Respiratory News and Research

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Chimpanzee adenoviruses can be used as vaccine vectors: Research

In recent years, scientists have studied the possibility of using engineered human adenoviruses as vaccines against diseases such as HIV, tuberculosis, and malaria. In this approach, adenoviruses, which commonly cause respiratory-tract infections, are rendered relatively harmless before they are used as vectors to deliver genes from pathogens, which in turn stimulate the body to generate a protective immune response.

12 Aug 2010

Advanced Life Sciences second-quarter net loss decreases to $2.1 million

11 Aug 2010

SMI/Omega development team receives fund to develop prototype fast multispectral endoscope

Cascade Technologies, Inc., announced today that its wholly-owned subsidiary Spectral Molecular Imaging, Inc. (SMI) will receive NIH research funding through a collaboration with Omega Optical of Brattleboro, Vermont. This effort will accelerate development of a new class of medical endoscopes enhanced with proprietary multispectral imaging technology. The principal investigators on the project are Dr. Gary Carver, Director of Research at Omega Optical, and Dr. Daniel L. Farkas, Chairman and CEO of SMI.

11 Aug 2010

Advanced Life Sciences reaches SPA agreement with FDA for Restanza Phase 3 study

Advanced Life Sciences Holdings, Inc., a biopharmaceutical company engaged in the discovery, development and commercialization of novel drugs in the therapeutic areas of infection, oncology and respiratory diseases, announced today that it has reached agreement with the United States Food and Drug Administration (FDA), under the Special Protocol Assessment (SPA) process, on the design of its planned Phase 3 study of its novel once-daily oral antibiotic Restanza to treat community acquired bacterial pneumonia (CABP). The trial is the first prospectively designed superiority study to be conducted in CABP.

11 Aug 2010

Education, changes in reimbursement practices can reduce inappropriate antibiotic usage: Study

Improved drug coverage under Medicare Part D has led to an increase in the use of antibiotics by seniors, particularly of brand-name and more expensive drugs, according to a University of Pittsburgh Graduate School of Public Health study. Published in the Aug. 23 issue of Archives of Internal Medicine and the first to explore spending on antibiotics under Medicare Part D, the study suggests recent changes in drug coverage improved the use of antibiotics for pneumonia, but could lead to unnecessary spending on expensive broad-spectrum antibiotics and the overuse of inappropriate antibiotics.

11 Aug 2010

Study suggests zinc supplementation may reduce pneumonia risk

A high proportion of nursing facility residents were found to have low serum (blood) zinc concentrations during an observational study funded by the Agricultural Research Service (ARS) and the National Institute of Aging. The scientists found that those with normal blood zinc concentrations were about 50 percent less likely to develop pneumonia than those with low concentrations.

11 Aug 2010

China Pharma second-quarter revenue increases 22% to $16.6 million

China Pharma Holdings, Inc., a leading fully-integrated specialty pharmaceuticals company in China, today announced financial results for the second quarter ended June 30, 2010.

10 Aug 2010

Surveillance systems find no major disease outbreaks since Haiti quake; Media examine aid disbursements

Haitian and U.S. public health experts recently reported that two new surveillance systems set up in Haiti after the January earthquake showed that no major disease outbreaks had developed and that the new systems could be part of the foundation of the country's health system in the long term, Reuters reports. The findings were published Friday in the CDC's Morbidity and Mortality Weekly Report.

10 Aug 2010

Three-year efficacy data on STELARA for psoriasis presented at American Academy of Dermatology meeting

New study findings showed that a majority of patients with moderate to severe plaque psoriasis who had a previous response to STELARA® (ustekinumab) sustained a clinical response for up to three years with continued treatment regardless of their body weight. Investigators also presented findings from an integrated safety analysis that included data from one Phase 2 and three Phase 3 trials in which treatment with STELARA demonstrated a favorable benefit-risk profile for up to three years of treatment, consistent with previous analyses.

10 Aug 2010

Oil rig workers access healthcare via telemedicine

Without hands-on access to doctors and hospitals, oil rig workers who become sick or injured increasingly rely on telemedicine "visits" with physicians and specialists on land, a trend explored in detail in an article published in Telemedicine and e-Health, a peer-reviewed journal published by Mary Ann Liebert, Inc.

10 Aug 2010

Study on ethnic disparities in pediatric asthma in Latino and non-Latino children

A new study by researchers at the Bradley Hasbro Children's Research Center and the University of Puerto Rico may help explain some of the well-documented ethnic disparities in pediatric asthma.

10 Aug 2010

Study suggests reimbursements can address inappropriate antibiotic usage

Antibiotic use appears to have increased among older adults whose prescription drug coverage improved as a result of enrolling in Medicare Part D, with the largest increases for broad-spectrum, newer and more expensive drugs, according to a report in the August 9/23 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

10 Aug 2010

U.N. says nearly 14M Pakistanis affected by floods

On Monday the U.N. said that 13.8 million people have been affected by the floods in Pakistan as the death toll has now reached 1,600, Agence France-Presse reports.

