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Genomes of marine invertebrates found to be surprisingly stable across deep time

Scientists have discovered that the genomes of marine invertebrates have been surprisingly stable across deep time.

6 Feb 2022

Gene therapy helps heart muscle cells electrically activate in live mice

Biomedical engineers at Duke University have demonstrated a gene therapy that helps heart muscle cells electrically activate in live mice.

4 Feb 2022

Memory B cells found to potently neutralize SARS-CoV-2 Omicron variant

A team of researchers recently captured memory B cells from a cohort of SARS-CoV-2 convalescent or mRNA-vaccinated individuals to study the evolution of B cell-mediated antibody responses to the N-terminal domain in humans.

4 Feb 2022

Molecular simulations provide insight into SARS-CoV-2 variant RBD interactions with ACE2 and mAbs

Researchers aimed to understand the relationship between the SARS-CoV-2 receptor-binding domain and both human receptors and therapeutic targets.

3 Feb 2022

Evaluating effects of D614G and P681R/H mutations on SARS-CoV-2 VOCs

Researchers evaluate how the D614G and P681H mutations alter the attributes of SARS-CoV-2 VOCs.

3 Feb 2022

Global efforts to track COVID-19 variants grossly underreported a probable variant of concern in Nigeria

If the United States ignores COVID-19 in Nigeria, we forgo global genomic surveillance at our own peril, reports a new Northwestern Medicine study published in Nature Communications.

3 Feb 2022

New method may be effective at quantifying DNA adenine methylation in complex organisms

For decades, a small group of cutting-edge medical researchers have been studying a biochemical, DNA tagging system, which switches genes on or off. Many have studied it in bacteria and now some have seen signs of it in, plants, flies, and even human brain tumors.

3 Feb 2022

Genome study reveals unexpected heterogeneity of human ribosomal RNA genes

A genome study undertaken by Johns Hopkins Kimmel Cancer Center researchers to look for variants in a gene considered a fundamental building block for microscopic structures that synthesize proteins took a surprising twist.

2 Feb 2022

N gene target failure method effectively detects SARS-CoV-2 Omicron in clinical samples

In a new study, researchers demonstrated that a commercial real-time polymerase chain reaction (RT-PCR) assay rapidly detects the SARS-CoV-2 Omicron variant.

2 Feb 2022

Study proposes Omicron variant may be derived from recombination of two early SARS-CoV-2 PANGO lineages

A recent study showed that the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) Omicron variant is a chimera of two earlier PANGO lineages of SARS-CoV-2.

2 Feb 2022

Illustrating the structural diversity of SARS-CoV-2 Omicron spike

In a new study, a team of researchers used cryo-electron microscopy to determine the spike (S) structures of the SARS-CoV-2 Omicron variant to understand how the mutations that alter its primary sequence impact S conformation.

1 Feb 2022

New study on mutation origination fundamentally challenges neo-Darwinism

A new study by a team of researchers from Israel and Ghana has brought the first evidence of nonrandom mutation in human genes, challenging a core assumption at the heart of evolutionary theory by showing a long-term directional mutational response to environmental pressure.

31 Jan 2022

How many lives would vaccine sharing have saved?

In a new study, researchers have been investigating different COVID-19 vaccine sharing simulations, and how they would affect affect global mortality.

31 Jan 2022

COVID-19 vaccines elicit cross-reactive antibodies against endemic coronaviruses

Researchers study the interaction between immunity to endemic coronaviruses and SARS-CoV-2.

30 Jan 2022

Damon Runyon Cancer Research Foundation announces newest cohort of Fellows and Breakthrough Scientists

The Damon Runyon Cancer Research Foundation has announced its newest cohort of Damon Runyon Fellows, 13 outstanding postdoctoral scientists conducting basic and translational cancer research in the laboratories of leading senior investigators.

29 Jan 2022

Study reveals potential new way to treat breast cancer brain metastases

A study led by researchers at RCSI University of Medicine and Health Sciences and the Beaumont RCSI Cancer Centre (BRCC) has revealed a potential new way to treat secondary breast cancer that has spread to the brain, using existing drugs.

28 Jan 2022

A synthesis of evidence sheds light on major immune components and mechanisms involved in COVID-19

New research highlights principal host factors that may explain the immune responses to SARS-CoV-2 and its variants in the context of infection susceptibility, disease severity, and previous immunity.

28 Jan 2022

Exploring receptor-blocking conserved non-neutralizing antibodies for SARS-CoV-2 therapy

In a new study, researchers hypothesized and developed broad-spectrum SARS-CoV-2 inhibitors, ReconnAbs, by modifying the existing non-neutralizing antibodies targeted towards the highly conserved epitopes of the SARS-CoV-2 spike (S) protein combined with a receptor-blocking component.

28 Jan 2022

ERGA aims to provide genomic data to inform research about Europe's biodiversity

To provide important genomic data to inform research about Europe's biodiversity, scientists from 48 different countries initiated the "European Reference Genome Atlas" (ERGA) in 2021.

28 Jan 2022

SARS-CoV-2 virus may be shed for much longer periods by some infected patients, study shows

In a 38-year-old man who manifested mild symptoms of COVID-19 for 20 days, the novel coronavirus continued to be detected in his organism and to undergo mutations for 232 days.

27 Jan 2022

Evolution News and Research

Genomes of marine invertebrates found to be surprisingly stable across deep time

Gene therapy helps heart muscle cells electrically activate in live mice

Memory B cells found to potently neutralize SARS-CoV-2 Omicron variant

Molecular simulations provide insight into SARS-CoV-2 variant RBD interactions with ACE2 and mAbs

Evaluating effects of D614G and P681R/H mutations on SARS-CoV-2 VOCs

Global efforts to track COVID-19 variants grossly underreported a probable variant of concern in Nigeria

New method may be effective at quantifying DNA adenine methylation in complex organisms

Genome study reveals unexpected heterogeneity of human ribosomal RNA genes

N gene target failure method effectively detects SARS-CoV-2 Omicron in clinical samples

Study proposes Omicron variant may be derived from recombination of two early SARS-CoV-2 PANGO lineages

Illustrating the structural diversity of SARS-CoV-2 Omicron spike

New study on mutation origination fundamentally challenges neo-Darwinism

How many lives would vaccine sharing have saved?

COVID-19 vaccines elicit cross-reactive antibodies against endemic coronaviruses

Damon Runyon Cancer Research Foundation announces newest cohort of Fellows and Breakthrough Scientists

Study reveals potential new way to treat breast cancer brain metastases

A synthesis of evidence sheds light on major immune components and mechanisms involved in COVID-19

Exploring receptor-blocking conserved non-neutralizing antibodies for SARS-CoV-2 therapy

ERGA aims to provide genomic data to inform research about Europe's biodiversity

SARS-CoV-2 virus may be shed for much longer periods by some infected patients, study shows

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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