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Diet influenced by genetics

The relative amount of protein, carbohydrate, and fat that people choose to eat may be influenced by genetics, according to new research.

8 Jun 2007

New target for the Fragile X mental retardation protein

Researchers in the Department of Obstetrics, Gynecology & Reproductive Sciences at Yale School of Medicine have identified a new regulatory target for the Fragile X mental retardation protein (FMRP), laying the groundwork for possible new treatments for Fragile X syndrome(FXS), the leading inherited form of mental retardation.

8 Jun 2007

Blocking the action of beta1-integrin to treat cancer

Targeting the function of a protein known as beta1-integrin might represent a novel approach to cancer treatment, according to a paper published online in the EMBO Journal.

8 Jun 2007

Aging stem cells in mice may hold answers to diseases of the aged

As stem cells in the blood grow older, genetic mutations accumulate that could be at the root of blood diseases that strike people as they age, according to work done in mice by researchers at the Stanford University School of Medicine.

8 Jun 2007

Parents using Ritalin to get children through exams and divorce

Reports in the Chinese media say some parents are prepared to dose their offspring with powerful drugs to help them through exams.

5 Jun 2007

Researchers find stem cells in colorectal tumors

Researchers at the Stanford University School of Medicine have identified the cancer stem cells that propagate tumors in colon and rectal cancer, a discovery that could lead to improved treatment of this deadly cancer.

5 Jun 2007

Genetic variations may help explain why some men with depression develop suicidal thoughts

Although most patients with depression respond favorably to antidepressant medications, a very small subgroup may experience worse symptoms after beginning treatment, according to background information in the article.

5 Jun 2007

Blocking stress protein decreases Alzheimer's peptide

Scientists revealed in November 2006 that stress increases production in mice of a brain peptide critical to Alzheimer's disease.

5 Jun 2007

breakthrough in the treatment of idiopathic pulmonary haemosiderosis

Researchers at Queen Mary University London and the University of Leicester and have announced a potential breakthrough in the treatment of a rare but devastating medical condition that can affect children and young people.

5 Jun 2007

What causes Alzheimer's disease?

Researchers tied the accumulation of the toxic brain protein beta-amyloid to Alzheimer's disease, according to a study reported at the 54th Annual Meeting of SNM, the world's largest society for molecular imaging and nuclear medicine professionals.

5 Jun 2007

How and why weight-reducing surgery sometimes cures diabetes

95% of morbidly obese people – those with a Body Mass Index of over 40 – have Type 2 diabetes, sometimes known as maturity-onset diabetes.

5 Jun 2007

VEGF Trap (aflibercept) shows activity in patients with advanced ovarian cancer

Preliminary results of a randomized, international Phase II trial of VEGF Trap (aflibercept) show activity in patients with recurrent epithelial ovarian cancer (EOC) who had received three or four prior chemotherapy regimens and had become resistant to platinum-based chemotherapy agents.

5 Jun 2007

Vorinostat shows anti-cancer activity in recurrent gliomas

North Central Cancer Treatment Group (NCCTG) researchers, based at Mayo Clinic in Rochester, Minn., report that a novel application of the drug vorinostat shows activity in patients with recurrent glioblastoma multiforme.

5 Jun 2007

Study finds lymphoma drug effective over long term

Eight years after being treated with a new drug for non-Hodgkin's lymphoma, 86 percent of patients were still alive and half had not had a relapse of their disease, according to researchers from the University of Michigan Comprehensive Cancer Center.

5 Jun 2007

Protein S-100 linked to melanoma recurrence

Higher levels of a protein called S-100 in patients with melanoma may correlate with a higher risk of having the disease return, say researchers at the University of Pittsburgh Cancer Institute (UPCI), who presented their findings today at the annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago.

5 Jun 2007

Gene responsible for Leber Congenital Amaurosis

A MUHC-led study identifies a gene responsible for Leber Congenital Amaurosis (LCA), the most common cause of congenital blindness in infants and small children.

5 Jun 2007

Herceptin does not increase heart failure in patients long-term

Risk of congestive heart failure in women treated with trastuzumab (Herceptin) and combination chemotherapy for early-stage breast cancer did not increase over time according to a five-year follow-up of National Surgical Adjuvant Breast and Bowel Project (NSABP) trial B-31, presented at the annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago.

5 Jun 2007

Gene therapy delivery of nerve growth factors reverses erectile dysfunction in mice

Rats with erectile dysfunction, or ED, that were injected with a gene therapy vector containing either of two nerve growth factors were able to regain normal function after four weeks, according to a study conducted by University of Pittsburgh School of Medicine researchers.

5 Jun 2007

Stroke victims could be more vulnerable to Alzheimer's

University of Leeds scientists have shown how stroke victims could be more vulnerable to Alzheimer's disease – years or even decades after making a full recovery.

5 Jun 2007

Dasatinib shows promise as first treatment for chronic myelogenous leukemia

An established second-line drug for chronic myelogenous leukemia has high response rates when given to newly diagnosed patients as their first therapy for the disease, according to early results from a Phase II clinical trial at The University of Texas M. D. Anderson Cancer Center.

5 Jun 2007