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Researchers seek to identify the role of hypoxia on red blood cell aging

Red blood cells are the most abundant cell type in blood, carrying oxygen throughout the human body. In blood circulation, they repetitively encounter various levels of oxygen tension.

22 Sep 2021

Nemours receives $10.5 million NIH grant to support research in sickle cell disease

Researchers at Nemours Children's Health, Delaware have received a $10.5 million National Institutes of Health grant to support the Delaware Comprehensive Sickle Cell Research Program.

21 Sep 2021

Those undergoing treatment for hematological malignancies show reduced immune response to COVID-19 vaccines

Researchers recently investigated the effect of infection with SARS-CoV-2 in patients with hematologic malignancies in minority populations.

21 Sep 2021

New evidence confirms the efficacy of COVID-19 vaccination in cancer patients

The long-awaited confirmation of the efficacy of COVID-19 vaccination in patients with cancer has arrived, on time to be disseminated to a global audience at the annual congress of the European Society for Medical Oncology (ESMO Congress 2021), the leading professional society for medical oncology.

20 Sep 2021

Sunitinib extends progression-free survival in patients with rare neuroendocrine tumor, study shows

The first randomized study in malignant pheochromocytoma and paraganglioma (MPP) has found that sunitinib prolongs progression-free survival (PFS) by more than five months.

20 Sep 2021

I got a ‘mild’ breakthrough case. Here’s what I wish I’d known.

The test results that hot day in early August shouldn’t have surprised me — all the symptoms were there. A few days earlier, fatigue had enveloped me like a weighted blanket. I chalked it up to my weekend of travel. Next, a headache clamped down on the back of my skull.

20 Sep 2021

Medical staff with a history of allergy suffered adverse reactions to BNT162b2 COVID-19 vaccine

Scientists have addressed the gap in the research regarding the adverse reactions to the COVID-19 vaccine among individuals with allergies.

20 Sep 2021

Many cancer survivors continue to suffer long-term burdensome symptoms, study shows

Previous standards of cancer follow-up care and support may no longer meet current needs as improvements in screening practices, early diagnosis and treatment of cancer have put long-term survival beyond five years following diagnosis within reach for more than half of patients in Europe.

20 Sep 2021

Commonly prescribed cholesterol-lowering drugs could be effective in treating ulcerative colitis

There may be good news for the nearly 1 million people battling ulcerative colitis, a type of inflammatory bowel condition with no real cure: Statins, a commonly prescribed cholesterol-lowering drug, seem to be an effective, if unexpected, treatment for the condition, according to a new Stanford Medicine study.

20 Sep 2021

The influence of prior seasonal coronavirus infection on disease severity in COVID-19

A new study posted to the bioRxiv* server attempted to explore anti-spike IgG responses, Fc-gamma receptor (FcγR) activation, IgG targeting of immunodominant regions, and recall responses due to seasonal hCoV infections in non-hospitalized COVID-19 patients.

20 Sep 2021

AI can help with the diagnosis of B-cell lymphomas and related leukemias

The presence of cancer of the lymphatic system is often determined by analyzing samples from the blood or bone marrow.

18 Sep 2021

mAb treatment can rapidly select for SARS-CoV-2 resistance, suggests study

A study evaluates the efficacy of a mAb to prevent disease progression in non-hospitalized persons with symptomatic SARS-CoV-2 infection.

17 Sep 2021

Review: Long COVID symptoms rarely persisted beyond 12 weeks in young people

Long COVID symptoms rarely persisted beyond 12 weeks in children and adolescents, unlike adults. But more studies were required to investigate the risk and impact of long COVID in young people to help guide vaccine policy decisions in Australia, according to a review led by the Murdoch Children's Research Institute (MCRI).

17 Sep 2021

Pediatric SARS-CoV-2 infections usually mild, says study

A new study in the journal BMC Pediatrics describes the clinical phenotypes and outcomes in a thousand children who developed COVID-19.

16 Sep 2021

Novel combination therapy approach to keep leukemia at bay

In chronic leukemias, blocking the overactive kinase JAK2 by a targeted therapy approach is only mitigating the patients' symptoms, but cannot truly change the course of the disease.

16 Sep 2021

IL-1-Ra autoantibodies observed in high frequency in children with PIMS/MIS-C

Although severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection typically affects children only mildly, multisystem inflammatory syndrome in children (MIS-C) or pediatric inflammatory multisystem syndrome (PIMS) is a serious but rare complication occurring after infection.

16 Sep 2021

NYU Langone completes study designs for NIH research initiative on long-term impact of COVID-19

NYU Langone Health, as the Clinical Science Core for the National Institutes of Health's RECOVER initiative, has, since the announcement of the beginning of its operations on June 10, convened more than 100 researchers from 35 institutions as well as patients to finalize the main study protocols for the adult, pediatric, and autopsy patient groups (cohorts).

15 Sep 2021

NIH awards funding to build a national study population of volunteers on long-term effects of COVID-19

The National Institutes of Health awarded nearly $470 million to build a national study population of diverse research volunteers and support large-scale studies on the long-term effects of COVID-19.

15 Sep 2021

Analysis of the immune landscape in mild-to-moderate COVID-19

A new study includes an analysis of plasma cytokine levels, peripheral blood immune cell composition, and SARS-CoV-2 specific Igs in COVID-19.

15 Sep 2021

SARS-CoV-2 can cause sustained biochemical dysregulation that results in long-COVID

This state has come to be known as long-COVID, and in a paper recently uploaded to the preprint server medRxiv* by Simjanoska et al. (September 7th, 2021) the biochemical parameters of long-COVID patients with prior mild, moderate, or severe COVID-19 that resulted in hospitalization are tracked in detail, finding a characteristically dysregulated immune and inflammatory response in the most seriously ill.

15 Sep 2021

Fatigue News and Research

Researchers seek to identify the role of hypoxia on red blood cell aging

Nemours receives $10.5 million NIH grant to support research in sickle cell disease

Those undergoing treatment for hematological malignancies show reduced immune response to COVID-19 vaccines

New evidence confirms the efficacy of COVID-19 vaccination in cancer patients

Sunitinib extends progression-free survival in patients with rare neuroendocrine tumor, study shows

I got a ‘mild’ breakthrough case. Here’s what I wish I’d known.

Medical staff with a history of allergy suffered adverse reactions to BNT162b2 COVID-19 vaccine

Many cancer survivors continue to suffer long-term burdensome symptoms, study shows

Commonly prescribed cholesterol-lowering drugs could be effective in treating ulcerative colitis

The influence of prior seasonal coronavirus infection on disease severity in COVID-19

AI can help with the diagnosis of B-cell lymphomas and related leukemias

mAb treatment can rapidly select for SARS-CoV-2 resistance, suggests study

Review: Long COVID symptoms rarely persisted beyond 12 weeks in young people

Pediatric SARS-CoV-2 infections usually mild, says study

Novel combination therapy approach to keep leukemia at bay

IL-1-Ra autoantibodies observed in high frequency in children with PIMS/MIS-C

NYU Langone completes study designs for NIH research initiative on long-term impact of COVID-19

NIH awards funding to build a national study population of volunteers on long-term effects of COVID-19

Analysis of the immune landscape in mild-to-moderate COVID-19

SARS-CoV-2 can cause sustained biochemical dysregulation that results in long-COVID

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