Efficacy News and Research

RSS

Glutathione found to significantly reduce acetaldehyde levels and help relieve hangovers

Study demonstrates that glutathione (GSH) significantly reduces acetaldehyde levels, a key factor in hangovers, though subjective symptoms showed little difference between groups. Pharmacokinetic data indicate that GSH accelerates acetaldehyde clearance, providing potential relief from hangover symptoms.

29 Sep 2024

Brusatol may serve as potential adjuvant therapy for pancreatic ductal adenocarcinoma

Announcing a new publication for Acta Materia Medica journal. Chemoresistance to gemcitabine (Gem) remains a substantial obstacle in the treatment of pancreatic ductal adenocarcinoma carcinoma (PDAC).

29 Sep 2024

Superabsorbent polymer beads linked to increasing cases of bowel obstruction in children

Water-absorbing beads have become increasingly hazardous to children over the past 10 years, as children who swallow the beads can experience life-threatening problems such as bowel obstruction.

27 Sep 2024

Estrogen found to promote tumor growth in breast cancers without receptors

Estrogens are known to drive tumor growth in breast cancer cells that carry its receptors, but a new study by Duke Cancer Institute researchers unexpectedly finds that estrogens play a role in fueling the growth of breast cancers without the receptors, as well as numerous other cancers.

27 Sep 2024

Novel approach combines glutaminase and HuR blockade to suppress breast cancer growth

A study led by Brazilian researchers and reported in an article published in the journal Nature Communications proposes that simultaneously targeting the enzyme glutaminase and the protein HuR, both of which are essential to tumor progression, may be effective in treating breast cancer.

27 Sep 2024

'Treating Naturally Occurring Disease’, explained by Founder, Professor Noel Fitzpatrick

Humanimal Trust advocates for studying naturally occurring diseases in animals to advance cancer and osteoarthritis treatments for both humans and animals.

27 Sep 2024

Study shows gradual waning of MMR vaccine effectiveness over time

The MMR vaccine remains the best protection against measles, according to a modelling study in England which suggests the level of protection decreases slightly over time.

27 Sep 2024

Digital games show promise for improving ADHD and depression in youth, but anxiety remains a challenge

A meta-analysis reveals gamified digital mental health interventions effectively reduce depression and ADHD in youth, highlighting engagement in treatment.

27 Sep 2024

TxGNN improves drug repurposing by predicting treatments for rare diseases with no approved therapies

A new model, TxGNN, revolutionizes zero-shot drug repurposing by predicting treatments for diseases with no known therapies, offering improved accuracy and trust via interpretable AI explanations.

27 Sep 2024

Perceived stress can directly trigger psoriasis relapse

Innovative research has provided compelling evidence that perceived stress can directly trigger the relapse of psoriatic skin lesions. The study, presented today at the European Academy of Dermatology and Venereology (EADV) Congress 2024, is the first to scientifically validate this connection in vivo.

26 Sep 2024

Purine metabolism disruptions highlighted as crucial in Parkinson’s disease development

Parkinson's disease (PD), the second most common neurodegenerative disorder globally, has long baffled scientists with its progressive nature and debilitating effects on motor function.

26 Sep 2024

Pilot trial aims to reduce rapid weight gain and obesity risk among Latine infants

With $784,369 from the NIH, UNCG researchers will implement a pilot trial that aims to reduce rapid weight gain and obesity risk among Latine infants by supporting mothers in breastfeeding.

26 Sep 2024

Innovative CAR-T cells effectively target glioblastoma with reduced toxicity

Glioblastoma is the most common and most aggressive primary brain tumor, with an average survival after diagnosis of less than two years, and against which current treatments remain ineffective.

26 Sep 2024

Brief behavioral intervention reduces intrusive memories of trauma in healthcare workers post-COVID-19

Researchers examine whether a cognitive task can reduce intrusive memories in healthcare workers exposed to traumatic experiences during the pandemic.

26 Sep 2024

Understanding the role of TIPS in improving renal function amid cirrhosis

Cirrhosis is one of the leading causes of mortality from non-communicable diseases, with complications arising as liver function deteriorates.

26 Sep 2024

Multi-omics analysis reveals mechanism of action for ruthenium-based anti-cancer agent

This study is led by Prof. Cai-Ping Tan, Prof. Zong-Wan Mao (MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University) and Prof. Zheng-Qiu Li (School of Pharmacy, MOE Key Laboratory of Tumor Molecular Biology, Jinan University).

26 Sep 2024

Drug-free nasal spray demonstrates effectiveness in blocking viral and bacterial infections

Researchers from the Brigham detail how the spray they created may offer broad-spectrum protection from respiratory infections by COVID-19, influenza, everyday cold viruses, and pneumonia-causing bacteria

25 Sep 2024

New pipeline of drug candidates offers hope for effective MASLD treatments

Non-alcoholic fatty liver disease (NAFLD), recently reclassified as metabolic dysfunction-associated steatotic liver disease (MASLD), has become the most prevalent chronic liver disease globally.

25 Sep 2024

Higher doses of buprenorphine linked to lower emergency visits in opioid use disorder

Adults with opioid use disorder who receive a higher daily dose of the opioid addiction treatment medication buprenorphine may have a lower risk of subsequent emergency department visits or use of inpatient services related to behavioral health (such as for mental health and substance use disorders) than adults receiving the recommended dose, according to an analysis funded by the National Institutes of Health (NIH).

25 Sep 2024

Steritas' Pediatric Glucocorticoid Toxicity Index applied in clinical trial to assess steroid-toxicity

Steritas LLC., a company dedicated to enhancing patient care for steroid-treated patients announced that Alder Hey Children’s NHS Foundation Trust, and the Liverpool Clinical Trials Centre will apply its Steritas Pediatric Glucocorticoid Toxicity Index (pGTI) in a clinical trial to compare efficacy, safety and cost-effectiveness of intravenous versus oral glucocorticoids (steroids) for children and young people with Juvenile Idiopathic Arthritis (JIA).

From Steritas LLC 25 Sep 2024

Efficacy News and Research

Glutathione found to significantly reduce acetaldehyde levels and help relieve hangovers

Brusatol may serve as potential adjuvant therapy for pancreatic ductal adenocarcinoma

Superabsorbent polymer beads linked to increasing cases of bowel obstruction in children

Estrogen found to promote tumor growth in breast cancers without receptors

Novel approach combines glutaminase and HuR blockade to suppress breast cancer growth

'Treating Naturally Occurring Disease’, explained by Founder, Professor Noel Fitzpatrick

Study shows gradual waning of MMR vaccine effectiveness over time

Digital games show promise for improving ADHD and depression in youth, but anxiety remains a challenge

TxGNN improves drug repurposing by predicting treatments for rare diseases with no approved therapies

Perceived stress can directly trigger psoriasis relapse

Purine metabolism disruptions highlighted as crucial in Parkinson’s disease development

Pilot trial aims to reduce rapid weight gain and obesity risk among Latine infants

Innovative CAR-T cells effectively target glioblastoma with reduced toxicity

Brief behavioral intervention reduces intrusive memories of trauma in healthcare workers post-COVID-19

Understanding the role of TIPS in improving renal function amid cirrhosis

Multi-omics analysis reveals mechanism of action for ruthenium-based anti-cancer agent

Drug-free nasal spray demonstrates effectiveness in blocking viral and bacterial infections

New pipeline of drug candidates offers hope for effective MASLD treatments

Higher doses of buprenorphine linked to lower emergency visits in opioid use disorder

Steritas' Pediatric Glucocorticoid Toxicity Index applied in clinical trial to assess steroid-toxicity

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News