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Protein from gut worms accelerates skin regeneration and reduces scarring

Researchers at Rutgers University in New Jersey have discovered that a protein produced by parasitic worms in the gut enhances wound healing in mice.

23 Aug 2024

Unique strain of probiotic bacteria shows potential in combating inflammatory diseases

23 Aug 2024

AI advances drug discovery for mental health disorders with new receptor models

Artificial intelligence (AI) can help identify molecules that could serve as new drugs for mental health disorders.

23 Aug 2024

Maternal gut bacteria linked to changes in fetal brain metabolism

The impact of Bifidobacterium breve's presence in the maternal gut during pregnancy on fetal brain metabolism.

23 Aug 2024

New analytical method for identifying cancer cell targets

What are the characteristics of a cancer cell that are recognized by the immune system? Knowledge of the potential target structures for the immune cells is a basic prerequisite for the development of personalized cancer immunotherapies. Scientists from the German Cancer Research Center (DKFZ) and the NCT Heidelberg are publishing a highly sensitive method based on mass spectroscopy to identify such tumor-specific "neoepitopes". The analytical method is designed to detect these low-abundance protein fragments and requires minimal amounts of sample material.

23 Aug 2024

Exploring the impact of thyroid hormone on brain function

Thyroid hormone plays a key role in regulating a range of physiologic functions, including metabolism, temperature, heart rate, and growth. It accomplishes this impressive array of activities by interacting with almost every organ system in the body. Yet despite a long history of research on how thyroid hormone influences different organs, its effects on arguably the most crucial organ - the brain - have remained shrouded in mystery.

23 Aug 2024

Probiotic offers protection against intestinal damage

There is a critical unmet need to help tighten and maintain a healthy intestinal barrier and treat a leaky gut. Researchers have now found that a unique strain of probiotic bacteria, Bifidobacterium bifidum BB1, enhances intestinal barrier function and protects against penetration of bacteria and various harmful agents in the intestine. The findings, detailed in an article in The American Journal of Pathology, published by Elsevier, can help advance the development of novel, targeted, naturally occurring probiotic therapy for patients with inflammatory bowel disease (IBD) and other inflammatory diseases, such as fatty liver disease or alcoholic liver disease, that are associated with a leaky or disordered intestinal barrier.

23 Aug 2024

Anti-obesity medication may help to prevent heart attacks and other major cardiac events

The anti-obesity medication semaglutide may help to prevent heart attacks and other major adverse cardiac events among overweight people who have cardiovascular disease, whether or not they also have heart failure, according to a new study led by UCL's Professor John Deanfield.

22 Aug 2024

New insights into macrophages' role in MASH and liver fibrosis

Formerly known as nonalcoholic steatohepatitis, metabolic dysfunction-associated steatohepatitis (MASH) is an inflammatory disease characterized by liver scarring or fibrosis that progressively impairs liver function.

22 Aug 2024

Investigational drug reduces hot flashes associated with menopause

The investigational drug elinzanetant significantly reduces the frequency and severity of hot flashes associated with menopause while improving women's quality of life, new UVA Health research published in the prestigious Journal of the American Medical Association shows.

22 Aug 2024

Robotic gait training improves mobility in patients with spinal and bulbar muscular atrophy

Spinal and bulbar muscular atrophy (SBMA) is a rare X-linked neuromuscular disorder that results from an abnormal expansion of gene sequences in the androgen receptor gene.

22 Aug 2024

Potential antitumoral effects of Manuka honey in breast cancer models

Researchers evaluated the antitumor activity of Manuka honey on human breast cancer cells and its underlying molecular mechanisms in both in vitro and in vivo preclinical models.

22 Aug 2024

Study links fine particulate matter exposure to increased risk of gestational diabetes

Researchers assesses the relationship between exposure to fine particulate matter and the risk of gestational diabetes mellitus.

22 Aug 2024

Gut molecule blocks fat burning during fasting in C. elegans

In a struggle that probably sounds familiar to dieters everywhere, the less a Caenorhabditis elegans (C. elegans) worm eats, the more slowly it loses fat.

21 Aug 2024

Breakthrough compound targets appetite and tau protein in obesity and Alzheimer's

Scientists on the team of Dr Lenka Maletínská have developed a promising new compound derived from one of the peptides naturally occurring in the brain.

21 Aug 2024

Hair follicles use unique sensor system to clean up dead cells

Billions of our cells die every day to make way for the growth of new ones. Most of these goners are cleaned up by phagocytes - mobile immune cells that migrate where needed to engulf problematic substances.

21 Aug 2024

MolCompass: A breakthrough in identifying weak areas of chemical prediction models

In recent years, machine learning models have become increasingly popular for risk assessment of chemical compounds.

21 Aug 2024

Study finds potential for antidiabetic drugs to modify osteoarthritis risk

Whether antidiabetic medications could potentially be used as disease-modifying osteoarthritis drugs or DMOADs for the therapeutic management of osteoarthritis.

21 Aug 2024

Gut microbiome discovery paves the way for new heart failure treatments

Cleveland Clinic researchers have made a significant discovery about how the gut microbiome interacts with cells to cause cardiovascular disease.

20 Aug 2024

Advances in precision medicine enhance cancer immunotherapy

The field of precision medicine, especially in the context of cancer immunotherapy, has seen significant advancements in recent years.

20 Aug 2024

Receptor News and Research

Protein from gut worms accelerates skin regeneration and reduces scarring

Unique strain of probiotic bacteria shows potential in combating inflammatory diseases

AI advances drug discovery for mental health disorders with new receptor models

Maternal gut bacteria linked to changes in fetal brain metabolism

New analytical method for identifying cancer cell targets

Exploring the impact of thyroid hormone on brain function

Probiotic offers protection against intestinal damage

Anti-obesity medication may help to prevent heart attacks and other major cardiac events

New insights into macrophages' role in MASH and liver fibrosis

Investigational drug reduces hot flashes associated with menopause

Robotic gait training improves mobility in patients with spinal and bulbar muscular atrophy

Potential antitumoral effects of Manuka honey in breast cancer models

Study links fine particulate matter exposure to increased risk of gestational diabetes

Gut molecule blocks fat burning during fasting in C. elegans

Breakthrough compound targets appetite and tau protein in obesity and Alzheimer's

Hair follicles use unique sensor system to clean up dead cells

MolCompass: A breakthrough in identifying weak areas of chemical prediction models

Study finds potential for antidiabetic drugs to modify osteoarthritis risk

Gut microbiome discovery paves the way for new heart failure treatments

Advances in precision medicine enhance cancer immunotherapy

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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