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Gene mutation protecting against malaria linked to prostate cancer incidence in African-American men

Research from the University of Cincinnati College of Medicine suggests that the 60 percent greater incidence of prostate cancer among African-American men is related to a gene mutation developed generations ago in West Africa as nature's way of providing protection from the malaria infection endemic in that part of the world.

4 Apr 2005

Certain combinations of genes increase the risk of developing cervical cancer

Certain combinations of genes that encode receptors on innate immune cells increase the risk of developing cervical cancer, according to a study by Mary Carrington and colleagues in the April 4 issue of The Journal of Experimental Medicine.

4 Apr 2005

Natural killer cells could lead to new Hepatitis treatments

Researchers have discovered that natural killer T (NKT) cells, the immune system's sentinels, patrol the labyrinthine blood vessels of the liver for invaders or signs of tissue damage and demonstrate a dogged behavior not seen before in other T cells.

4 Apr 2005

Chronic inflammation caused by too little stomach acid leads to gastric cancer

When it comes to gastric cancer, too little stomach acid can be just as dangerous as too much, according to scientists at the University of Michigan Medical School. Both extremes create inflammatory changes in the stomach lining and a condition called chronic atrophic gastritis, which over time often leads to cancer.

4 Apr 2005

Why smokers lung is resistant to steroid treatment

UK researchers think they are close to finding the first effective treatment to fight one of the biggest killer diseases in the UK. Professor Peter Barnes will present the work at the British Endocrine Societies 2005 meeting in Harrogate.

4 Apr 2005

New ion channel drug targets to emerge in pharmaceutical discovery

The identification and structural determination of channel proteins, and their validation as therapeutic targets using high throughput cell based and multiplexed screening technologies, have furnished an increase role for ion channel targets in the drug discovery and development pipelines in the pharmaceutical and biotechnology industries.

4 Apr 2005

Blue light kills gum disease

Scientists at The Forsyth Institute have found that blue light can be used to selectively suppress certain bacteria commonly associated with destructive gum disease.

3 Apr 2005

New trial for treatment of liver disease

The Nonalcoholic Steatohepatitis (NASH) Clinical Research Network is launching its first two clinical trials for the study of NASH, a liver disease that resembles alcoholic liver disease but occurs in patients who drink little or no alcohol.

3 Apr 2005

Airway inflammation boosts infarction damage

Epidemiological studies show that the incidence of cardiovascular disease (CVD) complications are increased in long standing cases of asthma. Historically, the complications are often attributed to the chronic drug therapy used to treat asthma.

3 Apr 2005

Asthma patients' immune systems respond differently with allergies

Researchers from the University of Chihuahua in Mexico report that immune systems of patients with asthma responded differently to a common laboratory challenge, depending on whether their white blood cells had been obtained during a time when they were suffering from common season allergic rhinitis or when they were free of such allergic symptoms.

3 Apr 2005

First UK cases of previously rare disease reported in gay men

A previously rare disease has been reported for the first time in the UK, Lymphograunuloma venereum (LGV) is a genital/anogenital bacterial infection caused by a particularly invasive strain of Chlamydia trachomatis.

3 Apr 2005

CDC experts sent to Angola to help with Marburg epidemic

In an effort to control the Marburg virus outbreak in Angola, Health officials from the Centers for Disease Control and Prevention in Atlanta will assist the World Health Organization by going to Angola to help with outbreak investigation, infection control and laboratory diagnosis of the disease.

30 Mar 2005

Hemodialysis causes antioxidant loss leading to long-term complications

An article published in Hemodialysis International discusses the role of oxidative stress (OS) in dialysis patients, an imbalance which can result in long-term health problems. Potential therapeutic options to restore balance in patients are also reviewed.

30 Mar 2005

Vaccine prevents deadly pneumonia in African children

Global health leaders today presented new research showing that vaccinating infants against Streptococcus pneumoniae -- a bacterium that causes deadly pneumonia, meningitis and sepsis -- could substantially reduce death and serious illness among children in the developing world. If used widely, a pneumococcal conjugate vaccine could prevent hundreds of thousands of child deaths each year.

28 Mar 2005

Body fat may promote inflammation

Why does extra fat around the waist increase the risk of heart disease? A new study by Wake Forest University Baptist Medical Center researchers and colleagues suggests that inflammation may be the key.

28 Mar 2005

Vegetarians who don't cook their food have abnormally low bone mass

Vegetarians who don't cook their food have abnormally low bone mass, usually a sign of osteoporosis and increased fracture risk. But a research team at Washington University School of Medicine in St. Louis also found that raw food vegetarians have other biological markers indicating their bones, although light in weight, may be healthy.

28 Mar 2005

Hope of new treatments for liver damage

There is currently no cure for liver cirrhosis and a patient's only hope of survival is to receive a liver transplant.

28 Mar 2005

Vaccine against pneumonia and invasive pneumococcal disease shows promise

A vaccine against pneumonia and invasive pneumococcal disease, a severe form of bacterial infection, can substantially reduce hospital admissions and improve the survival of children in developing countries, concludes a trial published in this week’s issue of The Lancet.

28 Mar 2005

Miami baby possibly USA's 1st case of West Nile virus

West Nile Virus is a flavivirus commonly found in Africa, West Asia, and the Middle East and is related to the St. Louis encephalitis virus found in the United States. Preliminary tests suggest a 14-month-old baby hospitalized in Miami may be the nation's first case of West Nile virus this year.

22 Mar 2005

No serious adverse events found with next-generation smallpox vaccine

Interim data from a phase I/II clinical trial of a next-generation vaccine for smallpox suggest that the vaccine may provide immunity and thus far the trial has been without any serious adverse events.

22 Mar 2005