhood obesity and related mental disorders.

2 May 2014

Researchers find two types of neurons that enable spinal cord to control skilled forelimb movement

Researchers have identified two types of neurons that enable the spinal cord to control skilled forelimb movement. The first is a group of excitatory interneurons that are needed to make accurate and precise movements; the second is a group of inhibitory interneurons necessary for achieving smooth movement of the limbs.

2 May 2014

Scientists develop experimental drug that prolongs lifespan in mouse model of accelerated aging

Northwestern Medicine- scientists have newly identified a protein's key role in cell and physiological aging and have developed - in collaboration with Tohoku University in Japan -- an experimental drug that inhibits the protein's effect and prolonged the lifespan in a mouse model of accelerated aging.

2 May 2014

UT Southwestern docs receive grants for innovative studies on lung cancer pathways, drug therapy

Two UT Southwestern doctors have received more than a half-million dollars in grants from the Department of Defense for innovative studies on lung cancer pathways and to test the effectiveness of a potentially less expensive drug therapy.

2 May 2014

Biotech to the rescue

MIT professor Ram Sasisekharan's three biotech companies — Momenta Pharmaceuticals, Cerulean Pharma, and Visterra — share a similar goal.

1 May 2014

Noninvasive technique detects prostate cancer using an electronic nose

We may soon be able to make easy and early diagnoses of prostate cancer by smell. Investigators in Finland have established that a novel noninvasive technique can detect prostate cancer using an electronic nose. In a proof of principle study, the eNose successfully discriminated between prostate cancer and benign prostatic hyperplasia (BPH) by "sniffing" urine headspace (the space directly above the urine sample). Results using the eNose are comparable to testing prostate specific antigen (PSA), reports the Journal of Urology.

1 May 2014

Frozen meals closer to meeting Dietary Guidelines than quick service restaurant meals

New analysis of data from the 2003-2010 What We Eat In America (WWEIA) National Health and Nutrition Examination Survey (NHANES), a program of the Centers for Disease Control and Prevention (CDC), indicates that consumers of frozen meals (1) compared to consumers of quick service restaurant (QSR) meals (2) had lower calorie intakes and better Healthy Eating Index (HEI) score. In fact, the analysis revealed that those who consumed frozen meals consumed 253 fewer calories than those who consumed a quick service restaurant meal.

1 May 2014

Teva announces positive results from pivotal Phase III study of hydrocodone bitartrate extended-release tablets

Teva Pharmaceutical Industries Ltd. today announced positive results from a pivotal Phase III study of hydrocodone bitartrate extended-release tablets designed with Teva's proprietary technology providing potential abuse-deterrent properties (CEP-33237).

30 Apr 2014

Food News and Research

Scientists develop bone marrow-on-a-chip to test effects of new drugs, toxic agents on bone marrow

MEI Pharma begins ME-344 Phase Ib clinical study in patients with solid tumors

Physiology researcher receives grant to study effects of plastics on cardiovascular system

Researchers aim to take confusion out of food choices for people with type 2 diabetes

Supermarket access key ingredient in obesity programs

Infants heavily breastfeed after age of 6 months are not getting sufficient dietary diversity

FDA grants Orphan Drug Designation to Advaxis' ADXS-HPV for treatment of invasive cervical cancer

Public health specialists call on David Cameron to act on hunger crisis in the UK

Ruthigen files IND Application to FDA for lead drug candidate RUT58-60

Acorda gets FDA Complete Response Letter for PLUMIAZ Nasal Spray NDA

Study suggests reasons for disparities in obesity rates between African-American and white women

FDA approves Parion’s investigational new drug application for treatment of dry eye disease

3 rules of thumb to reduce childhood obesity

Researchers find two types of neurons that enable spinal cord to control skilled forelimb movement

Scientists develop experimental drug that prolongs lifespan in mouse model of accelerated aging

UT Southwestern docs receive grants for innovative studies on lung cancer pathways, drug therapy

Biotech to the rescue

Noninvasive technique detects prostate cancer using an electronic nose

Frozen meals closer to meeting Dietary Guidelines than quick service restaurant meals

Teva announces positive results from pivotal Phase III study of hydrocodone bitartrate extended-release tablets

Understanding cultivated meat and its global potential eBook

Managing vibration in IVF laboratories

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

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