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New process could fast track antiviral and anticancer drug discovery

Discovering antiviral and anticancer drugs will soon be faster and cheaper thanks to new research from Simon Fraser University chemist Robert Britton and his international team.

7 Aug 2020

Scientists find new way of identifying and targeting hidden HIV viral reservoirs during ART therapy

Scientists at The Wistar Institute may have discovered a new way of identifying and targeting hidden HIV viral reservoirs during treatment with antiretroviral therapy (ART).

7 Aug 2020

Providers participating in intervention resources are more likely to follow chronic opioid therapy guidelines

Results of a new study find that providers participating in an intervention with education and resources to help manage chronic opioid therapy for patients with HIV and chronic pain are more likely to adhere to national chronic opioid therapy guidelines compared to providers who do not take part.

7 Aug 2020

Humans promote diseases from the animal kingdom

The coronavirus pandemic, which has now infected nearly 19 million and killed more than 712,000 people, most likely originated from bats. Just like other coronavirus outbreaks in the past, a spill-over event or zoonosis caused the viruses to jump from animals to humans.

6 Aug 2020

Frequent HIV screenings can benefit high-risk young men who have sex with men

A new study has found that HIV screening every three months compared to annually will improve clinical outcomes and be cost-effective among high-risk young men who have sex with men (YMSM) in the United States.

6 Aug 2020

American Lung Association launches first monthly pulmonary podcast series

Today, the American Lung Association is launching its first monthly podcast series, called Lungcast.

6 Aug 2020

New automated cytometry test for rapid point-of-care cancer diagnosis

Scientists have created a rapid and affordable test for breast cancer that is designed for use in developing regions, where patients often face delayed diagnoses that worsen their outcomes.

5 Aug 2020

A SARS-CoV-2 assay using plant proteins

Researchers in South Africa have developed a serological assay that readily detects antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) using recombinant viral proteins produced in plants.

5 Aug 2020

Avidity of binding responsible for cross-neutralization of SARS-CoV-1 and SARS-CoV-2

In a new study published on the preprint server bioRxiv researchers characterized the crystal structure of the antibody-SARS-CoV-2 RBD complex in an attempt to find the epitope and the mechanism that enables cross-neutralization.

5 Aug 2020

ACTG initiates novel clinical trial to evaluate multiple therapeutics for COVID-19

The AIDS Clinical Trials Group, the world's largest and longest established HIV research network, today announced the initiation of the ACTIV-2 Outpatient Monoclonal Antibodies and Other Therapies Trial, which will be conducted by the ACTG.

4 Aug 2020

Clinical trial to test safety, efficacy of antibody treatment in hospitalized COVID-19 patients

Patients admitted with COVID-19 at select hospitals may now volunteer to enroll in a clinical trial to test the safety and efficacy of a potential new treatment for the disease.

4 Aug 2020

Normal DNA repair process can lead to mutations in cancer

Hypermutation is an unusual occurence that can lead to many nearby mutations at once, severely damaging our genetic material and potentially causing cancer.

4 Aug 2020

Estrogen modestly protective against COVID-19?

Almost from the beginning, scientists have been struck by the disproportionately higher numbers of men and older adults who have developed severe COVID-19 disease compared to younger individuals and women. Prior research has shown that in 37 of the 38 countries from which sex-stratified data was available, males were at a higher risk of death. Also, post-menopausal women are at increased risk of severe COVID-19. However, the biological underpinnings of this have been less visible.

4 Aug 2020

Penis microbiome is reservoir for bacterial vaginosis-associated bacteria

Previous studies have pointed out that the reproductive microbiomes of partners might be exchanged in bacterial vaginosis (BV). Now, a team of researchers at the University of Illinois in Chicago compared the microbiota of couples before and after the development of BV.

4 Aug 2020

Study shows high SARS-CoV-2 seroprevalence, but low death rate in Malawi's health care workers

A study by researchers from Malawi and United Kingdom reveals a significant discrepancy between predicted coronavirus disease (COVID-19) mortality in the observed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroprevalence rates in health care workers and reported deaths in urban Malawi in southeastern Africa, indicating early exposure, but a slow progression of the outbreak. Their findings are currently available on the medRxiv preprint server.

3 Aug 2020

SARS-CoV-2 lured away and trapped by a new decoy version of ACE2

Researchers in the United States and Canada have engineered affinity-optimized “receptor traps” that prevent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from binding to and infecting cells.

3 Aug 2020

Stabilized prefusion spike vaccine candidate induces powerful immune response

A new research paper by scientists at Janssen Vaccines & Prevention BV, in the Netherlands and published on the preprint server bioRxiv* is based on the assumption that an effective vaccine against these infections will induce neutralizing antibodies and an immune response favoring Th1 immunity.

3 Aug 2020

SARS-CoV-2 spike protein recognized by innate immune receptors in a glycan-dependent way

The spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) depends on its ability to infect new host cells following its replication and release from infected cells. This pivots on its ability to bind to cell surface receptors like the ACE2 enzyme.

3 Aug 2020

There could be 7 million unplanned pregnancies because of COVID-19

The coronavirus pandemic has rippled across the globe, infecting nearly 18 million individuals worldwide to date. Though the coronavirus disease (COVID-19) affects people from all walks of life, women and girls may experience devastating effects of the outbreak.

2 Aug 2020

War of sugars - estrogen provides protection in COVID-19

Now a new study published on the preprint server bioRxiv in July 2020 reports that sex hormones could affect the function of the fusion protein that is dependent upon the human ACE2 receptor, thus preventing the entry of the virus into the host cell.

31 Jul 2020

HIV 1 News and Research

New process could fast track antiviral and anticancer drug discovery

Scientists find new way of identifying and targeting hidden HIV viral reservoirs during ART therapy

Providers participating in intervention resources are more likely to follow chronic opioid therapy guidelines

Humans promote diseases from the animal kingdom

Frequent HIV screenings can benefit high-risk young men who have sex with men

American Lung Association launches first monthly pulmonary podcast series

New automated cytometry test for rapid point-of-care cancer diagnosis

A SARS-CoV-2 assay using plant proteins

Avidity of binding responsible for cross-neutralization of SARS-CoV-1 and SARS-CoV-2

ACTG initiates novel clinical trial to evaluate multiple therapeutics for COVID-19

Clinical trial to test safety, efficacy of antibody treatment in hospitalized COVID-19 patients

Normal DNA repair process can lead to mutations in cancer

Estrogen modestly protective against COVID-19?

Penis microbiome is reservoir for bacterial vaginosis-associated bacteria

Study shows high SARS-CoV-2 seroprevalence, but low death rate in Malawi's health care workers

SARS-CoV-2 lured away and trapped by a new decoy version of ACE2

Stabilized prefusion spike vaccine candidate induces powerful immune response

SARS-CoV-2 spike protein recognized by innate immune receptors in a glycan-dependent way

There could be 7 million unplanned pregnancies because of COVID-19

War of sugars - estrogen provides protection in COVID-19

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