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Specific immune cells may help slow progression of ALS, research shows

New research into Amyotrophic Lateral Sclerosis (ALS) - also known as motor neuron disease - shows that specific immune cells may help slow progression of the disease, an important step towards developing new therapies to treat patients.

22 Mar 2018

Immune cells can repopulate in the retina after elimination, mice study shows

Immune cells called microglia can completely repopulate themselves in the retina after being nearly eliminated, according to a new study in mice from scientists at the National Eye Institute.

21 Mar 2018

Researchers explain link between 2 key Alzheimer's proteins

It's a paradox of Alzheimer's disease: Plaques of the sticky protein amyloid beta are the most characteristic sign in the brain of the deadly neurodegenerative disease. However, many older people have such plaques in their brains but do not have dementia.

21 Mar 2018

Neuroscientists move closer to developing tools for deciphering brain function

A team of University of Missouri neuroscientists are inching closer to developing the tools needed to decipher the brain.

21 Mar 2018

Discovery of new ALS gene points to cytoskeleton as potential target for drug development

An international team of researchers led by John Landers, PhD, at UMass Medical School, and Bryan Traynor, MD, PhD, at the National Institute on Aging at the National Institutes of Health, has identified KIF5A as a new gene associated with the development of amyotrophic lateral sclerosis.

21 Mar 2018

Fearful worms provide new clues about human anxiety

Ask a dozen people about their greatest fears, and you'll likely get a dozen different responses. That, along with the complexity of the human brain, makes fear--and its close cousin, anxiety--difficult to study.

19 Mar 2018

Scientists discover basic molecular mechanism that helps understand how ALS works

It took eight long years of research, but now an international team led by neuroscientists at Université de Montréal has discovered a basic molecular mechanism that better helps understand how Lou Gehrig's disease, or amyotrophic lateral sclerosis (ALS), works.

19 Mar 2018

Neuroscientists identify role of primary visual cortex in integrating head and visual movement signals

Neuroscientists at the Sainsbury Wellcome Centre have identified a circuit in the primary visual cortex (V1) of the brain that integrates head- and visual-motion signals.

15 Mar 2018

Songbirds provide insight into how specific neurons may guide vocal learning in humans

Songbirds are providing insight into how a specific set of neurons may guide the learning of vocal behaviors in humans.

15 Mar 2018

Transplanting enhanced interneurons restores brain rhythms in mouse model of Alzheimer’s

Like a great orchestra, your brain relies on the perfect coordination of many elements to function properly. And if one of those elements is out of sync, it affects the entire ensemble. In Alzheimer's disease, for instance, damage to specific neurons can alter brainwave rhythms and cause a loss of cognitive functions.

15 Mar 2018

Study reveals mechanisms underlying maintenance of memory during sleep hours

During the hours of sleep the memory performs a cleaning shift. A study led by a Spanish scientist at the University of Cambridge reveals that when we sleep, the neural connections that collect important information are strengthened and those created from irrelevant data are weakened until they get lost.

15 Mar 2018

OIST scientists model molecular basis of learning in the cerebellum

The process we call learning is in fact a well-orchestrated symphony of thousands of molecular reactions, but the exact interplay between these reactions remains largely unknown.

15 Mar 2018

Researchers uncover link between Parkinson’s disease mutations and plaque formation in the brain

Working with lab-grown human brain cells, Johns Hopkins researchers report they have uncovered a much sought-after connection between one of the most common genetic mutations in Parkinson's disease and the formation of fatty plaques in the brain thought to contribute to the destruction of motor neurons that characterize the disease.

15 Mar 2018

Researchers identify B immune cells that promote axon myelination in developing neurons

Neurons are specialized cells of the nervous system that communicate using electrical signals, which propagate down long, wire-like projections called axons. The conduction of these signals requires myelin, a fatty substance that surrounds axons in much the same way that plastic coating surrounds an electrical wire.

13 Mar 2018

NIH-funded researchers use CRISPR to rapidly find new genetic suspects behind ALS, FTD

NIH-funded researchers at Stanford University used the gene editing tool CRISPR-Cas9 to rapidly identify genes in the human genome that might modify the severity of amyotrophic lateral sclerosis and frontotemporal dementia caused by mutations in a gene called C9orf72.

13 Mar 2018

Impaired transport processes in neurons contribute to neurodegenerative disorders

Two partners have to find their way to each other in order to transport substances to the remote ends of special nerve fibers to maintain their function. If this partnering process is disturbed, the cells may die in the worst case, resulting in neurodegenerative disorders such as amyotrophic lateral sclerosis (ALS) or spinal muscular atrophy.

9 Mar 2018

Your stress can rub off on others

In a recent study, scientists found that when exposed to another individual’s stress, the brain reacts as it does to real stress.

9 Mar 2018

Scientists uncover detailed map of the brain circuits behind thirst and satiety

Scientists uncovered a high-resolution map of the wiring inside the mouse brain's thirst center. With these blueprints, they could trick mice into becoming light or heavy water drinkers.

8 Mar 2018

Boosting the brain's immune cells may prevent or reduce severity of Alzheimer's disease

Sanford Burnham Prebys Medical Research Institute researchers have published two new studies in Neuron that describe how TREM2, a receptor found on immune cells in the brain, interacts with toxic amyloid beta proteins to restore neurological function.

8 Mar 2018

High-resolution fMRI provides clues about age-related memory differences

As we get older, it's not uncommon to experience "senior moments," in which we forget where we parked our car or call our children by the wrong names. And we may wonder: Are these memory lapses a normal part of aging, or do they signal the early stages of a severe disorder such as Alzheimer's disease? Currently, there's no good way to tell.

8 Mar 2018

Neuron News and Research

Specific immune cells may help slow progression of ALS, research shows

Immune cells can repopulate in the retina after elimination, mice study shows

Researchers explain link between 2 key Alzheimer's proteins

Neuroscientists move closer to developing tools for deciphering brain function

Discovery of new ALS gene points to cytoskeleton as potential target for drug development

Fearful worms provide new clues about human anxiety

Scientists discover basic molecular mechanism that helps understand how ALS works

Neuroscientists identify role of primary visual cortex in integrating head and visual movement signals

Songbirds provide insight into how specific neurons may guide vocal learning in humans

Transplanting enhanced interneurons restores brain rhythms in mouse model of Alzheimer’s

Study reveals mechanisms underlying maintenance of memory during sleep hours

OIST scientists model molecular basis of learning in the cerebellum

Researchers uncover link between Parkinson’s disease mutations and plaque formation in the brain

Researchers identify B immune cells that promote axon myelination in developing neurons

NIH-funded researchers use CRISPR to rapidly find new genetic suspects behind ALS, FTD

Impaired transport processes in neurons contribute to neurodegenerative disorders

Your stress can rub off on others

Scientists uncover detailed map of the brain circuits behind thirst and satiety

Boosting the brain's immune cells may prevent or reduce severity of Alzheimer's disease

High-resolution fMRI provides clues about age-related memory differences

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