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CRISPR off-switch discovered: Safer gene editing for future therapies

Using CRISPR, an immune system bacteria use to protect themselves from viruses, scientists have harnessed the power to edit genetic information within cells.

19 Jan 2024

Insilico Medicine leverages AI to identify promising new target for breast and gynecological cancers

Insilico Medicine("Insilico"), a clinical stage generative artificial intelligence (AI)-driven drug discovery company, recently published an early research that it has identified MYT1 as a promising new therapeutic target for breast and gynecological cancer, and discovered a series of novel, potent, and highly selective inhibitors specifically targeting MYT1.

19 Jan 2024

Study shows Omicron variants evade immune system like predecessors, suggesting key evolutionary trait in SARS-CoV-2

Researchers compared SARS-CoV-2 Omicron variant of concern replication in human cell lines and primary airway cultures and measured host responses to infection.

19 Jan 2024

Genotyping technology speeds up Covid variant identification

Genotyping technology detects Covid variants more quickly and cheaply than ever before – according to research from the University of East Anglia and the UK Health Security Agency.

17 Jan 2024

Anti-HIV drugs can be used to prevent inflammatory complications of bacterial sepsis

Bacterial infections can lead to the formation of abscesses - pockets of dead cells and debris surrounded by inflammatory immune cells. Bacteria multiply within abscesses, causing more inflammation and further damage to surrounding tissues.

17 Jan 2024

Comprehensive analysis of more than 2 million SARS-CoV-2 samples detects co-infections and intra-host recombination

Researchers evaluated the prevalence of co-infection and intra-host recombination in over 2 million global SARS-CoV-2 cases and developed strategies for accurate identification and analysis of recombinant strains.

17 Jan 2024

Review of traditional treatments and novel nutritional interventions for sickle cell disease

Nutrition-related studies involving sickle cell disease (SCD) patients, particularly those in Africa.

17 Jan 2024

New USC study reveals how DNA loops silence gene activity

The blueprint for human life lies within the DNA in the nucleus of each of our cells. In human cells, around six and a half feet of this genetic material must be condensed to fit inside the nucleus. DNA condensation is not random.

16 Jan 2024

Combining health data with whole genome sequence data in cancer patients can help doctors provide more tailored care

Researchers evaluated the impact of integrating whole-genome sequencing data with clinical outcomes across 13,880 tumors from 33 cancer types, assessing precision care potentials within the UK NHS through the 100,000 Genomes Cancer Programme.

16 Jan 2024

Pioneering Genomic Progress: An Interview with Rami Mehio, Illumina's Software and Informatics Expert

In this interview, Rami Mehio, head of software and informatics at Illumina, shares his experiences and contributions to major genomic projects like the UK Biobank's whole genome sequencing. He discusses the challenges and innovations in genomic data analysis, highlighting Illumina's role in advancing genetic research and precision medicine.

From Illumina, Inc. 15 Jan 2024

Ancient genomes reveal origins of multiple sclerosis risk in Europe

Researchers investigated the variables contributing to geographical heterogeneity in multiple sclerosis prevalence and the impact of genetic and environmental factors on the disease's development.

15 Jan 2024

International research collaboration leads to breakthrough in antibiotic resistance testing using DNA sequencing

The accuracy of antibiotic resistance determination from Enterococcus faecium genomes for diagnostic purposes.

15 Jan 2024

Study explores intratumoral microbiota as a novel frontier in cancer research

Researchers review the role of intratumoral microbiota in cancer development, suggesting its potential in predicting and treating various cancers.

14 Jan 2024

Ancient DNA traces multiple sclerosis origins to 5,000-year-old migrations

Researchers create the world's largest ancient human gene bank, linking genes to multiple sclerosis risk and tracing its origins to migrations 5,000 years ago.

13 Jan 2024

New analysis of cancer cells identifies 370 targets for smarter, personalized treatments

A new, systematic analysis of cancer cells identifies 370 candidate priority drug targets across 27 cancer types, including breast, lung and ovarian cancers.

13 Jan 2024

RBM5 identified as key regulator of HOXA9 in acute myeloid leukemia

The protein HOXA9 is overexpressed in most acute myeloid leukemia (AML) cases and is associated with poor patient outcomes.

12 Jan 2024

Drug-resistant Candida: Study uncovers evolutionary tricks of a fungal pathogen

Global fungal infections, which affect one billion people and cause 1.5 million deaths each year, are on the rise due to the increasing number of medical treatments that heighten vulnerability.

12 Jan 2024

Dark chocolate cuts hypertension risk: Sweet news from latest study

Study finds dark chocolate intake significantly lowers the risk of essential hypertension, suggesting a beneficial role in cardiovascular health.

12 Jan 2024

Genetics linked to BMI differences across socio-economic groups, study finds

Study in the International Journal of Obesity finds genetic factors contribute to socio-economic position (SEP) related differences in BMI, with lower SEP groups showing higher genetic predisposition to increased BMI.

11 Jan 2024

Groundbreaking study uncovers hundreds of genetic markers linked to insulin resistance

A genome-wide study of 402,398 individuals identifies 369 SNPs associated with insulin resistance, offering insights into metabolic diseases and potential therapeutic targets.

11 Jan 2024

Genome News and Research

CRISPR off-switch discovered: Safer gene editing for future therapies

Insilico Medicine leverages AI to identify promising new target for breast and gynecological cancers

Study shows Omicron variants evade immune system like predecessors, suggesting key evolutionary trait in SARS-CoV-2

Genotyping technology speeds up Covid variant identification

Anti-HIV drugs can be used to prevent inflammatory complications of bacterial sepsis

Comprehensive analysis of more than 2 million SARS-CoV-2 samples detects co-infections and intra-host recombination

Review of traditional treatments and novel nutritional interventions for sickle cell disease

New USC study reveals how DNA loops silence gene activity

Combining health data with whole genome sequence data in cancer patients can help doctors provide more tailored care

Pioneering Genomic Progress: An Interview with Rami Mehio, Illumina's Software and Informatics Expert

Ancient genomes reveal origins of multiple sclerosis risk in Europe

International research collaboration leads to breakthrough in antibiotic resistance testing using DNA sequencing

Study explores intratumoral microbiota as a novel frontier in cancer research

Ancient DNA traces multiple sclerosis origins to 5,000-year-old migrations

New analysis of cancer cells identifies 370 targets for smarter, personalized treatments

RBM5 identified as key regulator of HOXA9 in acute myeloid leukemia

Drug-resistant Candida: Study uncovers evolutionary tricks of a fungal pathogen

Dark chocolate cuts hypertension risk: Sweet news from latest study

Genetics linked to BMI differences across socio-economic groups, study finds

Groundbreaking study uncovers hundreds of genetic markers linked to insulin resistance

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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