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Polymer nanoparticles for immunotherapy from encapsulated tumor-associated antigens and whole tumor cells

Using a biodegradable nanoparticle as a means of delivering tumor cell debris and proteins to the immune system, investigators at Yale University have developed a promising new method for creating therapeutic anticancer vaccines.

29 Jan 2007

SH2B1 protein plays a key role in controlling body weight, response to insulin and leptin

A single protein in brain cells may act as a linchpin in the body's weight-regulating system, playing a key role in the flurry of signals that govern fat storage, sugar use, energy balance and weight, University of Michigan Medical School researchers report.

29 Jan 2007

A plasminogen-activating protease specifically controls the development of primary pneumonic plague

The deadly attack of the bacterium that causes pneumonic plague is significantly slowed when it can't make use of a key protein, scientists at Washington University School of Medicine in St. Louis report in Science.

28 Jan 2007

Cellular mechanism linked to inflammation and cancer

A team led by biochemists at the University of California, San Diego has found what could be a long-elusive mechanism through which inflammation can promote cancer. The findings may provide a new approach for developing cancer therapies.

28 Jan 2007

RNA used to turn on genes to alleviate disease

A new technique that employs RNA, a tiny chemical cousin of DNA, to turn on genes could lead to therapeutics for conditions in which nudging a gene awake would help alleviate disease, researchers at UT Southwestern Medical Center say.

28 Jan 2007

Small molecule targets weak mRNA

A new strategy for fighting cancer aims to make its genes get lost in translation, according to a report in the January 26, 2007, issue of the journal Cell.

28 Jan 2007

Minor mistake in protein production at the cellular level may lead to serious neurological diseases

But exactly how the cell avoids such mistakes has remained unclear until now. Researchers at Ohio State University found the mechanism that prevents such errors, and explain their findings in the Proceedings of the National Academy of Sciences.

28 Jan 2007

Disorderly protein brings order to cell division

The secret to the ability of a molecule critical for cell division to throw off the protein yoke that restrains its activity is the yoke itself a disorderly molecule that seems to have a mind of its own, say investigators at St. Jude Children's Research Hospital, Innsbruck Medical University and Max Planck Institute.

28 Jan 2007

Using fibre in the fight against breast cancer

Wholemeal bread and wholegrain cereal could be key weapons in the battle against breast cancer.

24 Jan 2007

An active mind delays the onset of Alzheimer's

Learning appears to slow the development of two brain lesions that are the hallmarks of Alzheimer's disease, scientists at UC Irvine have discovered. The finding suggests that the elderly, by keeping their minds active, can help delay the onset of this degenerative disease.

23 Jan 2007

Single protein plays a major role in prion diseases

A single protein plays a major role in deadly prion diseases by smashing up clusters of these infectious proteins, creating the "seeds" that allow fatal brain illnesses to quickly spread, new Brown University research shows.

23 Jan 2007

Hepatitis C virus replication in transfected and serum-infected cultured human fetal hepatocytes

Researchers open the way for improved study of hepatitis C virus by devising a novel virus culture system that allows replication of patient-isolated virus in nontransformed hepatocytes, instead of culture-adapted virus strains in transformed cell lines.

23 Jan 2007

Scientists find surprising way of switching off a gene involved in cell division

Scientists at the University of Oxford have identified a surprising way of switching off a gene involved in cell division.

22 Jan 2007

Artificially engineered magnetic nanoparticles for ultra-sensitive molecular imaging

Iron oxide nanoparticles have shown promise as agents for detecting tumors using magnetic resonance imaging (MRI), but such efforts have been limited by the relatively weak magnetic signal generated by these nanoparticles.

22 Jan 2007

Dendrimer-based targeted delivery of an apoptotic sensor in cancer cells

Taking a critical step toward the development of a multifunctional nanoscale anticancer agent that can detect cancer, treat it, and then report on the success or failure of that treatment, investigators at the University of Michigan have developed a nanoscale sensor of cell death.

22 Jan 2007

Discovery of protein complex that plays important role in organ formation, cellular development and cicatrisation processes

Cellular movements are essential in organ formation processes, in cellular development and cicatrisation processes.

18 Jan 2007

G Protein News and Research

Polymer nanoparticles for immunotherapy from encapsulated tumor-associated antigens and whole tumor cells

SH2B1 protein plays a key role in controlling body weight, response to insulin and leptin

A plasminogen-activating protease specifically controls the development of primary pneumonic plague

Cellular mechanism linked to inflammation and cancer

RNA used to turn on genes to alleviate disease

Small molecule targets weak mRNA

Minor mistake in protein production at the cellular level may lead to serious neurological diseases

Disorderly protein brings order to cell division

Using fibre in the fight against breast cancer

An active mind delays the onset of Alzheimer's

Single protein plays a major role in prion diseases

Hepatitis C virus replication in transfected and serum-infected cultured human fetal hepatocytes

Scientists find surprising way of switching off a gene involved in cell division

Artificially engineered magnetic nanoparticles for ultra-sensitive molecular imaging

Dendrimer-based targeted delivery of an apoptotic sensor in cancer cells

Discovery of protein complex that plays important role in organ formation, cellular development and cicatrisation processes

Microfluidics gives boost to protein crystallization

Nanoparticles yield delivery tools for therapeutic nucleic acids

Targeting of cancer cells with ferrimagnetic ferritin cage nanoparticles

Biomimetic amplification of nanoparticle homing to tumors

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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