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Nanopore technology allows point-of-care SARS-CoV-2 genomic sequencing

As the SARS-CoV-2 continues to spread worldwide and cause disease and death on a devastating scale, genomic sequencing has become a primary method of keeping track of emerging variants and new outbreaks. A new medRxiv* preprint explores the role of nanopore sequencing in this effort.

14 Jul 2021

New treatment that uses 3D printed implants could bring relief to knee osteoarthritis sufferers

Pioneering 'printed metal' procedure to create bespoke treatment for early knee osteoarthritis set to be trialled in the UK following MHRA approval.

14 Jul 2021

Researchers examine efficacy of CT-P59 monoclonal antibody against SARS-CoV-2 Brazil variant

The therapeutic monoclonal antibody CT-P59 binds to the RBD of SARS-CoV-2, the site of these three major mutations, which may therefore reduce the potency of this antibody against the P.1 lineage. In a new study, the neutralizing potency of this monoclonal antibody towards both wildtype and P.1 SARS-CoV-2 is investigated. The researchers found that the ability to bind with the virus is impeded by the mutations, resulting in reduced potency in vitro.

14 Jul 2021

High individual-level variability in SARS-CoV-2 shedding may explain superspreading

Researchers in the United States have provided a high-resolution description of the viral dynamics involved in acute infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

14 Jul 2021

Researchers receive NIH grant to explore how imaging can help predict atrial fibrillation recurrence

A team led by researchers from Cleveland Clinic and Case Western Reserve University have received a $2.95 million grant over four years from the National Institutes of Health to explore how imaging can be used to predict the risk of atrial fibrillation recurrence.

12 Jul 2021

The progressive increase in transmissibility and virulence of emerging SARS-CoV-2 variants could lead to a significantly more deadly pandemic

Researchers from Toronto University, Canada, recently showed that these emerging VOCs were linked to increased virulence, as determined by hospitalization risk, ICU admission, and mortality. This study is currently available on the medRxiv* preprint server.

12 Jul 2021

Antigen testing identifies PCR-positive children with live SARS-CoV-2

A recent study finds that antigen-based testing can reliably identify children who are infectious for SARS-CoV-2.

11 Jul 2021

Breakthrough SARS-CoV-2 infection among fully vaccinated likely to be less transmissible

Researchers in the United States have conducted a study suggesting that individuals fully vaccinated against coronavirus disease 2019 (COVID-19) who develop breakthrough infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are less likely to transmit the virus to others than unvaccinated infected individuals.

8 Jul 2021

Detailed performance evaluation of the uEXPLORER total-body PET/CT scanner

A performance evaluation of the uEXPLORER total-body PET/CT scanner showed that it exhibits ultra-high sensitivity that supports excellent spatial resolution and image quality.

8 Jul 2021

Research reveals recovery of cancer screening tests and associated disparities after first pandemic peak

The numbers of cancer screening tests rebounded sharply in the last quarter of 2020, following a dramatic decline in the first months of the COVID-19 pandemic, at one large hospital system in the Northeastern United States. These findings were released in a study published in Cancer Cell.

8 Jul 2021

B.1.427/B.1.429 variant of SARS-CoV-2 evades neutralization via disulfide bond rearrangement

A new paper discusses an intriguing new mechanism of immune evasion traceable to specific mutations in the B.1.427/B.1.429 variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

7 Jul 2021

Molecular imaging can improve therapeutic management of pancreatic ductal adenocarcinomas

For patients with pancreatic ductal adenocarcinomas (PDAC), molecular imaging can improve staging and clinical management of the disease, according to research published in the June issue of The Journal of Nuclear Medicine.

7 Jul 2021

Artificial intelligence program analyzes CT scans for tell-tale signs of prostate cancer

Prostate cancer is the most diagnosed cancer and a leading cause of death by cancer in Australian men.

