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Edible egg-derived IgY antibodies against SARS-CoV-2 Omicron

A new study posted to the bioRxiv* preprint server reports on the development of anti-RBD immunoglobulin Y (IgY) antibodies from chicken eggs to block the binding of the viral RBD to human ACE2 receptors. This approach has several advantages since chicken egg-derived IgY can be edible and polyclonal can target multiple epitopes, enhancing neutralizing activity.

23 Feb 2022

First reported case of a cat infected with SARS-CoV-2 Delta AY.3 variant

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is hurting our loved ones — even those that walk on four legs. Researchers from the University of Pennsylvania documented the recovery of an 11-year old indoor housecat living in Delaware who first presented to the veterinary hospital after experiencing distressing gastrointestinal symptoms.

23 Feb 2022

Tiny lipid-based nanoparticles carry genetic instructions directly into the lungs

Researchers at the Tufts University School of Engineering are building a reputation for precision targeting in drug delivery.

23 Feb 2022

Novel AI tool can spot difficult-to-diagnose cardiac conditions

Physician-scientists in the Smidt Heart Institute at Cedars-Sinai have created an artificial intelligence (AI) tool that can effectively identify and distinguish between two life-threatening heart conditions that are often easy to miss: hypertrophic cardiomyopathy and cardiac amyloidosis.

23 Feb 2022

Cardiopulmonary limitations six months after surviving COVID-19

A recent prospective cohort study assessed the cardiopulmonary effects in patients six months after COVID-19 infection.

23 Feb 2022

SARS-Cov-2 reinfection in Syrian hamsters does not result in disease

Researchers have been investigating the reinfection of different SARS-CoV-2 variants in Syrian hamsters and found that this does not seem to result in disease or any significant pulmonary pathology.

23 Feb 2022

Exploring the potential of mosaic RBD nanoparticles to fight SARS-CoV-2

Researchers explore the potential of mosaic receptor-binding domain nanoparticles in protective immunity against SARS-CoV-2

22 Feb 2022

Breath tests can help detect traces of SARS-CoV-2 virus

Traces of the SARS-CoV-2 coronavirus that causes COVID-19 can be detected in microscopically small fluid droplets exhaled during a very short time span.

22 Feb 2022

Study provides a potent biparatopic antibody against all SARS-CoV-2 variants of concern

Researchers demonstrated the potent neutralization of SARS-CoV-2 VOCs, including Omicron by the biparatopic human heavy chain variable domain.

22 Feb 2022

Lung microbiome alterations and secondary-infections in lethal COVID-19

Researchers examined how an interplay of host and microbial factors weakened immunity leading to secondary infections in COVID-19-infected individuals.

22 Feb 2022

Mouse-adapted virus model to study persistent COVID induced lung disease

Researchers develop a mouse model to identify early biomarkers and test countermeasures needed to detect and prevent PASC.

21 Feb 2022

Climate change is sickening, literally!

A news study highlights the change in disease spread with climate change across the globe.

21 Feb 2022

Broad-spectrum antiviral activity of picolinic acid against SARS-CoV-2 and Influenza A virus

Researchers investigate the potential of picolinic acid (PA) as an anti-SARS-CoV-2 treatment option.

21 Feb 2022

Study shows how neighborhood-level social vulnerability impacts COVID-19 hospitalization outcomes

COVID-19 has sent nearly 900,000 Americans to the hospital in the past two years. A new study shows that the ZIP codes they came from had a lot to do with how sick they were when they got to the hospital, and how much care they needed once they were there.

21 Feb 2022

Generic version of Viagra could be the long-waited remedy for dogs with megaesophagus

Sildenafil, the generic version of the drug known as Viagra, could be the long-waited remedy for a group of dogs with a rare disorder called megaesophagus.

21 Feb 2022

Study suggests non-classical inhibition of TBK1/IKKε is protective against severe COVID-19 immunopathology in vivo

A study posted suggested the inhibition of TBK1 and its homolog KKε could decrease the severity of COVID-19.

21 Feb 2022

Biochemical changes in lung physiology not responsible for severe clinical outcomes in the older population

Researchers investigated whether age-dependent changes in lung physiology make the elderly disproportionately susceptible to SARS-CoV-2 infection.

21 Feb 2022

Early antiretroviral therapy is crucial to fight against HIV and latent tuberculosis

Two weeks makes a big difference in treating the animal version of HIV and latent tuberculosis, researchers from Texas Biomedical Research Institute, Southwest National Primate Research Center and colleagues report this month in the Journal of Clinical Investigation.

18 Feb 2022

Study reports a highly attenuated SARS-CoV-2 that could serve as a live-attenuated vaccine platform

The research showed a highly attenuated SARS-CoV-2 strain that might be used as a live-attenuated vaccine platform and a BSL-2 experimental system.

18 Feb 2022

Study shows mink can be infected by Omicron and efficiently transmit the virus to other mink

Researchers have been examining the pathology and spread of the Omicron variant in mink.

18 Feb 2022

Lungs News and Research

Edible egg-derived IgY antibodies against SARS-CoV-2 Omicron

First reported case of a cat infected with SARS-CoV-2 Delta AY.3 variant

Tiny lipid-based nanoparticles carry genetic instructions directly into the lungs

Novel AI tool can spot difficult-to-diagnose cardiac conditions

Cardiopulmonary limitations six months after surviving COVID-19

SARS-Cov-2 reinfection in Syrian hamsters does not result in disease

Exploring the potential of mosaic RBD nanoparticles to fight SARS-CoV-2

Breath tests can help detect traces of SARS-CoV-2 virus

Study provides a potent biparatopic antibody against all SARS-CoV-2 variants of concern

Lung microbiome alterations and secondary-infections in lethal COVID-19

Mouse-adapted virus model to study persistent COVID induced lung disease

Climate change is sickening, literally!

Broad-spectrum antiviral activity of picolinic acid against SARS-CoV-2 and Influenza A virus

Study shows how neighborhood-level social vulnerability impacts COVID-19 hospitalization outcomes

Generic version of Viagra could be the long-waited remedy for dogs with megaesophagus

Study suggests non-classical inhibition of TBK1/IKKε is protective against severe COVID-19 immunopathology in vivo

Biochemical changes in lung physiology not responsible for severe clinical outcomes in the older population

Early antiretroviral therapy is crucial to fight against HIV and latent tuberculosis

Study reports a highly attenuated SARS-CoV-2 that could serve as a live-attenuated vaccine platform

Study shows mink can be infected by Omicron and efficiently transmit the virus to other mink

The ultimate guide to lung research tools and protocols eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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