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Researchers develop new test for rapid and reliable diagnosis of sepsis

Researchers have developed a test that can rapidly and reliably diagnose sepsis, a potentially life-threatening complication of bacterial infections.

17 May 2017

History of sleep: what was normal?

We used to sleep in two phases, with a first sleep and then a second sleep. Arguably from time immemorial to the nineteenth century, the dominant pattern of sleep in Western societies was biphasic, whereby most preindustrial households retired between 9 and 10pm, slept for 3 to 3 ½ hours during their “first sleep,”

17 May 2017

‘Disease in a dish’ model pinpoints how defects in blood-brain barrier can cause psychomotor disorder

Scientists for the first time have assembled a "disease in a dish" model that pinpoints how a defect in the blood-brain barrier can produce an incurable psychomotor disorder, Allan-Herndon-Dudley syndrome.

17 May 2017

Neurobiologists uncover reason for defects in the blood-brain barrier of Huntington's disease patients

By using induced pluripotent stem cells to create endothelial cells that line blood vessels in the brain for the first time for a neurodegenerative disease, University of California, Irvine neurobiologists and colleagues have learned why Huntington's disease patients have defects in the blood-brain barrier that contribute to the symptoms of this fatal disorder.

17 May 2017

Scientists use AHDS patients’ cells to recreate disease and mimic blood-brain barrier

The blood-brain barrier is biology's proverbial double-edged sword. An impermeable shield of endothelial cells that protects our brains from toxins and other threats that may lurk in circulating blood, the barrier can also exclude therapeutic drugs and, at times, essential biomolecules required for healthy brain development.

17 May 2017

New research could be first step toward drug to treat Zika infections

New research led by Alexey Terskikh, Ph.D., associate professor at Sanford Burnham Prebys Medical Discovery Institute (SBP), and Alex Strongin, Ph.D., professor at SBP, could be a first step toward a drug to treat Zika infections. Publishing in Antiviral Research, the scientific team discovered a compound that prevents the virus from spreading.

16 May 2017

Researchers identify many dangerous strains of TB pathogens

Researchers from the Vavilov Institute of General Genetics of the Russian Academy of Sciences (VIGG) and the Moscow Institute of Physics and Technology have established a catalog of mutations in 319 virulence genes of mycobacteria that cause tuberculosis.

16 May 2017

EPFL scientists develop new antibody-linked biosensor to track drug concentration in the blood

Being able to monitor drug concentration in the blood of a patient is an important aspect of any pharmaceutical treatment. However, this requires equipment and facilities that are often missing from field healthcare in developing countries, but also inhibits the quality of life for patients elsewhere.

16 May 2017

Study provides vital clues to counter superbug antibiotic resistance

An international study led by Monash University has discovered the molecular mechanism by which the potentially deadly superbug 'Golden Staph' evades antibiotic treatment, providing the first important clues on how to counter superbug antibiotic resistance.

16 May 2017

Making brain implants smaller could eliminate scarring, extend life of devices

Many diseases, including Parkinson's disease, can be treated with electrical stimulation from an electrode implanted in the brain. However, the electrodes can produce scarring, which diminishes their effectiveness and can necessitate additional surgeries to replace them.

16 May 2017

Prototype drug prevents lung cancer tumors in mice by using novel mechanism

Lung cancer tumors were prevented in mice by a novel small molecule that directly activates a tumor suppressor protein.

16 May 2017

UB researchers explore potential side effects of stimulant drug on people without ADHD

New research from the University at Buffalo Research Institute on Addictions that explored the potential side effects of the stimulant drug Ritalin on those without ADHD showed changes in brain chemistry associated with risk-taking behavior, sleep disruption and other undesirable effects.

16 May 2017

Research identifies protein that could help patients respond more positively to epilepsy drug therapies

New research from the University of Liverpool, in collaboration with the Mario Negri Institute in Milan, published today in the Journal of Clinical Investigation, has identified a protein that could help patients with epilepsy respond more positively to drug therapies.

16 May 2017

Drugs News and Research

Researchers develop new test for rapid and reliable diagnosis of sepsis

History of sleep: what was normal?

‘Disease in a dish’ model pinpoints how defects in blood-brain barrier can cause psychomotor disorder

Neurobiologists uncover reason for defects in the blood-brain barrier of Huntington's disease patients

Scientists use AHDS patients’ cells to recreate disease and mimic blood-brain barrier

New research could be first step toward drug to treat Zika infections

Researchers identify many dangerous strains of TB pathogens

EPFL scientists develop new antibody-linked biosensor to track drug concentration in the blood

Study provides vital clues to counter superbug antibiotic resistance

Making brain implants smaller could eliminate scarring, extend life of devices

Prototype drug prevents lung cancer tumors in mice by using novel mechanism

UB researchers explore potential side effects of stimulant drug on people without ADHD

Research identifies protein that could help patients respond more positively to epilepsy drug therapies

WSU scientists develop new approach to deliver therapeutics to tumors

Composition, function of intestinal bacteria could predict response to biologic drugs in IBD patients

IBM scientists identify new way to trigger the body's immune response to fight diseases

UAH researcher develops new suite of phone apps to monitor physical mobility, stability of older people

Study provides insights into how HCMV infection causes birth defects

Researchers highlight need to ensure universal access to old antibiotics

Scientists uncover potential strategy to shock and kill HIV virus

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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