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Scientists identify genetic clues linking air pollution to neurodegeneration

This review highlights how air pollution and occupational inhalation exposures may contribute to neurodegenerative disorders by triggering epigenetic changes. The authors stress the urgent need for advanced research to identify early biomarkers and guide protective health strategies for high-risk populations.

6 Jun 2025

New Japanese database reveals how gut microbes and diet connect

Researchers have launched the NIBN Japan Microbiome Database, featuring over 2,000 gut microbiome profiles from healthy Japanese adults with extensive lifestyle and dietary metadata. This resource aims to accelerate microbiome-health research and enable precision medicine insights.

5 Jun 2025

New biological age clock estimates how well someone is aging

A team of international researchers has developed a new biological age "clock" that estimates how well someone is aging, not just how "old" they or their various organs might be.

5 Jun 2025

New anti-aging compounds found hidden beneath the skin

People go to great lengths to maintain youthful-looking skin with masks, creams and serums. Now, researchers have discovered compounds with anti-aging properties hidden beneath our own skin.

5 Jun 2025

SIRT6 identified as a critical safeguard of spinal disc health

Low back pain is the most prevalent musculoskeletal condition worldwide and is closely tied to the progressive degeneration of intervertebral discs.

5 Jun 2025

Dog exposure may lower genetic risk of eczema in children

New research published in Allergy indicates that certain environmental exposures may affect a child's risk of developing atopic eczema, a condition characterized by dry, itchy, and inflamed skin. In other words, although some people may be genetically predisposed to eczema, certain environmental factors may increase or decrease that risk.

5 Jun 2025

Genetic mutation identified as key factor in immunotherapy resistance for melanoma

Tests in 1,225 patients with the most deadly form of skin cancer reveal for the first time a genetic trait among most of those who did not respond to the latest cancer treatments, known as immune checkpoint inhibitors.

5 Jun 2025

Nicotinamide riboside shows promise in treating Werner syndrome symptoms

Werner syndrome (WS) is a rare genetic disorder that causes premature aging and serious complications. In the first clinical trial of its kind, researchers from Japan with the company Niagen Bioscience, investigated the effects of nicotinamide riboside (NR), a vitamin B3 derivative, in patients with WS.

5 Jun 2025

New data shows zigakibart sustains proteinuria remission and kidney function in IgA nephropathy

New 100-week data from the ongoing Phase 1/2 study of zigakibart, an investigational anti-APRIL monoclonal antibody, reinforce its potential as a disease-modifying treatment for IgA nephropathy (IgAN).

5 Jun 2025

Type 2 diabetes drug shows improvements for patients with progressive liver disease

The sodium glucose cotransporter 2 (SGLT-2) inhibitor drug dapagliflozin, widely used to treat type 2 diabetes, also shows improvements for patients with progressive liver disease, finds a clinical trial from China published by The BMJ today.

5 Jun 2025

Gene editing can trigger inflammatory, senescence-like responses in blood stem cells

Scientists at the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), Milan, have found that gene editing using CRISPR-Cas9 in combination with AAV6 vectors can trigger inflammatory and senescence-like responses in blood stem cells, compromising their long-term ability to regenerate the blood system.

5 Jun 2025

Common antibiotic shows promise in reducing preterm births

A study of almost 1000 pregnant women in Zimbabwe found that a daily dose of a commonly used, safe and inexpensive antibiotic may have led to fewer babies being born early.

5 Jun 2025

Back-to-basics, 'not fad' diets beat heart disease and diabetes

This review examines dietary interventions that can improve cardiometabolic health, highlighting the role of whole foods in reducing heart disease and diabetes.

4 Jun 2025

Integrating discoveries with translational science to transform Alzheimer's care

At the 12th annual Helen and Robert Appel Alzheimer's Disease Research Institute Symposium, scientists and clinicians shared their latest research which is advancing how Alzheimer's disease is diagnosed and treated.

4 Jun 2025

Household environments may affect the likelihood of children developing eczema

Household environments, including owning a dog, may affect the likelihood of children developing eczema, according to an analysis of almost 300,000 people from across Europe.

4 Jun 2025

New family of antibiotics derived from the body's own proteins

A team of scientists led by the UAB has identified a new type of antimicrobial peptides (AMPs) found in human proteins that are capable of selectively eliminating multidrug-resistant bacteria, particularly of the gram-negative type, responsible for serious hospital acquired infections.

4 Jun 2025

Early contact with pet dogs protects genetically susceptible children from eczema

Having a dog at home could help to prevent eczema in children who are genetically prone to the condition, a study suggests.

4 Jun 2025

Does lithium offer hope for long COVID brain fog and fatigue? New trial gives mixed results

A randomized clinical trial found that low-dose lithium aspartate did not improve cognitive dysfunction or fatigue in long COVID patients. Higher doses showed possible benefits in a small exploratory substudy, but larger trials are needed.

4 Jun 2025

ADHD linked to higher risk of irritable bowel syndrome, global study reveals

A global meta-analysis found that people with ADHD are significantly more likely to have irritable bowel syndrome (IBS), while the overall risk for other intestinal disorders is not increased. The findings highlight the importance of gut-brain interactions in ADHD and call for further research on microbiome-based therapies.

3 Jun 2025

Navigating the dual role of B cells in tumor immunity

B lymphocytes exhibit dual roles in tumorigenesis, acting as both allies and adversaries in the tumor microenvironment (TME).

3 Jun 2025

Inflammation News and Research

Scientists identify genetic clues linking air pollution to neurodegeneration

New Japanese database reveals how gut microbes and diet connect

New biological age clock estimates how well someone is aging

New anti-aging compounds found hidden beneath the skin

SIRT6 identified as a critical safeguard of spinal disc health

Dog exposure may lower genetic risk of eczema in children

Genetic mutation identified as key factor in immunotherapy resistance for melanoma

Nicotinamide riboside shows promise in treating Werner syndrome symptoms

New data shows zigakibart sustains proteinuria remission and kidney function in IgA nephropathy

Type 2 diabetes drug shows improvements for patients with progressive liver disease

Gene editing can trigger inflammatory, senescence-like responses in blood stem cells

Common antibiotic shows promise in reducing preterm births

Back-to-basics, 'not fad' diets beat heart disease and diabetes

Integrating discoveries with translational science to transform Alzheimer's care

Household environments may affect the likelihood of children developing eczema

New family of antibiotics derived from the body's own proteins

Early contact with pet dogs protects genetically susceptible children from eczema

Does lithium offer hope for long COVID brain fog and fatigue? New trial gives mixed results

ADHD linked to higher risk of irritable bowel syndrome, global study reveals

Navigating the dual role of B cells in tumor immunity

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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