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Molecular chaperones protect cells

Falsely folded proteins and their aggregations in neurons are considered to be the cause of neurodegenerative diseases, among them Chorea Huntington.

13 Sep 2006

High copayments for 'specialty pharmacy' medications has little effect on use

Higher copayments have a small effect on usage of "specialty pharmacy" medications, which can cost as much as $10,000 monthly, according to a study published Tuesday in the journal Health Affairs, the Pittsburgh Post-Gazette reports.

13 Sep 2006

First step to developing effective therapy against Venezuelan Equine Encephalitis virus

Biomedical researchers at the University of Texas Medical Branch at Galveston (UTMB) have taken an important early step toward developing effective drug therapies against Venezuelan Equine Encephalitis (VEE) virus, a potential bioterrorist weapon.

12 Sep 2006

Brown seaweed with anti-obesity potential!

Scientists believe they may have found something to combat obesity and it may also help prevent the onset of diabetes.

12 Sep 2006

High levels of two proteins in the bloodstream indicate need for action to avoid heart attack

Researchers working to decode chemical SOS signals sent out by disease-damaged hearts believe they now know better when to aggressively clear clogged arteries and when medical procedures may be unnecessary and even harmful.

12 Sep 2006

GRK2 protein -a potential biomarket for heart failure

A team of cardiology researchers at Thomas Jefferson University has determined that GRK2, a protein that plays an important regulatory role in heart failure, is elevated in patients with failing hearts when compared to patients with normal heart function.

12 Sep 2006

Drug infliximab may help ease ulcerative colitis

In good news for patients with stubborn cases of ulcerative colitis, a serious intestinal disorder, a new research review suggests that the drug infliximab can be a useful alternative if other treatments don't work.

12 Sep 2006

Nanocantilevers as future disease detectors

Researchers at Purdue University have made a discovery about the behavior of tiny structures called nanocantilevers that could be crucial in designing a new class of ultra-small sensors for detecting viruses, bacteria, and other pathogens.

12 Sep 2006

Synthetic low-density lipoprotein-like nanoparticles target brain tumors

Low-density lipoprotein, better known as LDL, is one of the chief villains involved in the development of coronary artery disease.

12 Sep 2006

Study shows how the plague bacteria Yersinia pestis causes disease

The bacteria responsible for the plague and some forms of food poisoning "paralyze" the immune system of their hosts in an unexpected way, according to a new study in the September 8, 2006 issue of the journal Cell.

7 Sep 2006

HIV needs human protein - potential therapy target

Mayo Clinic virologists have discovered that a specific human protein is essential for HIV to integrate into the human genome.

7 Sep 2006

NIH launches "Knockout Mouse Project"

The National Institutes of Health (NIH) today awarded a set of cooperative agreements, totaling up to $52 million over five years, to launch the Knockout Mouse Project.

7 Sep 2006

Genetic code for breast and colon cancers

Johns Hopkins Kimmel Cancer Center scientists have completed the first draft of the genetic code for breast and colon cancers.

7 Sep 2006

New avenue for the pursuit of therapies for Alzheimer's disease

The genes responsible for an inherited form of Alzheimer's disease play a direct role within cells that has largely been overlooked, according to a report in the September 8, 2006 issue of the journal Cell.

7 Sep 2006

Protein test on lung cancer cells predicts who will benefit from chemo

European researchers say a test can predict whether chemotherapy will help patients with lung cancer live longer after surgery.

7 Sep 2006

Closing in on lethal arrhythmogenic right ventricular dysplasia in young athletes

Johns Hopkins experts on the genetics of a potentially lethal heart rhythm defect that runs in families and targets young athletes report they have greatly narrowed the hunt for the specific genetic mutations that contribute to the problem.

7 Sep 2006

FDA releases draft guidelines regulating complex diagnostic tests

FDA on Tuesday released draft guidelines that assert the agency's authority for regulating gene- and protein-based diagnostic tests for conditions such as breast cancer and ovarian cancer, the Wall Street Journal reports.

6 Sep 2006

Children with lactose intolerance still need dairy's nutrients

The American Academy of Pediatrics (AAP) is recommending in a new report that children with lactose intolerance should include dairy foods as part of a healthy diet in order to get enough calcium, vitamin D, protein and other nutrients essential for bone health and overall growth.

6 Sep 2006

Quantum dot nanodevice that can detect and image apoptosis

Aiming to help researchers get a better handle on how - and if - anticancer agents are triggering cell death, investigators at the University of Twente in The Netherlands have developed a quantum dot nanodevice that can detect and image apoptosis, also known as programmed cell death.

5 Sep 2006

New method for attaching tumor-targeting antibodies to the surface of buckyballs

Hollow buckyballs, spherical molecules made of sixty carbon atoms linked to one another like the panels of a soccer ball, have the potential to ferry large doses of anticancer drugs or imaging agents to tumors.

5 Sep 2006