9 Aug 2010

Morphine plus oxycodone IV combination exhibits improved analgesia, tolerability compared to IV morphine

QRxPharma Limited announced today positive results of its Phase 2 comparative proof-of-concept study to evaluate the efficacy and safety of its IV (intravenous) formulation of morphine plus oxycodone versus IV morphine alone for the treatment of moderate to severe post-operative pain in patients following hip replacement surgery. The main findings demonstrated that QRxPharma's formulation of MoxDuo IV resulted in fewer side effects and offered better pain relief than morphine alone.

9 Aug 2010

Myconostica announces CE marking for MycAssay Aspergillus and Pneumocystis on additional platforms

Myconostica Ltd, the UK-based medical diagnostic company developing and commercialising rapid and highly specific tests for life-threatening fungal infections, today announces the CE marking of its lead products MycAssay™ Aspergillus and MycAssay™ Pneumocystis on the Roche Lightcycler® 2.0 and Stratagene Mx3000 series platforms.

9 Aug 2010

Allergy shots can cause systemic side effects: Study

Allergy shots can reduce symptoms of asthma, use of inhaled medications and allergy-related asthma attacks, confirms an updated review of studies. Yet, the treatment can also cause systemic side effects that range from a stuffy nose to fatal anaphylactic shock.About 30 percent of asthma patients experience improved breathing after receiving a series of injections that desensitize their immune systems to specific irritants, according to the review. The medical term for this treatment protocol is allergen immunotherapy.

9 Aug 2010

Ingen reports 1,200% increase in sales for fiscal 2010

Ingen Technologies, Inc., an emerging medical device manufacturer developing innovative solutions for the respiratory market, with a new patented and proprietary medical product line targeting the $8 billion respiratory market, today announced that its Annual Report has been filed with the OTC Markets, while auditors have completed and filed required restatements needed to return to "fully reporting" status.

7 Aug 2010

Myths and realities of Medicare bidding program for durable medical equipment

Providers of home medical equipment and services across California are proposing a fiscally responsible alternative to the mislabeled "competitive" bidding scheme currently under way in Medicare that will actually discourage competition, reduce access to care for many of California's 4.6 million Medicare beneficiaries, and put thousands of California homecare providers out of business.

7 Aug 2010

Cornerstone announces ANDA filing for generic Tussionex

Cornerstone Therapeutics Inc., a specialty pharmaceutical company focused on acquiring, developing and commercializing significant products primarily for the respiratory and related markets, today announced that its product candidate CRTX-067 is an ANDA filing for a generic 10 mg chlorpheniramine polistirex/8 mg hydrocodone polistirex suspension product that will be a generic substitute for the product currently sold under the Tussionex brand name by UCB, Inc.

7 Aug 2010

ViroPharma announces data on safety, efficacy of Cinryze to treat acute angioedema attacks

ViroPharma Incorporated today announced that data from Phase 3 studies of Cinryze (C1 esterase inhibitor [human]) have been published in the August 5, 2010 issue of the New England Journal of Medicine. The paper entitled Nanofiltered C1 Inhibitor Concentrate for Treatment of Hereditary Angioedema by Dr. Bruce L. Zuraw et al. describes the safety and efficacy of Cinryze in treating and preventing attacks of hereditary angioedema. Cinryze is the first and only FDA-approved C1 esterase inhibitor therapy indicated for routine prophylaxis against angioedema attacks in adolescent and adult patients with hereditary angioedema (HAE), a rare, debilitating and potentially fatal disease; it is not approved by the FDA to treat acute angioedema attacks.

6 Aug 2010

Respiratory News and Research

Chimpanzee adenoviruses can be used as vaccine vectors: Research

Advanced Life Sciences second-quarter net loss decreases to $2.1 million

SMI/Omega development team receives fund to develop prototype fast multispectral endoscope

Advanced Life Sciences reaches SPA agreement with FDA for Restanza Phase 3 study

Education, changes in reimbursement practices can reduce inappropriate antibiotic usage: Study

Study suggests zinc supplementation may reduce pneumonia risk

China Pharma second-quarter revenue increases 22% to $16.6 million

Surveillance systems find no major disease outbreaks since Haiti quake; Media examine aid disbursements

Three-year efficacy data on STELARA for psoriasis presented at American Academy of Dermatology meeting

Oil rig workers access healthcare via telemedicine

Study on ethnic disparities in pediatric asthma in Latino and non-Latino children

Study suggests reimbursements can address inappropriate antibiotic usage

U.N. says nearly 14M Pakistanis affected by floods

Morphine plus oxycodone IV combination exhibits improved analgesia, tolerability compared to IV morphine

Myconostica announces CE marking for MycAssay Aspergillus and Pneumocystis on additional platforms

Allergy shots can cause systemic side effects: Study

Ingen reports 1,200% increase in sales for fiscal 2010

Myths and realities of Medicare bidding program for durable medical equipment

Cornerstone announces ANDA filing for generic Tussionex

ViroPharma announces data on safety, efficacy of Cinryze to treat acute angioedema attacks

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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