Appetite News and Research

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FDA approves LONSURF for treatment of patients with metastatic colorectal cancer

Taiho Oncology, Inc. (U.S.), a subsidiary of Taiho Pharmaceutical Co., Ltd. (Japan), today announced that the U.S. Food and Drug Administration approved LONSURF (trifluridine and tipiracil), formerly known as TAS-102, for the treatment of patients with metastatic colorectal cancer (mCRC) who have been previously treated with fluoropyrimidine-, oxaliplatin- and irinotecan-based chemotherapy, an anti-VEGF biological therapy, and if RAS wild-type, an anti-EGFR therapy.

22 Sep 2015

Philadelphia College of Osteopathic Medicine professor discusses causes, consequences of weight stigma

There's a dark side to obesity that's only recently getting attention; millions of people from all walks of life are often stigmatized and even shamed based on their weight -and it's one of the most pervasive and acceptable forms of bias and discrimination. In advance of Weight Stigma Awareness Week (September 21-25), Stacey Cahn, PhD, associate professor of clinical psychology at Philadelphia College of Osteopathic Medicine, discusses the causes and consequences of weight stigma.

15 Sep 2015

Research shows people consume more food and drink when offered larger-sized portions, packages or tableware

A new review has produced the most conclusive evidence to date that people consume more food or non-alcoholic drinks when offered larger sized portions or when they use larger items of tableware.

15 Sep 2015

Helsinn, BIAL sign exclusive distribution and licence agreement for Anamorelin

Helsinn, the Swiss Group focused on building quality cancer care, and BIAL - Portela & Ca. S.A., one of the largest Iberian pharmaceutical companies, today announce that they have entered into an agreement for the exclusive distribution and licence rights to Anamorelin in Spain, Portugal, Angola and Mozambique.

8 Sep 2015

Studies suggests that insular cortex may hold key to treating addiction

A pair of studies suggests that a region of the brain - called the insular cortex - may hold the key to treating addiction. Scientists have come to this conclusion after finding that smokers who suffered a stroke in the insular cortex were far more likely to quit smoking and experience fewer and less severe withdrawal symptoms than those with strokes in other parts of the brain.

8 Sep 2015

New computational method reveals links between bacterial growth rates and type II diabetes, IBD

It is increasingly clear that the thousands of different bacteria living in our intestinal tract - our microbiome - have a major impact on our health. But the details of the microbiome's effects are still fairly murky.

3 Sep 2015

Household food insecurity increases likelihood of metabolic diseases in children

New research indicates that household food insecurity dramatically increases the likelihood of metabolic diseases in children, with many showing chronic disease markers before they graduate from high school.

3 Sep 2015

Preventing the build up of dangerous biofilms, ESCMID publishes guidelines

The European Society of Clinical Microbiology and Infectious Disease (ESCMID) – an organization that explores the risks and best practices in infectious disease – advocates the need for greater education, guidance and research on the build-up, treatment and prevention of biofilms, which contribute to antimicrobial resistance.

2 Sep 2015

Children's Hospital Los Angeles successfully implants Melody Transcatheter Pulmonary Valve in child actor

Cardiologists from Children's Hospital Los Angeles successfully implanted a Melody Transcatheter Pulmonary Valve in child actor Max Page, the boy who made headlines playing mini Darth Vader in a 2011 Super Bowl ad for Volkswagen.

28 Aug 2015

Smiling Brazil initiative sets example to other nations to eliminate healthcare disparities

Today, the International and American Associations for Dental Research (IADR/AADR) published a Discovery! article titled "10 Years of a National Oral Health Policy in Brazil: Innovation, Boldness and Numerous Challenges."

28 Aug 2015

School students eat less fruits and vegetables despite national push for healthier school lunches

Less than a month before Congress votes on whether to reauthorize a controversial program mandating healthier school lunches, a new study confirms the suspicions of school officials - many students are putting the fruits and vegetables they're now required to take straight into the trash, consuming fewer than they did before the law took effect.

26 Aug 2015

High dietary iron intake suppresses hormone that regulates appetite

Here's one more reason to cut down on the amount of red meat you eat. Using an animal model, researchers at Wake Forest Baptist Medical Center have found that dietary iron intake, equivalent to heavy red meat consumption, suppresses leptin, a hormone that regulates appetite.

25 Aug 2015

Variation in genetic mechanism increases fat storage and drives obesity

A specific gene region has long been suspected of contributing to obesity in humans but the precise mechanisms behind this were previously unclear. Now, researchers at the Technical University of Munich (TUM), Massachusetts Institute of Technology (MIT), Harvard Medical School and other partners have been able to show that a single genetic alteration in this region reduces thermogenesis (fat burning), instead increasing lipid storage.

24 Aug 2015

Teenage smokers experience guilt and shame

There are fewer smokers in the current generation of adolescents. Current figures show about 25 per cent of teens smoke, down dramatically from 40 per cent in 1987.

20 Aug 2015

Researchers uncover genetic circuit involved in obesity

Like many other conditions, obesity is caused by an interplay between genetic and environmental factors. While efforts to combat the obesity epidemic will need to include changes in diet and exercise, insights into the genes involved may also help with prevention and treatment.

20 Aug 2015

JRC foresight report on global food security

Long considered in relation to malnutrition and humanitarian aid, food security policy should be moving towards a much broader landscape and focusing on regular access to food for a population nearing nine billion towards 2030-2050, while addressing food insecurity for a fraction of communities, according to a JRC foresight report.

19 Aug 2015

Calorie control is key to losing or maintaining weight

Physical activity has many health benefits, ranging from reducing the risk of heart disease, diabetes and cancer to improving mental health and mood.

18 Aug 2015

Improved method for building proteins into antibodies

Some proteins exist so fleetingly in the bloodstream that they can't be given effectively as therapies. However, building them into larger proteins, such as antibodies, can make them persist long enough to be useful. Now a team led by scientists at The Scripps Research Institute (TSRI) has devised an improved method for accomplishing this protein-engineering feat.

14 Aug 2015

TSRI-led team devises selection-based, protein-engineering method to work on obesity therapy

Some proteins exist so fleetingly in the bloodstream that they can’t be given effectively as therapies. However, building them into larger proteins, such as antibodies, can make them persist long enough to be useful. Now a team led by scientists at The Scripps Research Institute has devised an improved method for accomplishing this protein-engineering feat.