Membrane News and Research

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Hemp compounds show ability to prevent the entry of SARS-CoV-2 into cells

Hemp compounds identified by Oregon State University research via a chemical screening technique invented at OSU show the ability to prevent the virus that causes COVID-19 from entering human cells.

11 Jan 2022

Manipulating voltage patterns in tumor cells reduces breast cancer metastasis in animal models

In normal cells, electrical voltage patterns provide a blueprint for orderly growth. But with cancer, the opposite happens.

11 Jan 2022

First patient-derived stem cell model developed for studying oculocutaneous albinism

Researchers at the National Eye Institute have developed the first patient-derived stem cell model for studying eye conditions related to oculocutaneous albinism (OCA).

11 Jan 2022

Unraveling the early host-immune response to SARS-CoV-2 in mild COVID-19 infections

In a new study, researchers determined the early immune response to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) during mild coronavirus disease 2019 (COVID-19) in rhesus macaques.

11 Jan 2022

Study finds T cell response mostly conserved against SARS-CoV-2 Omicron variant following infection or vaccination

A new preprint examines the extent of protection offered by T cell responses to primary vaccination and/or natural infection with the virus.

11 Jan 2022

Multiscale model reveals the importance of lipids to the signaling dynamics of RAS proteins

Lawrence Livermore National Laboratory researchers and a multi-institutional team of scientists have developed a highly detailed, machine learning-backed multiscale model revealing the importance of lipids to the signaling dynamics of RAS, a family of proteins whose mutations are linked to numerous cancers.

10 Jan 2022

SARS-CoV-2 viral mutations shown to have a limited effect on T cell immunity

New research suggests that viral mutations have a minimal effect on T cell immunity, which could explain the protection provided by vaccination against severe COVID-19, despite the significant loss of neutralizing antibodies.

10 Jan 2022

T cells induced by common cold coronaviruses play a protective role against COVID-19 infection

A new study, published in Nature Communications and led by Imperial College London researchers, provides the first evidence of a protective role for these T cells.

10 Jan 2022

SARS-CoV-2 spike engagement of ACE2 shown to prime S2′ site cleavage and fusion initiation

In a new study, researchers used a cell-cell fusion assay to extract potentially cleaved spike protein products from syncytia in order to explore the functional and biochemical characteristics of spike (S) protein when it engages its receptor ACE2 in living cells.

10 Jan 2022

Researchers plan to review the effect of SARS-CoV-2 on male reproductive health

In a protocol published in BMJ Open, researchers from the Chengdu University of Traditional Chinese Medicine plan to review current studies in this area.

10 Jan 2022

Engineered small extracellular vesicles for the neutralization of SARS-CoV-2

Characterizing these engineered sEVs, the researchers demonstrated that the soluble angiotensin-converting enzyme 2 (sACE-2) loaded sEV successfully binds and thus inhibits the entry of wild-type SARS-CoV-2 as well as its variants, protecting against SARS-CoV-2 infection. They also demonstrated the therapeutic efficacy of these engineered sEVs in vivo.

9 Jan 2022

New appropriate use criteria for prostate-specific membrane antigen PET imaging published

The Society of Nuclear Medicine and Molecular Imaging and peer medical groups have issued appropriate use criteria (AUC) for prostate-specific membrane antigen (PSMA) PET imaging.

7 Jan 2022

From laboratory to clinic - Nanotechnology-enabled mRNA COVID-19 vaccines

In a recently published article in the journal Nano-Micro Letters, scientists have provided an in-depth review on the application and benefits of nanotechnology in the development of coronavirus disease 2019 (COVID-19) vaccines.

7 Jan 2022

Researchers study immune cell invasion process in living fruit fly embryos

To fight infections and heal injuries, immune cells need to enter tissue. They also need to invade tumors to fight them from within.

6 Jan 2022

Researchers identify how a critical schistosomiasis drug works on the molecular level

Independent teams from Texas Biomedical Research Institute and the Medical College of Wisconsin have published two papers in Science Translational Medicine identifying how the only approved drug to treat schistosomiasis, a widespread parasitic worm infection, works on the molecular level.

6 Jan 2022

Membrane News and Research

Hemp compounds show ability to prevent the entry of SARS-CoV-2 into cells

Manipulating voltage patterns in tumor cells reduces breast cancer metastasis in animal models

First patient-derived stem cell model developed for studying oculocutaneous albinism

Unraveling the early host-immune response to SARS-CoV-2 in mild COVID-19 infections

Study finds T cell response mostly conserved against SARS-CoV-2 Omicron variant following infection or vaccination

Multiscale model reveals the importance of lipids to the signaling dynamics of RAS proteins

SARS-CoV-2 viral mutations shown to have a limited effect on T cell immunity

T cells induced by common cold coronaviruses play a protective role against COVID-19 infection

SARS-CoV-2 spike engagement of ACE2 shown to prime S2′ site cleavage and fusion initiation

Researchers plan to review the effect of SARS-CoV-2 on male reproductive health

Engineered small extracellular vesicles for the neutralization of SARS-CoV-2

New appropriate use criteria for prostate-specific membrane antigen PET imaging published

From laboratory to clinic - Nanotechnology-enabled mRNA COVID-19 vaccines

Researchers study immune cell invasion process in living fruit fly embryos

Researchers identify how a critical schistosomiasis drug works on the molecular level

Study identifies current mechanism of action behind reduced severity of Omicron variant COVID-19 infection

Emergence of a new SARS-CoV-2 variant from Southern France

Host kinase identified as an inhibition target for SARS-CoV-2

Serological antibody response to SARS-CoV-2 infection at a population level

Study finds all three proteins required for SARS-CoV-2 infection present in human glossopharyngeal and vagal nerves

New Approach Methodologies, the 3Rs and Multimodal Imaging in Preclinical Research - eBook eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo