Efficacy News and Research

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Fluorescence device to diagnose atherosclerosis and tumors

In a presentation at the Conference on Lasers and Electro-Optics (CLEO), researchers from Cedars-Sinai Medical Center's Biophotonics Research and Technology Development Laboratory described recent progress on a device that stimulates, collects and measures light emissions from body tissues to diagnose critical atherosclerotic plaques (vulnerable plaques) and aggressive brain tumors.

29 May 2005

Taking the contraceptive pill may permanently supress womens libido

According to their research, a team at Boston University Medical College found that women who take the pill regularly have much lower levels of the hormone that drives sexual desire, and even more worrying, that hormone remains suppressed even when they come off the pill.

29 May 2005

Call for better monitoring of new devices after sudden death of college student

Thousands of people with diseased hearts who have undergone surgical implantation of a cardiac defibrillator, a mechanical device inserted under the skin that shocks a heart when it beats improperly, will be concerned after the death recently of a 21-year-old college student with a genetic heart abnormality who died of cardiac arrest while on a bicycle trip.

29 May 2005

Most serious side effects in statins may be higher in one of the newest drugs, rosuvastatin (Crestor)

A post-market analysis of cholesterol-lowering drugs called statins indicates that some of the most serious side effects may be higher in one of the newest drugs, rosuvastatin (Crestor). The drug is the strongest statin available because it has the greatest effect per milligram on low-density lipoprotein ("bad" cholesterol).

26 May 2005

Cyclophosphamide may be a possible therapy for scleroderma

A drug that suppresses the immune system and reduces inflammation has been shown to be effective in treating lung disease associated with the devastating connective tissue disease scleroderma, according to results presented at the American Thoracic Society International Conference on May 23.

24 May 2005

Risks outweigh benefits of shark cartilage as anti-cancer treatment

As a treatment for advanced cancer, shark cartilage fails to benefit patients and its adverse effects lead to poor compliance.

23 May 2005

Researchers generate patient-specific stem cells

Researchers have isolated the first human embryonic stem cell lines specifically tailored to match the nuclear DNA of patients, both males and females of various ages, suffering from disease or spinal cord injury.

20 May 2005

FDA recommends approval of the investigational anti-HIV drug tipranavir

Boehringer Ingelheim today announced that the U.S. Food and Drug Administration's (FDA) Antiviral Drugs Advisory Committee recommended the approval of the investigational anti-HIV drug tipranavir (11-3). Tipranavir is a non-peptidic protease inhibitor that requires boosting with low-dose ritonavir and must be used in combination with other antiretroviral agents.

20 May 2005

Integrated approach to child survival achieving important results

An integrated approach to child survival designed to deliver a package of lifesaving health services for children in hard to reach communities has shown remarkable results, UNICEF Executive Director Ann M. Veneman announced at the World Health Assembly.

18 May 2005

Roche to discontinue the sale and distribution of Fortovase (saquinavir)

Roche announced today that it has decided to discontinue the sale and distribution of Fortovase (saquinavir), as clinical demand for the drug has declined significantly due to the availability of a new formulation of Invirase (saquinavir mesylate), which increasingly has become the preferred formulation of saquinavir.

18 May 2005

More research needed into access to emergency contraception

Experts at The University of Nottingham have called for more research into whether systems for accessing emergency contraception are meeting the needs of younger women and those from poorer backgrounds.

17 May 2005

Antibody combined with cancer drug shows promise against breast tumors

An antibody that targets the blood vessels nourishing tumors significantly reduced breast cancer formation and growth in mice when combined with a current cancer drug, according to researchers at UT Southwestern Medical Center.

16 May 2005

Statin chemoprevention with minimal surveillance could prevent 96 percent of colon cancers

Ulcerative colitis affects about one out of every 2,000 Americans, and after living with the disease for 30 years, nearly 22 percent of those people will develop colon cancer.

16 May 2005

High-risk for melanoma patients no more likely to take proper precautions in the sun

Those considered high-risk for melanoma--the most dangerous form of skin cancer--are no more likely to sunbathe protected than those who are unaware of their risk, according to a new study conducted by McGill University Health Centre (MUHC) researchers.

16 May 2005

Emerging evidence supports early detection, monitoring, and in some cases treatment for children suffering from high blood pressure

One year after recommending that children should be checked for high blood pressure starting at age 3, medical experts reviewed additional supporting evidence for the pediatric blood pressure guidelines at the American Society of Hypertension's Twentieth Annual Meeting (ASH 2005).

16 May 2005

Tarvacin equivalent plus Docetaxel inhibits breast tumor growth by 93%

Peregrine Pharmaceuticals, Inc., today announced that a research article titled "A Monoclonal Antibody that Binds Anionic Phospholipids on Tumor Blood Vessels Enhances the Antitumor Effect of Docetaxel on Human Breast Tumors in Mice" was published in the May 15 issue of Cancer Research.

16 May 2005

Vaccine candidate to treat nicotine addiction shows promise

Cytos Biotechnology AG has announced that its vaccine candidate CYT002-NicQb to treat nicotine addiction has achieved proof of efficacy.

16 May 2005

Zometa reduces bone loss in patients receiving breast cancer treatment

Data presented at the American Society of Clinical Oncology (ASCO) annual meeting in Orlando, Florida, demonstrate that Zometa (zoledronic acid), an intravenous bisphosphonate, was shown to inhibit bone loss in postmenopausal women treated with Femara (letrozole) in the adjuvant breast cancer setting (directly following surgery to prevent cancer recurrence).

16 May 2005

Broader range of treatments for excessive sweating disorder, Mayo Clinic Proceedings says

The often embarrassing, excessive sweating disorder, hyperhidrosis, and its treatment options are gaining greater attention from physicians. This is improving the efficacy of treatment and minimizing its adverse effects, Mayo Clinic authors write in the May issue of Mayo Clinic Proceedings.

11 May 2005

Benitec announces clinical candidate for the treatment of Hepatitis C

Benitec Ltd. announced today that it has identified a highly promising clinical candidate for its RNA interference (RNAi)-based therapeutic against the hepatitis C virus (HCV).

10 May 2005