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Research into cellular senescence may lead to new ways of treating age-related disorders

One of the things that happens to our bodies as we age is that certain cells start to accumulate. So-called senescent cells – cells that "retire" and stop dividing but refuse to die – are always present, and they even serve some important functions, such as in wound repair.

18 May 2017

Researchers visualize precise mechanisms of calcium-dependent kinase during synaptic plasticity

Researchers at Max Planck Florida Institute for Neuroscience optimized imaging methods to visualize the activation of CaMKII during synaptic plasticity with unprecedented resolution.

18 May 2017

FDA-approved drug improves clinical outcomes among patients with rare immunologic disease

Adding the injectable drug mepolizumab to standard treatment for eosinophilic granulomatosis with polyangiitis (EGPA), a rare immunologic disease, significantly improved clinical outcomes among participants in an advanced clinical trial, scientists report.

18 May 2017

Biochemical self-destruct trigger guards brain cells when fighting against West Nile virus

In a turnabout, a biochemical self-destruct trigger found in many other types of cells appears to guard the lives of brain cells during an infection with West Nile virus.

18 May 2017

Research paves way for safer and more effective drugs to treat type 2 diabetes

Research led by the University of Adelaide is paving the way for safer and more effective drugs to treat type 2 diabetes, reducing side effects and the need for insulin injections.

18 May 2017

FDA warns Americans about inaccurate lead testing in children and mothers

The U.S. Food and Drug Administration and Centers for Disease Control and Prevention are warning Americans that certain lead tests manufactured by Magellan Diagnostics may provide inaccurate results for some children and adults in the United States.

18 May 2017

FDA expands approval for cystic fibrosis drug to treat additional rare gene mutations

The U.S. Food and Drug Administration today expanded the approved use of Kalydeco (ivacaftor) for treating cystic fibrosis.

18 May 2017

University of Warwick research focuses on absence epilepsy that affects children

A University of Warwick study to understand a form of epilepsy that affects children has received a grant from the charity Epilepsy Research UK. The research focuses on absence epilepsy which is largely a childhood condition which is characterized by sudden, brief interruptions of consciousness.

18 May 2017

Opioid prescription for minor injuries increases risk of continued use and addiction

Overprescribing of opioid medications for pain has contributed to a record-high number of drug-related deaths in the United States in recent years.

18 May 2017

DAWN trial: Mechanical thrombectomy plus medication significantly decreases post-stroke disability

Results from the DAWN stroke trial presented at the European Stroke Organization Conference provide compelling evidence that selected patients suffering a major ischemic stroke recovered significantly better with mechanical retrieval of the blood clot with medical therapy compared with medical therapy alone when initiated past the current guidelines of within 6 hours and up to 24 hours of the stroke.

18 May 2017

Study highlights need to improve calcium and vitamin D intake in pediatric IBD patients

A new study highlights that children suffering from inflammatory bowel disease are not meeting the daily recommended intake of calcium and vitamin D. The research, conducted at Great Ormond Street Hospital for Children in London, identified that only 26.6% and 21.3% of paediatric IBD patients were achieving the current recommended intake for calcium and vitamin D respectively.

18 May 2017

MR Solutions to showcase latest MRI imaging technology at World Preclinical Congress in Boston

MR Solutions, with offices in the UK and Boston, will be showing their latest state of the art 3T to 9.4T superconducting, cryogen-free MRI imaging technology with optional PET and SPECT imaging modalities on stand 407 at the 16th annual World Preclinical Congress in Boston on June 13th to 15th. The congress focusses on the very latest trends and technologies impacting the preclinical drug discovery and development world.

18 May 2017

Researchers explore new treatment combination for pediatric patients with Hodgkin lymphoma

Pediatric and young adult patients whose Hodgkin lymphoma has recurred or is resistant to initial treatment can achieve remission and even cure with secondary treatments.

18 May 2017

Researchers identify DNA repair deficiency in many types of solid tumors

A new investigation of more than 48,000 stored tumor samples finds evidence of a key deficiency in a repair mechanism designed to keep DNA from being mutated and causing cancer.

18 May 2017

Self-treated pain can contribute to risk of frequent non-medical prescription opioid use

Physical pain--often "self-medicated" without help from healthcare professionals--is an important contributor to non-medical prescription opioid (NMPO) use by young adults, suggests a study in the Journal of Addiction Medicine, the official journal of the American Society of Addiction Medicine.

17 May 2017

Brisbane researchers synthetically re-create Zika virus to better understand birth defects

Brisbane researchers have synthetically re-created Zika virus in the laboratory - a breakthrough which will help to understand the virus and the fetal brain defects it causes.

17 May 2017

Researchers identify new drug target for two common types of myeloid leukemia

University of Georgia researchers, with colleagues from the University of Tokyo, have identified a new drug target for the two most common types of myeloid leukemia, including a way to turn back the most aggressive form of the disease.

17 May 2017

University of Guelph researcher discovers effective way to treat shortness of breath in heart failure

Shortness of breath is the No.1 complaint of people suffering from heart failure. Now a University of Guelph researcher has discovered its surprising cause - and an effective treatment - in a groundbreaking new study.

17 May 2017

Study reveals that large number of people in the U.S. drink at very high levels

Nearly 32 million adults in the United States (13 percent of the U.S. population aged 18 and older) consumed more than twice the number of drinks considered binge drinking on at least one occasion, according to a 2013 survey that asked about past-year drinking.

17 May 2017

Scientists identify gene linked to incurable bowel disorders

A key gene that helps to explain an underlying cause of incurable bowel disorders such as Crohn's disease has been identified by scientists.

17 May 2017

Drugs News and Research

Research into cellular senescence may lead to new ways of treating age-related disorders

Researchers visualize precise mechanisms of calcium-dependent kinase during synaptic plasticity

FDA-approved drug improves clinical outcomes among patients with rare immunologic disease

Biochemical self-destruct trigger guards brain cells when fighting against West Nile virus

Research paves way for safer and more effective drugs to treat type 2 diabetes

FDA warns Americans about inaccurate lead testing in children and mothers

FDA expands approval for cystic fibrosis drug to treat additional rare gene mutations

University of Warwick research focuses on absence epilepsy that affects children

Opioid prescription for minor injuries increases risk of continued use and addiction

DAWN trial: Mechanical thrombectomy plus medication significantly decreases post-stroke disability

Study highlights need to improve calcium and vitamin D intake in pediatric IBD patients

MR Solutions to showcase latest MRI imaging technology at World Preclinical Congress in Boston

Researchers explore new treatment combination for pediatric patients with Hodgkin lymphoma

Researchers identify DNA repair deficiency in many types of solid tumors

Self-treated pain can contribute to risk of frequent non-medical prescription opioid use

Brisbane researchers synthetically re-create Zika virus to better understand birth defects

Researchers identify new drug target for two common types of myeloid leukemia

University of Guelph researcher discovers effective way to treat shortness of breath in heart failure

Study reveals that large number of people in the U.S. drink at very high levels

Scientists identify gene linked to incurable bowel disorders

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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