Protein C News and Research

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Researchers reveal potent new mechanism of action for treatment of IBD

Professor Akiyoshi Fukamizu's research group of Life Science Center for Survival Dynamics, University of Tsukuba, Eisai Co., Ltd. and its gastrointestinal business subsidiary EA Pharma Co., Ltd. have revealed a mechanism in which an analogue (ER-464195-01) of Eisai's in-house discovered E6007 inhibits integrin activation by dissociating interaction between calreticulin (CRT) and integrin α 4 (ITGA4), suppressing adhesion and infiltration of leukocytes overall.

25 May 2018

New findings could help fine-tune treatment for cancer patients

Cancer therapies that cut off blood supply to a tumor could be more effective in combination with existing chemotherapeutic drugs - according to new research from the University of East Anglia.

25 May 2018

Cancer cells co-opt pain-sensing 'neural channel' to increase tolerance against oxidative stress

Anyone who's taken a bite of a sandwich with too much spicy mustard or a piece of sushi with too much wasabi can attest to the tear-inducing sensation these condiments can cause. These loud warnings to the nervous system of exposure to potentially harmful chemicals are triggered by TRPA1, a calcium channel protein sometimes referred to as the "wasabi receptor."

25 May 2018

SLU researcher aims to find solutions for diabetes patients at risk of hypoglycemia

A $150,000 grant from The Leona M. and Harry B. Helmsley Charitable Trust will support research at Saint Louis University led by scientist Gina Yosten, Ph.D. Yosten's team is pursuing solutions for people with diabetes who are at risk of life-threatening drops in blood sugar known as hypoglycemia.

25 May 2018

Study reveals new protective mechanism for tumor cells in breast cancer

Greater knowledge of the mechanisms that contribute to the survival of tumor cells is key to vanquishing them.

25 May 2018

New drug-delivering nanoparticle could offer better way to treat brain tumors

Glioblastoma multiforme, a type of brain tumor, is one of the most difficult-to-treat cancers. Only a handful of drugs are approved to treat glioblastoma, and the median life expectancy for patients diagnosed with the disease is less than 15 months.

25 May 2018

FDA approves novel enzyme therapy for adults with rare and serious genetic disease

The U.S. Food and Drug Administration today approved Palynziq (pegvaliase-pqpz) for adults with a rare and serious genetic disease known as phenylketonuria (PKU).

25 May 2018

Researchers develop new, rapid blood test to detect liver damage

Chemist Vincent Rotello at the University of Massachusetts Amherst, with colleagues at University College London (UCL), U.K., announce today that they have developed a "quick and robust" blood test that can detect liver damage before symptoms appear, offering what they hope is a significant advance in early detection of liver disease. Details appear in Advanced Materials.

24 May 2018

Study defines molecular basis to explain connection between mother’s nutrition and infant growth

For years, pregnant mothers have questioned their nutritional habits: "Will eating more cause my baby to be overweight?" Or, "I'm eating for two, so it won't hurt to have an extra serving, right?"

24 May 2018

Researchers provide insight into how the memory molecule limits brain plasticity

The brain has an incredible capacity to support a lifetime of learning and memory. Each new experience fundamentally alters the connections between cells in the brain called synapses.

24 May 2018

Scientists uncover the cause of insulin resistance in obesity

A team of international researchers has identified a pathway by which obesity results in reduced insulin sensitivity.

24 May 2018

Couples who eat seafood-rich diet tend to get pregnant faster

Couples who eat more seafood tend to have sexual intercourse more often and get pregnant faster than other couples trying to conceive, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

24 May 2018

Tau mutations may serve as novel risk factor for cancer

Mutations to the protein tau, commonly associated with neurodegenerative disorders, may serve as a novel risk factor for cancer, according to results published in Cancer Research, a journal of the American Association for Cancer Research.

24 May 2018

Researchers take important step toward finding protein biomarkers during cancer surgery

Isabelle Fournier and her team are out to change surgical oncology. "Better surgery is associated with better prognosis and higher survival," said Fournier, a professor at the University of Lille and co-director of a proteomics center of INSERM, the French national institute of health.

24 May 2018

NIH commences first-in-human trial evaluating experimental treatment for Ebola

A first-in-human trial evaluating an experimental treatment for Ebola virus disease has begun at the National Institutes of Health (NIH) Clinical Center in Bethesda, Maryland.

24 May 2018

Whey protein supplementation and physical activity aid women in improving body composition

It's known that men benefit from whey protein supplements and exercise, and for what is believed to be the first time, the same can be said for women, according to a large study review by Purdue University nutrition experts.

23 May 2018

Skin cream containing rapamycin reduces TSC-related facial tumors

Addressing a critical issue for people with a genetic disorder called tuberous sclerosis complex, doctors at The University of Texas Health Science Center at Houston reported that a skin cream containing rapamycin significantly reduced the disfiguring facial tumors affecting more than 90 percent of people with the condition.

23 May 2018

Small part of cellular protein that helps form long-term memories also drives neurodegeneration

Scientists have just discovered that a small region of a cellular protein that helps long-term memories form also drives the neurodegeneration seen in Amyotrophic Lateral Sclerosis (ALS). This small part of the Ataxin-2 protein thus works for good and for bad.

23 May 2018

Study provides blueprint of how fruit flies can be used to screen potentially pathogenic human genes

It all began with one young patient; a 7-year old boy who was born without a thymus, an important organ of the immune system, and without functional immune cells. The boy also presented with cardiac and skeletal defects, dysmorphic craniofacial features and some signs of autistic behaviors.

23 May 2018

Comparative Analysis of a Complex Monoclonal Antibody

Postnova Analytics has published a new poster that compares the suitability of Electrical Asymmetrical Flow Field Flow Fractionation (EAF4) and Size Exclusion Chromatography (SEC) for determining the physicochemical and biophysical attributes of monoclonal antibodies.

From Postnova Analytics 23 May 2018

Protein C News and Research

Researchers reveal potent new mechanism of action for treatment of IBD

New findings could help fine-tune treatment for cancer patients

Cancer cells co-opt pain-sensing 'neural channel' to increase tolerance against oxidative stress

SLU researcher aims to find solutions for diabetes patients at risk of hypoglycemia

Study reveals new protective mechanism for tumor cells in breast cancer

New drug-delivering nanoparticle could offer better way to treat brain tumors

FDA approves novel enzyme therapy for adults with rare and serious genetic disease

Researchers develop new, rapid blood test to detect liver damage

Study defines molecular basis to explain connection between mother’s nutrition and infant growth

Researchers provide insight into how the memory molecule limits brain plasticity

Scientists uncover the cause of insulin resistance in obesity

Couples who eat seafood-rich diet tend to get pregnant faster

Tau mutations may serve as novel risk factor for cancer

Researchers take important step toward finding protein biomarkers during cancer surgery

NIH commences first-in-human trial evaluating experimental treatment for Ebola

Whey protein supplementation and physical activity aid women in improving body composition

Skin cream containing rapamycin reduces TSC-related facial tumors

Small part of cellular protein that helps form long-term memories also drives neurodegeneration

Study provides blueprint of how fruit flies can be used to screen potentially pathogenic human genes

Comparative Analysis of a Complex Monoclonal Antibody

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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