7 Jul 2021

Study assesses the impact of tic suppression on brain functional connectivity in Tourette syndrome

Tourette syndrome, a neurodevelopmental disorder, causes motor and phonic "tics" or uncontrollable repeated behaviors and vocalizations. People affected by Tourette syndrome can often suppress these tics for some time before the urges become overwhelming, and researchers have long wondered at the neural underpinnings of the suppression effort.

7 Jul 2021

Study shows antibody titers after natural SARS-CoV-2 infection last longer than previously thought

A recent study by researchers from the United Kingdom (UK) revealed that antibody levels associated with protection against reinfection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are likely to last from 1.5 to 2 years on average and that the protection from severe infection may be present for several years.

7 Jul 2021

Researchers develop random priming amplification method for whole-genome sequencing of SARS-CoV-2 and H1N1

Researchers from the UK recently compared the performance of 4 different random priming amplification methods to recover SARS-CoV-2 RNA. In method 1 (H-P), the reverse transcriptase (RT) step included random hexamers, whereas, in methods 2-4, RT incorporated an octamer primer with a known tag. This study is published on the bioRxiv preprint server.

5 Jul 2021

Is there a link between circadian rhythms and COVID-19 severity?

This study showed that the time of day of SARS-CoV-2 infection could impact the severity of the viral infection and the host immune response.

1 Jul 2021

Effectively monitoring COVID-19 in reopened educational institutions: the San Diego model

An interesting new study from the University of California San Diego (UCSD) shows that using preventive measures to block viral transmission, coupled with repeated testing and rapid turnaround times for the results, can successfully prevent outbreaks associated with the reopening of educational institutions.

30 Jun 2021

Study offers more evidence that face masks can prevent SARS-CoV-2 transmission

A new study released as a preprint on the medRxiv* server suggests that the use of face masks, of various designs, successfully prevents SARS-CoV-2 transmission. This supports the continued implementation of mask policies in public places until herd immunity is achieved in the region involved.

29 Jun 2021

Advanced X-ray technology provides a viable pipeline for multiscale whole brain imaging

Researchers at the University of Chicago and the U.S. Department of Energy's (DOE) Argonne National Laboratory have leveraged existing advanced X-ray microscopy techniques to bridge the gap between MRI (magnetic resonance imaging) and electron microscopy imaging, providing a viable pipeline for multiscale whole brain imaging within the same brain.

29 Jun 2021

CT News and Research

Nanopore technology allows point-of-care SARS-CoV-2 genomic sequencing

New treatment that uses 3D printed implants could bring relief to knee osteoarthritis sufferers

Researchers examine efficacy of CT-P59 monoclonal antibody against SARS-CoV-2 Brazil variant

High individual-level variability in SARS-CoV-2 shedding may explain superspreading

Researchers receive NIH grant to explore how imaging can help predict atrial fibrillation recurrence

The progressive increase in transmissibility and virulence of emerging SARS-CoV-2 variants could lead to a significantly more deadly pandemic

Antigen testing identifies PCR-positive children with live SARS-CoV-2

Breakthrough SARS-CoV-2 infection among fully vaccinated likely to be less transmissible

Detailed performance evaluation of the uEXPLORER total-body PET/CT scanner

Research reveals recovery of cancer screening tests and associated disparities after first pandemic peak

B.1.427/B.1.429 variant of SARS-CoV-2 evades neutralization via disulfide bond rearrangement

Molecular imaging can improve therapeutic management of pancreatic ductal adenocarcinomas

Artificial intelligence program analyzes CT scans for tell-tale signs of prostate cancer

Study assesses the impact of tic suppression on brain functional connectivity in Tourette syndrome

Study shows antibody titers after natural SARS-CoV-2 infection last longer than previously thought

Researchers develop random priming amplification method for whole-genome sequencing of SARS-CoV-2 and H1N1

Is there a link between circadian rhythms and COVID-19 severity?

Effectively monitoring COVID-19 in reopened educational institutions: the San Diego model

Study offers more evidence that face masks can prevent SARS-CoV-2 transmission

Advanced X-ray technology provides a viable pipeline for multiscale whole brain imaging

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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