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Study of pan-FGFR inhibitor uses mRNA in tumours to identify responders

The first-in-human dose escalation study of the pan-FGFR (fibroblast growth factor receptor) inhibitor BAY 1163877 in patients with treatment-refractory locally advanced or metastatic solid tumours were reported today at the ESMO 2016 Congress in Copenhagen.

8 Oct 2016

New tool helps measure how costs of care impact cancer patients

For many patients, the uncertainty and stress that can come with cancer treatment is compounded by what is now known as "financial toxicity," the anxiety and distress that follow health care and medication expenses, often compounded by reduced ability to work.

7 Oct 2016

New study questions longstanding belief related to hemodialysis patients treated with catheters

The findings of a new study call into question the longstanding belief that the higher risk of premature death seen in hemodialysis patients who are treated with catheters is due to an elevated risk of complications.

7 Oct 2016

Japanese researchers discover causative gene for common type of hearing loss

A causative gene for a highly common type of hearing loss (sensorineural hearing loss, or SNHL) has been identified by a group of Japanese researchers, who successfully replicated the condition using a transgenic mouse.

6 Oct 2016

Increasing incidence of thyroid cancer in past three decades

The incidence of thyroid cancer has tripled in the past three decades, yet the reason for this is not clear.

6 Oct 2016

IMRT linked to reduced xerostomia and feeding tube dependency in oropharyngeal cancer patients

Radiation therapy is the main treatment modality in the management of head and neck cancer.

4 Oct 2016

Graded aerobic treadmill testing safe, tolerable in young patients with sports-related concussion

Graded aerobic treadmill testing is safe, tolerable, and useful in evaluating and managing cases of sports-related concussion in children and adolescents.

3 Oct 2016

Mouthguards may help improve performance of athletes

Could mouthguards improve athletic performance? Yes, mouthguards protect your teeth during sports. But they may do much more for athletes, from improving performance to shielding the brain from the effects of contact sports.

30 Sep 2016

Specific HPV strain linked to better overall survival for oropharyngeal cancer patients

When it comes to cancer-causing viruses like human papillomavirus, or HPV, researchers are continuing to find that infection with one strain may be better than another.

28 Sep 2016

Aflatoxin exposure can weaken airways' defenses opening door for severe respiratory diseases

Toxins from mold found growing on nuts or corn can weaken the airways' self-clearing mechanisms and immunity, opening the door for respiratory diseases and exacerbating existing ones, suggests a study in Nature Scientific Reports published this month from otolaryngology researchers at the Perelman School of Medicine at the University of Pennsylvania.

27 Sep 2016

Approval of PD-1 inhibitor scratches surface of potential immunotherapies in recurrent HNSCC

The recent approval of pembrolizumab (Keytruda) in recurrent or metastatic head and neck squamous cell carcinoma (HNSCC) following progression on a platinum-based chemotherapy was a significant advancement for the disease.

26 Sep 2016

Scientist develops way to detect BoNT in biological samples

Many know Botox as a trendy way to get rid of wrinkles, but the popular drug — made from botulinum neurotoxin (BoNT) — can do more than just fill lines.

23 Sep 2016

Precision medicine trial shows analysing person's DNA improves treatment options for cancer patients

A clinical trial for types of advanced cancer is the first of its kind to show that precision medicine - or tailoring treatment for individual people - can slow down the time it takes for a tumour to grow back, according to research presented at the Molecular Analysis for Personalised Therapy (MAP) conference, today (Friday).

23 Sep 2016

New open access journal covers latest research on diseases affecting the head and neck areas

The American Academy of Otolaryngology—Head and Neck Surgery Foundation is pleased to announce that OTO Open, the Academy's new and official open access journal will be joining the Academy's premier journal, Otolaryngology—Head and Neck Surgery, both published by SAGE Publishing.

21 Sep 2016

Mount Sinai and TJU researchers awarded grant for UM research

Uveal melanoma (UM) is the second most common type of skin cancer. Approximately 50 percent of patients will develop metastasis or spread of their cancer, most commonly to the liver.

21 Sep 2016

Sanford wins $11.7 million NIH grant to translate laboratory cancer research into clinical trials

The Cancer Biology Research Center at Sanford Research is the recipient of a five-year, nearly $11.7 million grant from the National Institutes of Health to translate laboratory research into clinical trials for head and neck and pediatric cancers.

20 Sep 2016

Researchers discover gene variants linked to thoracic aortic dissections

On Super Bowl Sunday, Tina Wilkins was relaxing in her recliner while she chatted on the phone with her mother and waited for the game to begin. She had recently lost 63 pounds and was in better shape than she had been in years.

20 Sep 2016

TransOral Robotic Surgery may provide good outcomes, survival for oropharyngeal cancer patients

A new study from researchers at Henry Ford Hospital finds an incisionless robotic surgery - done alone or in conjunction with chemotherapy or radiation - may offer oropharyngeal cancer patients good outcomes and survival, without significant pain and disfigurement.

16 Sep 2016

Noise levels in nightclubs may induce hearing loss

A new study raises concerns about the noise level in nightclubs. Researchers in Southern California have found that the average continuous level of noise in some nightclubs is at least 91.2 dBA (A-weighted decibels).