Pathogen News and Research

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New genetic editing tools could stop the spread of mosquito diseases

Since the onset of the CRISPR genetic editing revolution, scientists have been working to leverage the technology in the development of gene drives that target pathogen-spreading mosquitoes such as Anopheles and Aedes species, which spread malaria, dengue and other life-threatening diseases.

29 May 2021

Researcher investigates the behavior and life cycle of most infectious pathogenic bacteria

28 May 2021

Will emerging SARS-CoV-2 variants affect T cell immunity? A meta-analysis

New research by a team of scientists at The Hong Kong University of Science and Technology sheds light on the epitopic targets of SARS-CoV-2 by T cells in COVID-19 convalescents. The team’s findings suggest that the epitopes targeted by T cells during infection may not be affected by the emergence of SARS-CoV-2 variants.

28 May 2021

WHO and Swiss Confederation launch Biohub facility to improve sharing and analysis of viruses

The World Health Organization (WHO) and the Swiss Confederation today signed a Memorandum of Understanding to launch the first WHO BioHub Facility as part of the WHO BioHub System, which was announced in November 2020. This facility will enhance the rapid sharing of viruses and other pathogens between laboratories and partners globally.

28 May 2021

Researchers develop “cell encapsulation” technology to stimulate immunity to fight cancer

Immunotherapy techniques developed in oncology to combat cancerous cells have great potential for fighting viruses.

27 May 2021

Vagus nerve stimulation may be a potential adjunct therapy for COVID-19

COVID-19 was initially described as lung inflammation, or pneumonia, in older adults. However, we now know that SARS-CoV-2 infections can cause a wide range of symptoms in people of all ages, ranging from no symptoms at all to systemic inflammation and even death.

27 May 2021

Study sheds new light on complex dynamics involved in microbial infections

Included in the vast fallout stemming from the COVID-19 pandemic, scientists are paying closer attention to microbial infections and how life forms defend against attacks from pathogens.

27 May 2021

Can certain aircraft boarding procedures increase SARS-CoV-2 transmission risks?

In a study published in the Royal Society Open Science journal, researchers simulated many aircraft boarding processes to assess their impact on social proximity during boarding. They also studied the dominant mechanisms by which these processes generate social proximity. The researchers systematically measured proximity by measuring the number of contacts originating from the following situations: 1. contacts between seated passenger pairs; 2. contacts between aisle passenger pairs; and 3. contacts between a seated passenger and an aisle passenger.

26 May 2021

Salmonella bacteria colonize the gut using intestinal epithelial cells

The immune system's attempt to eliminate Salmonella bacteria from the gastrointestinal (GI) tract instead facilitates colonization of the intestinal tract and fecal shedding, according to National Institutes of Health scientists.

26 May 2021

New SARS-CoV-2 variants emerge among children in United States, suggests study

As the coronavirus disease 2019 (COVID-19) pandemic approaches its eighteenth month, new variants of concern (VOCs) of the causative pathogen – severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – continue to emerge all over the world. A new study explores the emergence of such VOCs among young children, below 12 years of age, and the potential consequences of this phenomenon.

26 May 2021

Tissue-resident memory T cells found in lungs of people who had COVID-19 10 months ago

In recent research by Judith Grau-Expósito et al., scientists identify circulating virus-specific T cell responses during acute SARS-CoV-2 infection with functional, migratory, and apoptotic patterns modulated by viral proteins and associated with clinical outcome.

26 May 2021

Previous H3N2 influenza A infection may explain some cases of severe COVID-19

According to research from the University of California, some cases of severe coronavirus disease 2019 (COVID-19) may be related to the immunological memory of previous H3N2 influenza A infection.

26 May 2021

Modeling the risk of SARS-CoV-2 outbreaks upon lifting non-pharmaceutical interventions (NPIs)

In a paper recently uploaded to the preprint server medRxiv* by Sachak-Patwa et al. (May 22nd, 2021), mathematical models are developed to assess the probability and impact of such localized outbreaks, accounting for changing general immunity levels in the population as vaccines are distributed.

25 May 2021

Researchers develop a novel probiotic formulation with high anti-SARS-CoV-2 potency

A team of international scientists recently conducted a randomized clinical trial to assess the safety and efficacy profiles of a novel probiotic formulation in symptomatic coronavirus disease 2019 (COVID-19) patients. The findings indicate that the probiotic formulation is highly effective in reducing symptom severity in COVID-19 patients without causing any adverse events.

25 May 2021

New testing protocol for SARS-CoV-2 can process thousands of samples within 48 hours

Researchers at the Vienna BioCenter designed a testing protocol for SARS-CoV-2 that can process tens of thousands of samples in less than 48 hours. The method, called SARSeq, is published in the journal Nature Communications and could be adapted to many more pathogens.

25 May 2021

Could 6′,6′-difluoro-aristeromycin (DFA) have broad-spectrum antiviral potential against coronaviruses?

Researchers at the Leiden University Medical Center demonstrated that low-micromolar concentrations of 6′,6′-difluoro24 aristeromycin (DFA), an adenosine nucleoside analog, strongly inhibits the replication of Middle East respiratory syndrome coronavirus (MERS-CoV) in a cell-based infection assay.

25 May 2021

Why COVID-19 patients have more pathogenic bacteria in their noses

Researchers compared the nasal microbiome of coronavirus disease 2019 (COVID-19) patients, healthy individuals, and healthcare workers. These studies indicated an increase in the pathogen Pseudomonas aeruginosa present in the nasal microbiome of COVID-19 patients, which may be responsible for other secondary infections.

24 May 2021

Pathogen News and Research

New genetic editing tools could stop the spread of mosquito diseases

Researcher investigates the behavior and life cycle of most infectious pathogenic bacteria

Will emerging SARS-CoV-2 variants affect T cell immunity? A meta-analysis

WHO and Swiss Confederation launch Biohub facility to improve sharing and analysis of viruses

Researchers develop “cell encapsulation” technology to stimulate immunity to fight cancer

Vagus nerve stimulation may be a potential adjunct therapy for COVID-19

Study sheds new light on complex dynamics involved in microbial infections

Can certain aircraft boarding procedures increase SARS-CoV-2 transmission risks?

Salmonella bacteria colonize the gut using intestinal epithelial cells

New SARS-CoV-2 variants emerge among children in United States, suggests study

Tissue-resident memory T cells found in lungs of people who had COVID-19 10 months ago

Previous H3N2 influenza A infection may explain some cases of severe COVID-19

Modeling the risk of SARS-CoV-2 outbreaks upon lifting non-pharmaceutical interventions (NPIs)

Researchers develop a novel probiotic formulation with high anti-SARS-CoV-2 potency

New testing protocol for SARS-CoV-2 can process thousands of samples within 48 hours

Could 6′,6′-difluoro-aristeromycin (DFA) have broad-spectrum antiviral potential against coronaviruses?

Why COVID-19 patients have more pathogenic bacteria in their noses

Researchers investigate link between the liver’s immune system composition and NASH pathology

Researchers identify factors influencing vaccine hesitancy in USA

Computationally designed peptide blocks the entry of SARS-CoV, SARS-CoV-2, and MERS-CoV

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