Bone News and Research

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High blood pressure may cause bones to age faster

When high blood pressure was induced in young mice, they had bone loss and osteoporosis-related bone damage comparable to older mice, according to new research presented today at the American Heart Association's Hypertension Scientific Sessions 2022 conference, held Sept. 7-10, 2022, in San Diego.

7 Sep 2022

New CT technology paired with deep learning denoising enables better detection of multiple myeloma bone disease

New CT technology paired with artificial intelligence (AI)-based noise reduction offers superior detection of bone disease associated with multiple myeloma at lower radiation doses than conventional CT, according to a new study published in Radiology, a journal of the Radiological Society of North America.

6 Sep 2022

Study investigates the effect of vitamin D and fish oil on croup

Babies and children under three years old are less likely to develop croup if their mothers took fish oil and vitamin D supplements during pregnancy, according to new results from a clinical trial. The findings are from a randomised controlled trial – the 'gold standard' for medical research – that will be presented at the European Respiratory Society International Congress in Barcelona, Spain. It is the first large study of its kind to investigate the effects of vitamin D and fish oil on croup.

5 Sep 2022

Immune cells beyond CAR-T cells affect the durability of response to BCMA CAR T therapy in myeloma

Patients with myeloma whose tumor immune microenvironments had a more diverse baseline T-cell repertoire, fewer markers of immune cell exhaustion, and distinct changes to immune cell populations were more likely to have longer progression-free survival (PFS) after treatment with BCMA-targeted T-cell therapy.

30 Aug 2022

Vitamin D mediates crosstalk between COVID-19 and osteoporosis

Researchers identify and characterize the targets of Vit D on COVID-19 and osteoporosis.

30 Aug 2022

$Initial period of strict bed rest can be beneficial for older with osteoporotic vertebral fractures$

Initial period of strict bed rest can be beneficial for older with osteoporotic vertebral fractures

Aging is universal. Both osteoporosis and the bone fractures that occur as a result of osteoporosis become more likely with age.

30 Aug 2022

New scaffold supports the growth of new bone in large jaw defects in mice

Tohoku University scientists in Japan have made a scaffold that supports the growth of new bone in large jaw defects in mice.

30 Aug 2022

New advice aims to reduce the cardiac side effects of cancer treatment

The first European Society of Cardiology Guideline on cardio-oncology is published online today in European Heart Journal.

26 Aug 2022

CU professor explores for noninvasive ways to detect vascularized composite allograft rejection

Soldiers and others who receive severe injuries to the hands and face often can benefit from a type of transplant known as vascularized composite allograft (VCA) - the transplantation of multiple tissues, including muscle, bone, nerve, skin, and blood vessels, as a functional unit (such as a hand or face) from a deceased donor to a recipient with a severe injury.

25 Aug 2022

How does the human gut microbiome impact menopause?

A recent study summarizes available information on the relationship between menopause and the gut microbiome.

24 Aug 2022

Researchers discover a new class of more potent and less toxic drugs for leukemia patients

Chemotherapy sucks. The treatments generally have awful side effects, and it's no secret that the drugs involved are often toxic to the patient as well as their cancer.

24 Aug 2022

Researchers identify a potential new therapeutic approach to fight angioimmunoblastic T-cell lymphoma

A type of blood cell cancer called angioimmunoblastic T-cell lymphoma (AITL) can develop as mutations accumulate with age in the stem cells from which the T cells in the blood develop.

24 Aug 2022

Insights into the biology of the monkeypox virus

Researchers provided insights into monkeypox virus structural characteristics, epidemiology, transmission, zoonotic reservoirs, pathogenesis, and clinical management.

23 Aug 2022

High levels of stress hormones can stop bone growth in children

As we go through life, our health and wellbeing is impacted by a variety of factors that in turn affect our growth and development.

23 Aug 2022

New resource can help researchers to assess how key genes control the differentiation of developing embryos

Years of work by developmental biologists from Trinity College Dublin, working with colleagues at the University of Edinburgh's MRC Human Genetics Unit, has yielded a resource of unparalleled detail that will help researchers assess how key genes control the differentiation of tissues and organs of developing embryos.

19 Aug 2022

$Elevated blood levels of certain chemokine linked with higher hip fracture risk in men$

Elevated blood levels of certain chemokine linked with higher hip fracture risk in men

Bone health requires a balanced activity of various bone cell types including bone-forming osteoblasts and bone-resorbing osteoclasts.

17 Aug 2022

New anti-cancer drug candidate is absorbed through the lymphatic system rather than blood vessels

A team of University of Michigan researchers is developing a new anti-cancer drug that is absorbed through the gut's lymphatic system rather than blood vessels, potentially outmaneuvering the molecular signaling pathways that lead to drug resistance while increasing cancer-fighting ability and reducing side effects.

17 Aug 2022

$Chemokines likely to be associated with the risk of osteoporotic hip fracture in older men$

Chemokines likely to be associated with the risk of osteoporotic hip fracture in older men

Bone health requires a balanced activity of various bone cell types including bone-forming osteoblasts and bone-resorbing osteoclasts. Osteoporosis occurs when osteoclasts dominate without adequate bone formation to compensate. In new research published in the Journal of Bone and Mineral Research, elevated blood levels of a certain chemokine, or small signaling protein, that promotes osteoclast formation were linked with a higher risk of hip fracture in men.

17 Aug 2022

Peter Adams and Bing Ren receive NIH grant to join multi-institution initiative studying the aging process

Peter Adams, Ph.D., and Bing Ren, Ph.D., have been awarded a new grant from the National Institutes of Health (NIH) to join a multi-institution initiative studying the process of aging.

16 Aug 2022

KAUST bioscientists develop new method to study the bone marrow microenvironment in greater detail

Deep molecular analysis of the bone marrow microenvironment reveals that the cells regulating blood stem cell maintenance are more diverse than expected and have features likely to be conserved between species.

16 Aug 2022

Bone News and Research

High blood pressure may cause bones to age faster

New CT technology paired with deep learning denoising enables better detection of multiple myeloma bone disease

Study investigates the effect of vitamin D and fish oil on croup

Immune cells beyond CAR-T cells affect the durability of response to BCMA CAR T therapy in myeloma

Vitamin D mediates crosstalk between COVID-19 and osteoporosis

Initial period of strict bed rest can be beneficial for older with osteoporotic vertebral fractures

New scaffold supports the growth of new bone in large jaw defects in mice

New advice aims to reduce the cardiac side effects of cancer treatment

CU professor explores for noninvasive ways to detect vascularized composite allograft rejection

How does the human gut microbiome impact menopause?

Researchers discover a new class of more potent and less toxic drugs for leukemia patients

Researchers identify a potential new therapeutic approach to fight angioimmunoblastic T-cell lymphoma

Insights into the biology of the monkeypox virus

High levels of stress hormones can stop bone growth in children

New resource can help researchers to assess how key genes control the differentiation of developing embryos

Elevated blood levels of certain chemokine linked with higher hip fracture risk in men

New anti-cancer drug candidate is absorbed through the lymphatic system rather than blood vessels

Chemokines likely to be associated with the risk of osteoporotic hip fracture in older men

Peter Adams and Bing Ren receive NIH grant to join multi-institution initiative studying the aging process

KAUST bioscientists develop new method to study the bone marrow microenvironment in greater detail

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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