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Early life exposure to traffic-related air pollution may cause structural brain changes at age 12

A new study suggests that significant early childhood exposure to traffic-related air pollution (TRAP) is associated with structural changes in the brain at the age of 12.

24 Jan 2020

Determining Microsatellite Instability Status Using Multiplex PCR-Based Methods

Determining microsatellite instability status using multiplex PCR-based methods used to screen for Lynch Syndrome, a dominant hereditary cancer propensity.

From Promega Corporation 24 Jan 2020

First glioblastoma patient treated with genetically modified poliovirus at UH

University Hospitals Seidman Cancer Center treated its first patient in a new clinical trial to validate the groundbreaking effects of the poliovirus on glioblastoma, a deadly Grade IV cancer of the brain.

24 Jan 2020

30-year study of MSUD highlights critical need for more effective disease-modifying therapies

A new study analyzes 30 years of patient data and details the clinical course of 184 individuals with genetically diverse forms of Maple Syrup Urine Disease (MSUD), which is among the most volatile and dangerous inherited metabolic disorders.

24 Jan 2020

CRNAs offer safe, affordable solution for care as rural hospitals continue to close

As the 2020 presidential candidates propose to fix U.S. healthcare, rural hospitals across the country continue to close. Since the 2018 midterms, about 66 percent of primary care physician shortages have been in rural and partially rural areas.

24 Jan 2020

Something far deadlier than the Wuhan virus lurks near you

There's a deadly virus spreading from state to state. It preys on the most vulnerable, striking the sick and the old without mercy. In just the past few months, it has claimed the lives of at least 39 children.

24 Jan 2020

New stigma-reduction intervention benefits obese individuals who struggle with poor self-image

People with obesity are often treated with less respect than other people, discriminated against, and socially devalued because of their weight.

24 Jan 2020

Three big AI projects in medicine to watch in 2020

Artificial intelligence (AI) is beginning to touch medicine in many different ways, from making diagnoses to triaging patients. Many AI enterprises will make headlines in 2020:

24 Jan 2020

Study provides insight into short-term outcome of status epilepticus patients

A new study published in Seizure gives insight into the short-term outcome of patients treated for status epilepticus in Kuopio University Hospital in Finland.

24 Jan 2020

New drug combination destroys bacterial infection that can be fatal to cystic fibrosis patients

A new treatment developed by researchers at Aston University and Birmingham Children's Hospital has been found to completely kill a bacterial infection that can be deadly to cystic fibrosis patients.

24 Jan 2020

Despite new doubts, ‘hotspotting’ help for heavy health care users marches on

A highly publicized approach to lowering health costs failed to pass rigorous study this month, but hospitals, insurers and government health programs don't intend to give up on the idea.

24 Jan 2020

Infectious disease expert explains about Wuhan coronavirus

A new coronavirus virus, likely first transmitted to people from animals at a market in the Chinese city of Wuhan, is making international headlines as disease detectives work to uncover what it is, how it's transmitted, and how deadly the virus actually is.

24 Jan 2020

Study: Benefits of fetal surgery to repair spina bifida continue through school age

The benefits of fetal surgery to repair spina bifida, a procedure pioneered at Vanderbilt University Medical Center (VUMC) in 1997, continue through school age, a National Institutes of Health (NIH) study reports today in the journal Pediatrics.

24 Jan 2020

RB1 alterations in cancer cells may lead to treatment resistance

The Cancer Genetics Group of the Josep Carreras Leukaemia Research Institute, led by Montse Sánchez-Céspedes, together with Luis Montuenga from CIMA, and Enriqueta Felip from Vall d'Hebron Hospital, has revealed that inactivation of RB1 through intragenic rearrangements is frequent in lung cancer cells from non-smoking patients with EGFR mutations.

24 Jan 2020

Study reveals new "crosstalk" between intestinal microbes and developing thymic cells

Newborns face unique immunological challenges immediately after birth. As they depart a relatively sterile fetal environment, they are abruptly exposed to a multitude of foreign antigens, the major burden of which is in the form of the microbiota newly colonizing the gastrointestinal tract.

24 Jan 2020

Healing and hope for families affected by fragile X in Eastern Europe

Mothers and fathers and their young children crowded into an old, government-run children's hospital in Belgrade, Serbia, colorful, cartoonish drawings covering its hallway walls. Parents struggled to soothe their anxious, wriggly boys and girls. But they were patient, polite. It was, after all, a day unlike any other. A day for hope.

23 Jan 2020

Implementation of combined pediatric observation unit improves patient outcomes, satisfaction

It's a quandary facing many busy emergency departments across the country: how to treat young patients who require emergency care and a brief stay while reserving limited inpatient beds for the most acute cases.

23 Jan 2020

Fetal surgery for spina bifida makes a huge difference 10 years later

A new study published in the journal Pediatrics shows that children with spina bifida, a congenital spinal disorder, who had corrective surgery in the womb, show significantly more benefit than those whose operations were performed after birth, even a decade later. These children have more of a chance to walk by themselves and a lower risk of needing more surgeries, compared to those whose condition is corrected only after birth.

23 Jan 2020

New method could help doctors avoid ineffective or unnecessarily risky treatments

In a usual management setting, after a person has had a heart attack or stroke, algorithmic risk models are used to calculate the risk of death for the patient. These algorithms or models utilize various factors such as age of the patient, gender, previous history, family history, ethnicity etc.

23 Jan 2020

KHN’s ‘What the Health?’: SCOTUS punts on ACA case — for now

The Supreme Court has declined to take up immediately a case out of Texas that could overturn the entire Affordable Care Act. But that is not likely to stop the case from becoming a major political issue in the 2020 presidential and congressional campaigns.

23 Jan 2020

Hospital News and Research

Early life exposure to traffic-related air pollution may cause structural brain changes at age 12

Determining Microsatellite Instability Status Using Multiplex PCR-Based Methods

First glioblastoma patient treated with genetically modified poliovirus at UH

30-year study of MSUD highlights critical need for more effective disease-modifying therapies

CRNAs offer safe, affordable solution for care as rural hospitals continue to close

Something far deadlier than the Wuhan virus lurks near you

New stigma-reduction intervention benefits obese individuals who struggle with poor self-image

Three big AI projects in medicine to watch in 2020

Study provides insight into short-term outcome of status epilepticus patients

New drug combination destroys bacterial infection that can be fatal to cystic fibrosis patients

Despite new doubts, ‘hotspotting’ help for heavy health care users marches on

Infectious disease expert explains about Wuhan coronavirus

Study: Benefits of fetal surgery to repair spina bifida continue through school age

RB1 alterations in cancer cells may lead to treatment resistance

Study reveals new "crosstalk" between intestinal microbes and developing thymic cells

Healing and hope for families affected by fragile X in Eastern Europe

Implementation of combined pediatric observation unit improves patient outcomes, satisfaction

Fetal surgery for spina bifida makes a huge difference 10 years later

New method could help doctors avoid ineffective or unnecessarily risky treatments

KHN’s ‘What the Health?’: SCOTUS punts on ACA case — for now

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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