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St. Jude researchers discover NLRP12 as a direct bridge from hemolysis to inflammatory disease

Infections and other diseases can cause red blood cells to rupture, releasing the oxygen-binding molecule hemoglobin, which breaks down into heme.

1 Jun 2023

Peptidomimetic antibiotics may be effective against resistant bacteria

Health professionals are in urgent need of new antibiotics to tackle resistant bacteria. Researchers at the University of Zurich and the company Spexis have now modified the chemical structure of naturally occurring peptides to develop antimicrobial molecules that bind to novel targets in the bacteria's metabolism.

1 Jun 2023

Real-world management and outcomes of U.S. patients treated with BpaL for rifampin-resistant tuberculosis

Researchers reported on the treatment of rifampin-resistant tuberculosis in the United States using the FDA approved bedaquiline, pretomanid, and linezolid (BPaL) therapy.

1 Jun 2023

Unique combination of intestinal bacteria in Japanese centenarians may be the key to long life

We are pursuing the dream of eternal life. We fast to stay healthy. And each year, we spend billions of kroner on treatment to make sure we stay alive. But some people turn 100 years old all by themselves. Why is that?

31 May 2023

New hope for low-cost biological cleanup of industrial pollutants

University of California, Riverside, chemical and environmental engineering scientists have identified two species of bacteria found in soil that break down a class of stubborn "forever chemicals," giving hope for low-cost biological cleanup of industrial pollutants.

30 May 2023

Verifying the healthcare, nutritional and environmental applications of new Antarctic bacteria

A scientific collaboration between the University of São Paulo (USP) in Ribeirão Preto, Brazil, and Clemente Estable Institute of Biological Research (IIBCE) in Montevideo, Uruguay, is experimenting with two new bacteria discovered in the Antarctic ten years ago, in order to verify the possibility of applications in healthcare, food processing and environmental rehabilitation.

30 May 2023

NmCV-5 vaccine safety and immunogenicity against bacterial meningitis in Mali and Gambia

Researchers evaluated the safety and non-inferiority of the pentavalent meningococcal NmCV-5 vaccine.

30 May 2023

Study highlights two strategies used by Salmonella to escape the human body's defenses

Like thieves that constantly look for ways to evade capture, Salmonella enterica, a disease-causing bacterium, uses various tactics to escape the human body's defence mechanisms.

26 May 2023

Makeup of microbiome in a person's tumor varies depending on early or late-onset colorectal cancer

Researchers at Georgetown University's Lombardi Comprehensive Cancer Center studied the microbiome of people with colorectal cancer and found the make-up of the bacteria, fungi and viruses in a person's tumor varied significantly depending on whether they were diagnosed with early-onset disease (age 45 or younger) or late-onset disease (age 65 or older).

26 May 2023

Scientists use AI to identify new antibiotic that could fight drug-resistant infections

Using an artificial intelligence algorithm, researchers at MIT and McMaster University have identified a new antibiotic that can kill a type of bacteria that is responsible for many drug-resistant infections.

25 May 2023

Identifying what makes some gut bacteria strains life-threatening in pre-term babies

Researchers from the Quadram Institute and University of East Anglia have identified what makes some strains of gut bacteria life-threatening in pre-term babies.

25 May 2023

New tool shows early promise to help reduce the spread of antimicrobial resistance

A new tool which could help reduce the spread of antimicrobial resistance is showing early promise, through exploiting a bacterial immune system as a gene editing tool.

25 May 2023

Statistical modeling based of Australian native possum excreta identifies locations of Buruli ulcer occurrence in humans

The study aimed to predict the future human Buruli ulcer case locations via statistical modelling.

25 May 2023

Gut bacteria toxins: A hidden trigger for Parkinson's disease?

Gut dysfunction and the presence of lipopolysaccharide (LPS) endotoxins contribute to the pathogenesis of Parkinson's disease (PD), leading to neuroinflammation and neurodegeneration. Modulating the gut microbiome and reducing LPS levels may hold potential as treatment strategies for PD.

24 May 2023

The antimicrobial potential of nanoparticles

Nanoparticles have widely been used as advanced tools for the diagnosis, prevention, and treatment of infectious diseases.

23 May 2023

New trial data validates a rapid diagnostic test for sepsis

Critical care physician Hollis O'Neal, MD, MSc, Associate Professor of Medicine at LSU Health New Orleans School of Medicine's Baton Rouge campus, presented data that validate a rapid diagnostic test for sepsis at the American Thoracic Society 2023 International Conference.

23 May 2023

Magnetic stimulation treats depression by reversing the direction of abnormal brain signals

Powerful magnetic pulses applied to the scalp to stimulate the brain can bring fast relief to many severely depressed patients for whom standard treatments have failed.

23 May 2023

Study findings offer hope for the development of novel treatments for leishmaniasis

In an article published in the journal Nature Communications, researchers at the University of São Paulo (USP) in Brazil show how protozoans of the genus Leishmania that cause leishmaniasis manipulate a protein that plays an essential role in the organism's defense in order to continue to replicate, preventing the body from vanquishing the disease.

23 May 2023

AI can help triage patients with respiratory symptoms before primary care clinic visit

Researchers from Iceland trained a machine learning model with artificial intelligence to triage patients with respiratory symptoms before the patients visit a primary care clinic.

23 May 2023

39th Barcelona BioMed Conference focuses on latest advances in proximity induction-based pharmacology

Targeted protein degradation uses different types of "degrading" drugs (degraders) to force proximity between a target protein (for example, a mutated protein that contributes to the development of a disease) and the cellular machinery that directs protein degradation.

23 May 2023

Bacterial News and Research

St. Jude researchers discover NLRP12 as a direct bridge from hemolysis to inflammatory disease

Peptidomimetic antibiotics may be effective against resistant bacteria

Real-world management and outcomes of U.S. patients treated with BpaL for rifampin-resistant tuberculosis

Unique combination of intestinal bacteria in Japanese centenarians may be the key to long life

New hope for low-cost biological cleanup of industrial pollutants

Verifying the healthcare, nutritional and environmental applications of new Antarctic bacteria

NmCV-5 vaccine safety and immunogenicity against bacterial meningitis in Mali and Gambia

Study highlights two strategies used by Salmonella to escape the human body's defenses

Makeup of microbiome in a person's tumor varies depending on early or late-onset colorectal cancer

Scientists use AI to identify new antibiotic that could fight drug-resistant infections

Identifying what makes some gut bacteria strains life-threatening in pre-term babies

New tool shows early promise to help reduce the spread of antimicrobial resistance

Statistical modeling based of Australian native possum excreta identifies locations of Buruli ulcer occurrence in humans

Gut bacteria toxins: A hidden trigger for Parkinson's disease?

The antimicrobial potential of nanoparticles

New trial data validates a rapid diagnostic test for sepsis

Magnetic stimulation treats depression by reversing the direction of abnormal brain signals

Study findings offer hope for the development of novel treatments for leishmaniasis

AI can help triage patients with respiratory symptoms before primary care clinic visit

39th Barcelona BioMed Conference focuses on latest advances in proximity induction-based pharmacology

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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