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Proteomic analysis of 2002 tumors reveals 11 distinct pan-cancer molecular subtypes

A new study that analyzed protein levels in 2,002 primary tumors from 14 tissue-based cancer types identified 11 distinct molecular subtypes, providing systematic knowledge that greatly expands a searchable online database that has become a go-to platform for cancer data analysis by users worldwide.

10 Jun 2022

Inhaled vaccines provide better protection and stronger immunity than nasal sprays, study confirms

McMaster University scientists who compared respiratory vaccine-delivery systems have confirmed that inhaled aerosol vaccines provide far better protection and stronger immunity than nasal sprays.

10 Jun 2022

Older adults with Type 1 diabetes have greater risk for muscle weakening, cardiovascular complications

Older adults with Type 1 diabetes (T1D) are at significantly higher risk of both muscle weakening and cardiovascular complications, say McMaster University researchers.

10 Jun 2022

Using artificial intelligence to discover new antivirals against COVID-19 and future pandemics

Research into drugs to treat mosquito-borne flaviviruses such as Zika and dengue as well as COVID-19will benefit from a major funding boost, says a group of international scientists using artificial intelligence to discover new oral antivirals.

10 Jun 2022

Stress protein in fibroblasts appears to be an attractive cancer drug target

A stress protein that is overactive in many types of tumor cells also has a key role in tumor-supporting cells called fibroblasts, and may be a good target for future cancer treatments, suggests a study from researchers at the Perelman School of Medicine at the University of Pennsylvania.

10 Jun 2022

Naturally-produced antibodies in mothers may enhance infants' immunity against bacterial pathogens

Researchers have known for some time that maternal breast milk provides critical nutrients for newborns, and antibodies from mothers vaccinated against a specific disease-causing bacterium or virus can be transferred via breast milk to babies.

10 Jun 2022

Deciphering the structure of nuclear pore complex piece by piece

Whatever you are doing, whether it is driving a car, going for a jog, or even at your laziest, eating chips and watching TV on the couch, there is an entire suite of molecular machinery inside each of your cells hard at work.

10 Jun 2022

Using a harmless amoeba to protect children from dangerous infections

Innovative efforts at the University of Virginia School of Medicine to use a harmless amoeba to protect children from dangerous infections has won critical financial support from The Hartwell Foundation.

10 Jun 2022

Creating CAR T cells without an immune brake

T cells are usually very good at eliminating diseased cells. But they seem to fail when it comes to tumor cells.

10 Jun 2022

Transgender college students more likely to suffer from sleep disorders and mental health issues

Transgender individuals are more likely to experience discrimination, isolation, and lack of social support.

10 Jun 2022

Long wait for justice: People in jail face delays for mental health care before they can stand trial

Beau Hampton’s long wait for psychiatric treatment began last year, after he was accused of attacking his foster father and charged with a misdemeanor.

10 Jun 2022

Medicaid weighs attaching strings to nursing home payments to improve patient care

The Biden administration is considering a requirement that the nation's 15,500 nursing homes spend most of their payments from Medicaid on direct care for residents and limit the amount that is used for operations, maintenance, and capital improvements or diverted to profits.

10 Jun 2022

Tackling psychological distress among older people in rural Australian communities

Psychological distress is acute for older people with multiple health difficulties in rural and remote areas of Australia, leading to higher health services use – but Flinders University researchers suggest that increased psychological screening in a clinical setting can help improve this situation.

10 Jun 2022

Research reveals why many cancers are vulnerable to FDA-approved IDH1 inhibitors

A drug used to target IDH1 mutations in select cancers also appears to inhibit the wild-type form of the enzyme, under certain conditions.

9 Jun 2022

New hot-melt tissue adhesive can heal operative wounds

NIMS has developed a hot-melt tissue adhesive (i.e., medical glue that is applied in a molten state) capable of healing operative wounds.

9 Jun 2022

First-in-class, anti-cancer mitochondrial drug found to be effective against most carcinoma cell lines

A study of the lead agent (CPI-613) in a class of anticancer drugs undergoing Food and Drug Administration (FDA) approved clinical trials reveals that CPI-613 is effective against most carcinoma cell lines, and, used in combination, could have efficacy against reducing some tumors.

9 Jun 2022

Inhaled recombinant IL-15 tested in pet dogs with metastatic lung disease from osteosarcoma or melanoma

A protein that the body naturally produces could become an important new immunotherapy drug in the cache of cancer-fighting tools available to oncologists.

9 Jun 2022

Alternative remedy to conventional root canals would regenerate lost tooth pulp

Each year, dentists in the United States perform more than 15 million root canals on infected teeth, removing the inflamed pulp and filling the emptied canal with inert materials such as rubber and cement. What remains is a mineral shell in place of a living tooth.

9 Jun 2022

Genomic analysis provides a deeper understanding of DCIS biology

A new study led by the global Cancer Grand Challenges PRECISION team, including researchers from The University of Texas MD Anderson Cancer Center, shifts the long-held belief that all invasive breast cancers following ductal carcinoma in situ (DCIS) arise from the original DCIS lesion.

9 Jun 2022

Study links SARS-CoV-2 specific T cells with inflammation and reduced lung function in long COVID

A new study published in today’s issue of PLoS Pathogens is the first to link SARS-CoV-2 specific T cells to lung function and those who suffer from long-term COVID symptoms (PASC). Long-covid currently affects hundreds of millions of Americans.

9 Jun 2022

Medicine News and Research

Proteomic analysis of 2002 tumors reveals 11 distinct pan-cancer molecular subtypes

Inhaled vaccines provide better protection and stronger immunity than nasal sprays, study confirms

Older adults with Type 1 diabetes have greater risk for muscle weakening, cardiovascular complications

Using artificial intelligence to discover new antivirals against COVID-19 and future pandemics

Stress protein in fibroblasts appears to be an attractive cancer drug target

Naturally-produced antibodies in mothers may enhance infants' immunity against bacterial pathogens

Deciphering the structure of nuclear pore complex piece by piece

Using a harmless amoeba to protect children from dangerous infections

Creating CAR T cells without an immune brake

Transgender college students more likely to suffer from sleep disorders and mental health issues

Long wait for justice: People in jail face delays for mental health care before they can stand trial

Medicaid weighs attaching strings to nursing home payments to improve patient care

Tackling psychological distress among older people in rural Australian communities

Research reveals why many cancers are vulnerable to FDA-approved IDH1 inhibitors

New hot-melt tissue adhesive can heal operative wounds

First-in-class, anti-cancer mitochondrial drug found to be effective against most carcinoma cell lines

Inhaled recombinant IL-15 tested in pet dogs with metastatic lung disease from osteosarcoma or melanoma

Alternative remedy to conventional root canals would regenerate lost tooth pulp

Genomic analysis provides a deeper understanding of DCIS biology

Study links SARS-CoV-2 specific T cells with inflammation and reduced lung function in long COVID

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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