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Unmarried heart failure patients lack confidence to manage their condition, study says

Unmarried heart failure patients appear less confident in managing their condition and more socially limited compared to their married counterparts, according to research presented today at Heart Failure 2022, a scientific congress of the European Society of Cardiology.

22 May 2022

High air pollution may increase risk for life-threatening arrhythmias

Life-threatening arrhythmias are more common on days with highly polluted air, according to research presented today at Heart Failure 2022, a scientific congress of the European Society of Cardiology.

22 May 2022

Higher excess mortality found in Massachusetts during Omicron period than the Delta period

The COVID-19 pandemic has led to excess deaths - a higher number of fatalities than would be expected over a given period.

22 May 2022

Montefiore Einstein Cancer Center partners with the Price Family Foundation to advance cancer equity

The National Cancer Institute-designated Montefiore Einstein Cancer Center (MECC) has partnered with the Price Family Foundation to fund eight research teams developing novel cancer therapies and improving cancer outcomes for historically marginalized communities in the Bronx.

20 May 2022

Pioneering study could transform the treatment landscape for babies with infantile spasms

Infantile spasm (IS) is a severe epileptic syndrome of infancy and accounts for 50% of all epilepsy cases that occur in babies during the first year of life.

20 May 2022

New analysis finds increase in success and efficiency of chronic total occlusion percutaneous coronary intervention

A new analysis of PROGRESS-CTO (PROspective Global REgiStry for the Study of Chronic Total Occlusion Intervention; www.progresscto.org), an international multi-center registry of chronic total occlusion (CTO) percutaneous coronary intervention (PCI), was presented today as late-breaking clinical research at the Society for Cardiovascular Angiography & Interventions (SCAI) 2022 Scientific Sessions.

20 May 2022

Study finds no difference in survival between patients treated with paclitaxel drug-coated devices and non-DCDs

New long-term data from the Safety Assessment of Femoropopliteal Endovascular Treatment With PAclitaxel-coated Devices (SAFE-PAD) study were presented today as late-breaking clinical research at the Society for Cardiovascular Angiography & Interventions (SCAI) 2022 Scientific Sessions.

20 May 2022

APOB-specific T cells may contribute to inflammation and further the progression of atherosclerosis

Preventing atherosclerosis, the underlying cause of heart disease, means scientists need to understand how immune cells drive inflammation in the arteries.

20 May 2022

Discoveries may lead to new ways to treat patients with Allan-Herndon-Dudley syndrome

Two recent discoveries co-led by scientists at Cedars-Sinai may help lead to new ways to treat patients with Allan-Herndon-Dudley syndrome (AHDS), a brain development disorder that causes severe intellectual disability and problems with movement.

20 May 2022

Liver acuity circle allocation policy associated with procurement delays

A national policy change to facilitate the broader sharing of donor livers through "acuity circles" has resulted in procurement delays, according to a researcher at the University of Miami Miller School of Medicine.

20 May 2022

UNC-Chapel Hill secures $65 million NIH grant for establishing Antiviral Drug Discovery Center

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health awarded the UNC Gillings School of Global Public Health a $65 million grant establishing an Antiviral Drug Discovery Center to develop oral antivirals that can combat pandemic-level viruses like COVID-19.

20 May 2022

Molecular target discovery opens new pathways for developing effective anti-angiogenic cancer therapy

Researchers with The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute have identified a new molecular drug target that could result in new cancer drugs with fewer side effects.

20 May 2022

Novel brain-permeable Cdk5 inhibitor alters neurobehavior in mice

James Bibb, Ph.D., and colleagues have described a novel preclinical drug that could have the potential to combat depression, brain injury and diseases that impair cognition. The drug, which notably is brain-permeable, acts to inhibit the kinase enzyme Cdk5.

20 May 2022

Study outlines risk factors for autoimmune hepatitis after liver transplant

A multicenter study performed by a large international consortium that includes UT Southwestern has outlined a set of risk factors and outcomes for patients with autoimmune hepatitis (AIH) that recurs after liver transplantation.

20 May 2022

Blood-based biomarker can predict the benefit of immunotherapy to lung cancer patients

A blood-based tumor biomarker can predict the benefit of immunotherapy to patients with non-small cell lung cancer, according to a study published in Nature Medicine.

20 May 2022

Study demonstrates that ATV006 is orally bioavailable and has potent efficacy against SARS-CoV-2

A new study has revealed that ATV006, which is a 5′-hydroxyl-isobutyryl prodrug, possesses extraordinary oral pharmaco-kinetic (PK) profiles in rats and cynomolgus monkeys and exhibited significant antiviral activity against ancestral SARS-COV-2 strain as well as VOCs.

20 May 2022

Hyperinsulinemic patients with breast cancer may be responsive to metabolism-targeting treatments

Scientists at Yale Cancer Center have found that patients with breast cancer and high levels of insulin in the blood may be responsive to metabolism-targeting treatments, which in turn may improve the effectiveness of subsequent chemotherapy treatments.

20 May 2022

Multi-center trial shows promising results for implant-free interatrial shunt device to treat heart failure patients

Results from early clinical evaluation of the Alleviant System to treat heart failure patients with preserved and reduced ejection fraction (HFpEF and HFrEF) was presented today as late-breaking clinical research at the Society for Cardiovascular Angiography & Interventions (SCAI) 2022 Scientific Sessions.

20 May 2022

Clopidogrel monotherapy linked with reduced risk of net adverse clinical events, study finds

Results from a real-world study investigating safety and effectiveness of clopidogrel versus aspirin monotherapy beyond 12 months after PCI in high-risk patients during the chronic maintenance period.

20 May 2022

Household contact management could help avert 20% of the multi-drug resistant TB cases in children

One in five multi-drug resistant (MDR) tuberculosis (TB) cases in children under the age of 15 could be averted every year by household contact management, according to a new modeling study published in The Lancet Global Health.

20 May 2022

Medicine News and Research

Unmarried heart failure patients lack confidence to manage their condition, study says

High air pollution may increase risk for life-threatening arrhythmias

Higher excess mortality found in Massachusetts during Omicron period than the Delta period

Montefiore Einstein Cancer Center partners with the Price Family Foundation to advance cancer equity

Pioneering study could transform the treatment landscape for babies with infantile spasms

New analysis finds increase in success and efficiency of chronic total occlusion percutaneous coronary intervention

Study finds no difference in survival between patients treated with paclitaxel drug-coated devices and non-DCDs

APOB-specific T cells may contribute to inflammation and further the progression of atherosclerosis

Discoveries may lead to new ways to treat patients with Allan-Herndon-Dudley syndrome

Liver acuity circle allocation policy associated with procurement delays

UNC-Chapel Hill secures $65 million NIH grant for establishing Antiviral Drug Discovery Center

Molecular target discovery opens new pathways for developing effective anti-angiogenic cancer therapy

Novel brain-permeable Cdk5 inhibitor alters neurobehavior in mice

Study outlines risk factors for autoimmune hepatitis after liver transplant

Blood-based biomarker can predict the benefit of immunotherapy to lung cancer patients

Study demonstrates that ATV006 is orally bioavailable and has potent efficacy against SARS-CoV-2

Hyperinsulinemic patients with breast cancer may be responsive to metabolism-targeting treatments

Multi-center trial shows promising results for implant-free interatrial shunt device to treat heart failure patients

Clopidogrel monotherapy linked with reduced risk of net adverse clinical events, study finds

Household contact management could help avert 20% of the multi-drug resistant TB cases in children

Everything there is to know about biosimilars eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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