Chromosome 4 News and Research

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Humans normally have 46 chromosomes in each cell, divided into 23 pairs. Two copies of chromosome 4, one copy inherited from each parent, form one of the pairs. Chromosome 4 spans more than 191 million DNA building blocks (base pairs) and represents more than 6 percent of the total DNA in cells.

Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 4 likely contains between 1,300 and 1,600 genes.

Genes on chromosome 4 are among the estimated 20,000 to 25,000 total genes in the human genome.
Cancer genomes: Distinguishing between 'driver' and 'passenger' mutations

Cancer genomes: Distinguishing between 'driver' and 'passenger' mutations

Most genetic abnormalities shared across multiple cancers

Most genetic abnormalities shared across multiple cancers

Study analyzes genome and exome sequence data from hunter-gatherer participants of South Africa

Study analyzes genome and exome sequence data from hunter-gatherer participants of South Africa

Novartis' Tasigna capsules granted priority review by FDA for treatment of adult patients with Ph+ CML

Novartis' Tasigna capsules granted priority review by FDA for treatment of adult patients with Ph+ CML

Johns Hopkins Kimmel Cancer Center scientists develop genome-based blood tests for cancer

Johns Hopkins Kimmel Cancer Center scientists develop genome-based blood tests for cancer

Researchers have traced protein that stops cells from becoming cancerous

Researchers have traced protein that stops cells from becoming cancerous

Researchers find new risk factor for early-onset dementia

Researchers find new risk factor for early-onset dementia

New research finds sensory cortex develops late in fragile X syndrome defect

New research finds sensory cortex develops late in fragile X syndrome defect

Scientists uncover new gene that could help save sight of patients with inherited blindness

Scientists uncover new gene that could help save sight of patients with inherited blindness

4SC AG announces the first treatment in Phase I clinical study of 4SC-205

4SC AG announces the first treatment in Phase I clinical study of 4SC-205

Study shows cellular circuitry is more complex than previously thought

Study shows cellular circuitry is more complex than previously thought

Results validating performance of GSN’s proprietary Parental Support technology published

Results validating performance of GSN’s proprietary Parental Support technology published

Defective chromosome cause of severe obesity

Defective chromosome cause of severe obesity

New research shows tumor suppressor p53 prevents cancer progression in cells

New research shows tumor suppressor p53 prevents cancer progression in cells

GSA announces recipients of 2010 awards for distinguished service in the field of genetics

GSA announces recipients of 2010 awards for distinguished service in the field of genetics

CAMH signs licensing agreement to develop and market genetic test for degenerative muscle disorder

CAMH signs licensing agreement to develop and market genetic test for degenerative muscle disorder

Down Syndrome, menopause, dementia and death

Down Syndrome, menopause, dementia and death

Women experiencing early menopause could develop dementia at a younger age

Women experiencing early menopause could develop dementia at a younger age

Facial and brain anomalies in holoprosencephaly related chromosome aberrations characterized

Facial and brain anomalies in holoprosencephaly related chromosome aberrations characterized

MBL generates human monoclonal antibodies against pandemic A type influenza virus

MBL generates human monoclonal antibodies against pandemic A type influenza virus

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