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New treatments for common vaginal infection being studied

Whether a two-week regimen using a stainless steel douching device can eradicate the most common vaginal infection is under study at the Medical College of Georgia.

9 May 2005

Does clinical depression bring about chronic pain? Or does pain lead to depression?

Does clinical depression bring about chronic pain? Or does pain lead to depression? Because these two conditions frequently co-exist--30 to 54 percent of patients with major depressive disorder also suffer persistent physical pain--there has been much speculation about whether one causes the other or whether a common underlying factor provokes both. Results of studies into the precise nature of this relationship, however, have been inconsistent.

5 May 2005

Fear stops some parents vaccinating their children

A new study has found that the majority of parents who choose not to vaccinate their children do so out of fear that the vaccine will cause more harm than the disease it prevents.

4 May 2005

Vaccine developed at Rockefeller University boosts natural killer T cells in patients with cancer

A new vaccine designed at The Rockefeller University boosted a type of fast-responding immune system cell called the natural killer T (NKT) cell in patients with advanced cancer. The study surprised researchers by revealing the ability of these NKT cells to spur other, slower-responding immune cells to go to work.

4 May 2005

New Zealand Ministry of Health to consider Vaxigrip vaccine trial results

Pharmac and the New Zealand Ministry of Health are aware that Sanofi-Pasteur has been running a clinical trial to demonstrate the efficacy of their influenza vaccine, Vaxigrip.

4 May 2005

Boostrix receives FDA approval as treatment for pertussis

GlaxoSmithKline today announced that its booster vaccine, Boostrix received approval from the United States (U.S.) Food and Drug Administration (FDA).

3 May 2005

Study identifies possible marker for efficacy of gefitinib in lung cancer patients

Patients with advanced non–small-cell lung cancer (NSCLC) whose tumor cells contain extra copies of the epidermal growth factor receptor (EGFR) gene may be more likely to respond to the drug gefitinib (Iressa), and this high gene copy number may be an effective predictor of gefitinib efficacy, according to a new study in the May 4 issue of the Journal of the National Cancer Institute.

3 May 2005

Coronary artery stents that release medication appear more effective than traditional stents for patients with heart attack

A type of coronary artery stent that releases a medication appears to result in better outcomes than traditional stents for heart attack patients, according to a study in the May 4 issue of JAMA.

3 May 2005

Long-term outcomes promising for patients with localized, low-grade prostate cancer

A study that includes 20 years of follow-up does not support aggressive treatment for localized, low-grade prostate cancer, with data indicating a small risk of progression of this grade of cancer, according to a study in the May 4 issue of JAMA.

3 May 2005

Milk thistle not proven effective in lowering mortality in alcoholic or hepatitis B or C liver disease

While some studies found that liver-related mortality may be significantly reduced in patients treated with milk thistle, these findings were not duplicated in the higher quality clinical trials.

2 May 2005

Promising results from study of Pirfenidone in idiopathic pulmonary fibrosis (IPF) patients

InterMune today announced that the American Journal of Respiratory and Critical Care Medicine (AJRCCM) published results from a double-blind, randomized, placebo-controlled Phase II trial evaluating pirfenidone for the treatment of patients with idiopathic pulmonary fibrosis (IPF).

2 May 2005

Giving children access to drug clinical trials is crucial, clofarabine approval shows

The accelerated approval of the drug clofarabine to treat relapsed or refractory pediatric acute lymphoblastic leukemia (ALL) demonstrates the importance of offering children rapid access to new treatments through clinical trials, according to investigators at St. Jude Children's Research Hospital. Refractory or relapsed ALL is a disease that resists treatment.

2 May 2005

Solar cell implant may restore some sight for the blind

Ophthalmologists at Rush University Medical Center implanted Artificial Silicon Retina (ASR) microchips in the eyes of five patients to treat vision loss caused by retinitis pigmentosa (RP). The implant is a silicon microchip 2mm in diameter and one-thousandth of an inch thick, less than the thickness of a human hair.

1 May 2005

Antibiotic minocycline might help alleviate HIV's negative effects on the brain and central nervous system

By studying animals, Johns Hopkins researchers have discovered that the antibiotic minocycline might help alleviate HIV's negative effects on the brain and central nervous system, problems that can develop even though antiretroviral therapy controls the virus elsewhere in the body.

1 May 2005

Ginkgo beneficial for multiple sclerosis symptoms

When it comes to her health, Janice Winfield of Portland, Ore., does her research. That's why the stay-at-home mom, who was diagnosed with multiple sclerosis in July 2000, was willing to turn to popular, over-the-counter herbal supplements like ginkgo biloba to deal with memory problems, fatigue and occasional muscle pain.

27 Apr 2005

Patients' lives at risk from substandard drugs say heart specialists

Global action is needed to counter the dangers of substandard life-saving drugs that are putting patients' lives and health at risk, according to heart specialists writing in the new (19 April) issue of Europe's leading cardiology journal, the European Heart Journal.

27 Apr 2005

Drug adverts are a haphazard approach to health promotion

As California State Assembly Bill 95 (Koretz, D-West Hollywood), designed to reign in drug marketing costs in California by requiring manufacturers of drugs for life-threatening chronic conditions to pay the state a rebate equal to the drug marketing cost, moves to the Assembly Appropriations Committee, AIDS Healthcare Foundation (AHF) -- cites a study and accompanying editorial published today in the Journal of American Medical Association (JAMA) that demonstrates the influence that Direct to Consumer Advertising (DTCA) has on physicians' prescribing decisions.

26 Apr 2005

Gene therapy for Alzheimer's disease shows promise

In the first clinical trial of gene therapy for Alzheimer's disease researchers have produced preliminary evidence that gene therapy may slow the decline in mental functioning associated with Alzheimer's disease.

25 Apr 2005

Molecular models advance the fight against malaria

Research from Dartmouth Medical School, demonstrating how malaria parasites form mutations that make them stubbornly resistant to drug therapy, may hold the key to a new treatments for a disease that afflicts more than half a billion people worldwide.

25 Apr 2005

How Ebola virus infects cells - discovery

Ebola virus reproduction in laboratory-grown cells is severely hampered by enzyme-inhibiting chemicals, and these chemicals deserve further study as possible treatments for Ebola virus infections in humans, report scientists supported in part by the National Institute of Allergy and Infectious Diseases (NIAID).

23 Apr 2005

Efficacy News and Research

New treatments for common vaginal infection being studied

Does clinical depression bring about chronic pain? Or does pain lead to depression?

Fear stops some parents vaccinating their children

Vaccine developed at Rockefeller University boosts natural killer T cells in patients with cancer

New Zealand Ministry of Health to consider Vaxigrip vaccine trial results

Boostrix receives FDA approval as treatment for pertussis

Study identifies possible marker for efficacy of gefitinib in lung cancer patients

Coronary artery stents that release medication appear more effective than traditional stents for patients with heart attack

Long-term outcomes promising for patients with localized, low-grade prostate cancer

Milk thistle not proven effective in lowering mortality in alcoholic or hepatitis B or C liver disease

Promising results from study of Pirfenidone in idiopathic pulmonary fibrosis (IPF) patients

Giving children access to drug clinical trials is crucial, clofarabine approval shows

Solar cell implant may restore some sight for the blind

Antibiotic minocycline might help alleviate HIV's negative effects on the brain and central nervous system

Ginkgo beneficial for multiple sclerosis symptoms

Patients' lives at risk from substandard drugs say heart specialists

Drug adverts are a haphazard approach to health promotion

Gene therapy for Alzheimer's disease shows promise

Molecular models advance the fight against malaria

How Ebola virus infects cells - discovery

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