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B cell accumulation triggers nervous system damage in MS

B cells are important in helping the immune system fight pathogens. However, in the case of the neurological autoimmune disease Multiple Sclerosis (MS) they can damage nerve tissue.

8 Nov 2018

Genetic inhibition of SARM1 prevents axonal degeneration in nervous systems

Disarm Therapeutics, a biotechnology company creating a new class of disease-modifying therapeutics for patients with axonal degeneration, a central driver of neurological disease, today announced data demonstrating that genetic inhibition of SARM1 prevents axonal degeneration in the central, ocular and peripheral nervous systems.

5 Nov 2018

Study reveals nature of how T cells protect the brain against harmful viruses

Researchers from the Netherlands Institute for Neuroscience and Amsterdam UMC have disclosed the nature of how T cells protect the brain against harmful viruses.

2 Nov 2018

New encyclopedia for adult and pediatric neuropsychological disorders

John DeLuca, PhD, a clinical neuropsychologist and Senior Vice President of Research and Training at Kessler Foundation, is the co-chief editor of the new 2nd edition "Encyclopedia of Clinical Neuropsychology". Published by Springer, it is the first major encyclopedia of adult and pediatric neuropsychological disorders.

2 Nov 2018

Repair defect in neurons hints at possible therapy for preventing ALS

Houston Methodist researchers have discovered a repair defect in nerve cells that send messages to the brain, opening the door to a possible therapy for preventing or slowing down ALS.

1 Nov 2018

Toxic protein assemblies found to play beneficial role in muscle generation

Toxic protein assemblies, or "amyloids," long considered to be key drivers in many neuromuscular diseases, also play a beneficial role in the development of healthy muscle tissue, University of Colorado Boulder researchers have found.

1 Nov 2018

Trump rollback of disability rules can make doctor’s visits painstaking

Going to the doctor's office can feel so routine. You sit in the waiting room, fill out the paperwork, get measured and hop onto the exam table.

31 Oct 2018

Genetic defect linked to ALS causes sugar-starved cells to overproduce lipids

A genetic defect tied to a variety of neurodegenerative diseases and mental illnesses changes how cells starved of sugar metabolize fatty compounds known as lipids, a new study led by researchers from the Johns Hopkins Bloomberg School of Public Health shows.

31 Oct 2018

UA pharmacology professors aim to avoid opioid analgesic tolerance

For thousands of Americans, opioids no longer relieve pain -- they cause pain. Known as "opioid tolerance," patients eventually become desensitized to opioids and more sensitive to pain after years of using the pain relievers.

31 Oct 2018

FDA approves ultra-high-field 7T Terra MRI scanner for clinical use

The ultra-high-field 7T Terra magnetic resonance imaging scanner at the USC Mark and Mary Stevens Neuroimaging and Informatics Institute of the Keck School of Medicine of USC has received FDA approval for clinical use, opening up new avenues of care for patients with Alzheimer's disease, multiple sclerosis and other diseases that affect the brain.

31 Oct 2018

Scientists pinpoint TIM-3 protein as next potential target for immunotherapy treatments

Following the 2018 Nobel Prize for Medicine, global attention is now more than ever turned toward the promise of immunotherapy in oncology. An international team’s work has shed new light on a molecule called TIM-3 that might play a key role in the regulation of the immune response.

31 Oct 2018

Individuals with integrated medical, behavioral, and pharmacy benefits are more engaged in their health, well-being

A study by global health service company Cigna Corporation (NYSE: CI) shows that individuals whose medical, behavioral and pharmacy health benefits are connected and administered by Cigna are more engaged in their health and well-being than those whose benefits are not fully integrated across medical, behavioral and pharmacy.

30 Oct 2018

UTHealth's Valentin Dragoi wins $1.6 million NIH award to unlock mysteries of the brain

Working to further the understanding of how the brain processes information, Valentin Dragoi, Ph.D., of The University of Texas Health Science Center at Houston has been awarded a three-year, $1.6 million award from the National Institutes of Health's Brain Research through Advancing Innovative Neurotechnologies Initiative.

30 Oct 2018

Study examines effects of walking exercise training on cognitive function in people with MS

John DeLuca, PhD, senior vice president for Research and Training at Kessler Foundation, has received a $95,000 sub-award from EMD Serono, the biopharmaceutical business of Merck KGaA, Darmstadt, Germany, in the U.S. and Canada.

29 Oct 2018

Biogen and Eisai present detailed results from phase 1b study of aducanumab at CTAD meeting

Biogen and Eisai Co., Ltd. announced that Biogen presented results at the Clinical Trials on Alzheimer's Disease meeting, in Barcelona, Spain, from the recent 36- and 48-month analyses of the ongoing long-term extension of the Phase 1b study of aducanumab, an investigational treatment for mild cognitive impairment due to Alzheimer's disease and mild AD.

29 Oct 2018

Stroke 'mimics' and 'chameleons' can complicate accurate diagnoses

Stroke specialists often see conditions known as stroke "mimics" and "chameleons" that can complicate accurate diagnoses, Loyola Medicine neurologists report in the November 2018 issue of Neuroimaging Clinics of North America.

26 Oct 2018

Scientists determine normal function of gene associated with ALS and FTD

The normal function of a gene associated with the neurodegenerative diseases amyotrophic lateral sclerosis and frontotemporal dementia has been determined for the first time by University of Bath scientists.

24 Oct 2018

Novartis: Lancet publishes pioneering study of Aimovig’s efficacy in episodic migraine patients

Novartis announced today that the full data from the LIBERTY study of Aimovig (erenumab) in episodic migraine patients who had tried and failed two to four prior preventive treatments have been published in the Lancet.

23 Oct 2018

Conceptual framework proposed to examine role of exercise in multiple sclerosis

Researchers have proposed a conceptual framework for examining the relationship between exercise and adaptive neuroplasticity in the population with multiple sclerosis (MS).

19 Oct 2018

Research points to new target for treating periodontitis

T cells help fight off infection, but they can go overboard. A new study led by researchers at the University of Pennsylvania School of Dental Medicine and the National Institutes of Health shows that a subset of T cells contributes to the problematic inflammation and bone loss that is associated with periodontitis, a severe form of gum disease.

17 Oct 2018