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Quest for effective HIV vaccines present new possibilities, challenges

A vaccine that prevents HIV infection remains an important goal in the fight against AIDS, but the current top HIV vaccine candidates may not work in this way, say scientists at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH).

17 May 2007

Health effects of isoflavones and breast cancer

Are soy products healthy additions to a person's diet, safe alternatives to hormone-replacement therapy or cancer-causing agents" The answer, according to University of Illinois food science and human nutrition professor William Helferich, is, "It depends."

17 May 2007

Important new gene-silencing mechanism

Genes provide the instructions used by the individual cells to produce the many different proteins that make up the body.

17 May 2007

Clearer view of synaptic plasticity

Scientists are keenly studying how neurons form synapses--the physical and chemical connections between neurons--and the "pruning" of neural circuits during development, not least because synaptic abnormalities may partially underlie many developmental and neurodegenerative diseases.

17 May 2007

New findings on microRNAs

Over 30% of our genes are under the control of small molecules called microRNAs.

17 May 2007

Herpes infection may be symbiotic

Mice with chronic herpes virus infections can better resist the bacterium that causes plague and a bacterium that causes one kind of food poisoning, researchers report in Nature.

17 May 2007

Bovine protein called lactoferrin aids in treatment of gastrointestinal disorder

Recent evidence suggests that therapy currently used to treat Helicobacter pylori (H. pylori) infection, a major cause of upper gastrointestinal disorders, is unsuccessful in around 25 percent of cases.

17 May 2007

Researchers catch moving proteins in mid-fold

Any photographer can vouch for the difficulty of capturing a clear picture of a moving target.

17 May 2007

ACE inhibitors help preserve kidney function in IgA nephropathy

For young patients with the kidney disease IgA nephropathy (IgAN), early treatment with angiotensin-converting enzyme (ACE) inhibitors can reduce the long-term risk of irreversible kidney damage, suggests a study in the June Journal of the American Society of Nephrology.

17 May 2007

Yin Yang 1 regulates early B cell development

A new paper in the May 15th issue of Genes & Development reveals how a protein called Yin Yang 1 regulates early B cell development.

17 May 2007

Model of proline dehydrogenase created

Researchers at the University of Missouri-Columbia recently created a model of proline dehydrogenase, an important cancer-preventing enzyme in the human body, and analyzed how it works.

17 May 2007

Innovation in child-allergy detection

In the past decade, food allergies have become a major point of concern for paediatricians, especially those treating very young children.

16 May 2007

Complement receptor 3 sends a signal to dampen the immune system

Researchers from The Children's Hospital of Philadelphia and The University of Pennsylvania reported that complement receptor 3 (CR3), a protein found on cell surfaces, inhibits dendritic cells, the sentinels of the immune system, from setting off an alarm signal that brings on a full immune response.

16 May 2007

Radically different approach to nuclear magnetic resonance

Detecting the molecular structure of a tiny protein using nuclear magnetic resonance (NMR) currently requires two things: a million-dollar machine the size of a massive SUV, and a large sample of the protein under study.

16 May 2007

Potential therapeutic target for autoimmune vasculitis

A potential therapeutic target for autoimmune vasculitis has been identified by researchers of the Franz Volhard Clinic for Cardiovascular Diseases (FVK) of the Charity – University Medicine Berlin/HELIOS-Klinikum and the Max Delbruck Center for Molecular Medicine (MDC) Berlin-Buch.

16 May 2007