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Researchers develop 'flash and freeze' method for studying nerve connections

Uniting structure and function of synapses is challenging: Function is studied in living tissue, measuring electrical signals at millisecond precision with electrophysiology, while the observation of fine structure at nanometer scale requires tissue to be fixed for electron microscopy.

9 Jan 2020

Research reveals cardiac thin filament structure and function

Researchers at Osaka University used electron cryomicroscopy to image essential cardiac muscle components, known as thin filaments, with unprecedented resolution.

9 Jan 2020

New approach using deep learning could speed up brain image microscopy by 16 times

Textbook descriptions of brain cells make neurons look simple: a long spine-like central axon with branching dendrites.

8 Jan 2020

Clinical trial tests experimental stem cell treatment against best available drugs for MS

A clinical trial has begun testing an experimental stem cell treatment against the best available biologic therapies for severe forms of relapsing multiple sclerosis.

7 Jan 2020

Structure of most lethal toxin produced by C. difficile bacteria identified

Researchers from the University of Maryland School of Medicine and their colleagues have identified the structure of the most lethal toxin produced by certain strains of Clostridium difficile bacteria, a potentially deadly infection associated with the use of antibiotics. The

2 Jan 2020

Early modern humans in southern Africa cooked starchy plants 170 thousand years ago

"The inhabitants of the Border Cave in the Lebombo Mountains on the Kwazulu-Natal/eSwatini border were cooking starchy plants 170 thousand years ago," says Professor Lyn Wadley, a scientist from the Wits Evolutionary Studies Institute at the University of the Witwatersrand, South Africa.

2 Jan 2020

Study reveals key insight into the development of hair bundles

New research reveals a key insight into the development of hair bundles, the intricately complex assemblies in the inner ear responsible for hearing.

2 Jan 2020

Discovery of molecular origins of a heart beat

Researchers have found that molecular origins of a heart beat. They have found the proteins that make up tiny sodium channels in the tissues of the heart that can help generate the heart beats. The results of the study titled, “Structure of the Cardiac Sodium Channel” was published yesterday 19th of December 2019 in the journal Cell.

22 Dec 2019

A receptor helps body cells to spot communication amongst bacteria

Bacterial infection does not automatically lead to illness; many germs only become dangerous when they occur in large numbers.

20 Dec 2019

Atomic-level structure of cardiac sodium channel

Atomic-level studies of the architecture of tiny sodium channel proteins, critical to generating electrical signals that start off each beat of the heart, are imparting striking details about their function, malfunctions, disruption by many disease mutations, and response to medication.

20 Dec 2019

First images of new gene editing complex which could upgrade CRISPR

Nobel Prize-winning technique used to capture images of a new gene-editing tool that could improve CRISPR-based tools.

19 Dec 2019

Using bacterial nano-syringes as drug transporters in medicine

Pathogens can use a range of toxins to damage their host organism. Bacteria, such as those responsible for causing the deadly Plague, use a special injection mechanism to deliver their poisonous contents into the host cell.

17 Dec 2019

KAUST researchers develop electronic biosensor powered using glucose in bodily fluids

An electronic biosensor powered using the glucose in bodily fluids has been developed by KAUST researchers. The device pairs an electron-transporting polymer with an enzyme that extracts electrons from its reaction with glucose to drive its circuitry.

16 Dec 2019

Gene drives are faster, more efficient to control mosquitoes that spread malaria

When controlling mosquitoes that spread malaria, gene drives, which force genetic changes to proliferate in a population, are faster and more efficient than simply releasing mosquitoes that are immune to the parasite, according to a new study published December 19th in PLOS Genetics by Anthony James at University of California, Irvine and colleagues.

13 Dec 2019

Scientists solve 3D structure of vaccinia virus RNA polymerase

For viruses to multiply, they usually need the support of the cells they infect. In many cases, only in their host's nucleus can they find the machines, enzymes and building blocks with which they can multiply their genetic material before infecting other cells.

12 Dec 2019

Molecular drills target and destroy deadly superbugs

Molecular drills have gained the ability to target and destroy deadly bacteria that have evolved resistance to nearly all antibiotics. In some cases, the drills make the antibiotics effective once again.

12 Dec 2019

Researchers examine p53-deficient colon cancer cells to identify how p53 impacts metabolic adaptation

Colon cancer cells deficient in p53, one of the most important control proteins in cell growth, activate a particular metabolic pathway to adapt to the lack of oxygen and nutrients inside the tumor. Statins, which are often prescribed to lower cholesterol, block this metabolic pathway and cause the cancer cells to die, as scientists from the German Cancer Research Center have now discovered.

12 Dec 2019

Developments in the search for a Zika vaccine - success in mice and a new platform for flavivirus vaccines

Researchers have vaccinated mice against the Zika virus, whilst others have discovered a new platform for flavivirus vaccines.

12 Dec 2019

A recombinant platform for flavivirus vaccines and diagnostics using chimeras

A new technology to produce safer ‘hybrid’ viruses at high volumes for use in vaccines and diagnostics for mosquito-borne diseases has been developed at The University of Queensland.

11 Dec 2019

NTU scientists find potential route to disabling viruses causing severe respiratory diseases

A team of molecular and structural biologists from Nanyang Technological University, Singapore have found a potential new route to disabling respiratory syncytial virus and human metapneumovirus after elucidating the structure of one of its key components.

9 Dec 2019

Electron News and Research

Researchers develop 'flash and freeze' method for studying nerve connections

Research reveals cardiac thin filament structure and function

New approach using deep learning could speed up brain image microscopy by 16 times

Clinical trial tests experimental stem cell treatment against best available drugs for MS

Structure of most lethal toxin produced by C. difficile bacteria identified

Early modern humans in southern Africa cooked starchy plants 170 thousand years ago

Study reveals key insight into the development of hair bundles

Discovery of molecular origins of a heart beat

A receptor helps body cells to spot communication amongst bacteria

Atomic-level structure of cardiac sodium channel

First images of new gene editing complex which could upgrade CRISPR

Using bacterial nano-syringes as drug transporters in medicine

KAUST researchers develop electronic biosensor powered using glucose in bodily fluids

Gene drives are faster, more efficient to control mosquitoes that spread malaria

Scientists solve 3D structure of vaccinia virus RNA polymerase

Molecular drills target and destroy deadly superbugs

Researchers examine p53-deficient colon cancer cells to identify how p53 impacts metabolic adaptation

Developments in the search for a Zika vaccine - success in mice and a new platform for flavivirus vaccines

A recombinant platform for flavivirus vaccines and diagnostics using chimeras

NTU scientists find potential route to disabling viruses causing severe respiratory diseases

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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