Efficacy News and Research

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Biotoxin from puffer fish may provide treatment for opioid withdrawal

On November 10, 2004 investigators involved in a Phase IIa clinical trial of the novel biotoxin Tetrodotoxin (TTX) for the treatment of opioid withdrawal enrolled their first participants.

18 Nov 2004

Low-cost antibiotic co-trimoxazole should be given to all children with HIV in developing countries

Results of a randomised trial in this week’s issue of THE LANCET highlight how the low-cost antibiotic co-trimoxazole should be given to all children with HIV in developing countries to help reduce illness and death from opportunistic infections such as pneumonia.

18 Nov 2004

Vasogen announces full patient enrollment in its trial of Celacade in peripheral arterial disease

Vasogen today announced that it has reached full enrollment in its 500-patient pivotal phase III SIMPADICO trial of Celacade (immune modulation therapy) for the treatment of peripheral arterial disease (PAD).

16 Nov 2004

Acetaminophen shows positive cardioprotective effects In heart attack, arrhythmia

Long an under-studied yet widely-used over-the-counter medication, acetaminophen over the last few years is becoming recognized for a range of potential therapeutic uses beyond headache and pain.

16 Nov 2004

Vaccine against human papillomavirus infection could reduce the global incidence of cervical cancer

A randomised trial in this week’s issue of THE LANCET shows how a vaccine against human papillomavirus (HPV) infection could potentially reduce the global incidence of cervical cancer.

14 Nov 2004

Lorus Therapeutics allowed Canadian patent to protect anticancer drugs

Lorus Therapeutics today announced that its wholly owned subsidiary, GeneSense Technologies Inc., has been allowed a patent by the Canadian Patent Office entitled "Antitumor Antisense Sequences Directed Against R1 and R2 Components of Ribonucleotide Reductase."

10 Nov 2004

Abbott's investigational anti-interleukin-12 fully human monoclonal antibody in Crohn's disease study

Results of a Phase II study of Abbott's ABT-874, a fully human anti-interleukin-12 (IL-12) monoclonal antibody, will appear tomorrow in the New England Journal of Medicine citing treatment with ABT-874 shows differences in response and remission in patients with active Crohn's disease compared to placebo, in one arm of the study.

10 Nov 2004

A new medication has dramatically reduced mortality among African-American patients suffering from heart disease

A new medication has dramatically reduced mortality among African-American patients suffering from heart disease, according to results of a study including UT Southwestern Medical Center at Dallas researchers.

9 Nov 2004

New studies demonstrate efficacy of novel Lipoxin analog in laboratory models of Crohn's disease

Berlex announced today that new laboratory results demonstrate that its modified version of the naturally occurring lipoxin molecule exerts potent anti-inflammatory and immunomodulatory effects in Crohn's disease in vivo models and may provide a promising new oral treatment.

9 Nov 2004

Zetia co-administered with Fenofibrate significantly reduced LDL ("bad") cholesterol in mixed hyperlipidemia patients

Results from a new study showed that coadministration of Zetia (ezetimibe) and fenofibrate significantly reduced LDL ("bad") cholesterol (LDL-C), non-high density lipoprotein cholesterol (non-HDL-C) and apo B1 in patients with mixed hyperlipidemia and high LDL cholesterol when compared to fenofibrate alone.

9 Nov 2004

New valve repair device that could replace major heart surgery

The Hospital of the University of Pennsylvania (HUP) is participating in a nationwide clinical trial of a new valve repair device that could replace major heart surgery in some patients.

8 Nov 2004

Patent granted for novel collagen delivery system

Hydroderm announced today that after years of clinical research, Hydroderm's exclusive Collagen Infusion Delivery System was granted a U.S. patent.

8 Nov 2004

Antidepressants may help people quit smoking when used in conjunction with nicotine patches

When used with a transdermal nicotine patch, nortriptyline—an antidepressant medication—may aid in smoking cessation, according to an article in the November 8 issue of The Archives of Internal Medicine, one of the JAMA/Archives journals.

8 Nov 2004

Lipid Sciences' selective delipidation process demonstrates enhanced ability in removing cholesterol from cells

Lipid Sciences announced today that researchers have successfully used the Company's proprietary "selective delipidation" process to create a modified form of HDL ("good cholesterol") that is known to be more effective in reverse cholesterol transport, the body's natural process for removing lipids from arterial plaque.

8 Nov 2004

Link between immune protein and longer survival in melanoma patients

Immune responses to prevent or delay the spread of melanoma, a deadly form of skin cancer, are more likely to prolong survival in patients if their immune cells carry a special kind of marker on the surface, according to a team of researchers at the University of Virginia Health System.

5 Nov 2004

Treatment to control gastroesophageal reflux disease in children found to be ineffective

According to a study published in the American Gastroenterological Association (AGA) journal Clinical Gastroenterology and Hepatology, more than 60 percent of the children who received surgical fundoplication to control gastroesophageal reflux disease (GERD) had recurring symptoms of the disease months following surgery.

4 Nov 2004

Cyclooxygenase (COX) inhibitors tested in both prevention and treatment clinical trials

Numerous compounds are examined by the National Cancer Institute (NCI) for their potential to prevent or treat cancer. One class of compounds, cyclooxygenase (COX) inhibitors, is currently being tested in both prevention and treatment clinical trials.

4 Nov 2004

Psoriasis trial enters final stage

Solbec Pharmaceuticals Ltd today announced the successful completion of the first two stages of the Phase I clinical trial of its lead compound, CoramsineTM (SBP002), for the treatment of psoriasis.

4 Nov 2004

Mad cow disease prions can be removed from blood

New research results released today confirm that infectious variant Creutzfeldt-Jakob Disease (vCJD) prions that cause the human form of "mad cow disease" can be removed from blood.

From Pall Corporation 3 Nov 2004

Studies show Pfizer's Azithromycin Microspheres effective as treatment for respiratory tract infections

Pfizer Inc.'s new investigational microsphere formulation of azithromycin, which is dosed as a one-time-only oral antibiotic, is comparable to other frequently prescribed treatments for some of the most common respiratory tract infections in adult patients.

1 Nov 2004

Efficacy News and Research

Biotoxin from puffer fish may provide treatment for opioid withdrawal

Low-cost antibiotic co-trimoxazole should be given to all children with HIV in developing countries

Vasogen announces full patient enrollment in its trial of Celacade in peripheral arterial disease

Acetaminophen shows positive cardioprotective effects In heart attack, arrhythmia

Vaccine against human papillomavirus infection could reduce the global incidence of cervical cancer

Lorus Therapeutics allowed Canadian patent to protect anticancer drugs

Abbott's investigational anti-interleukin-12 fully human monoclonal antibody in Crohn's disease study

A new medication has dramatically reduced mortality among African-American patients suffering from heart disease

New studies demonstrate efficacy of novel Lipoxin analog in laboratory models of Crohn's disease

Zetia co-administered with Fenofibrate significantly reduced LDL ("bad") cholesterol in mixed hyperlipidemia patients

New valve repair device that could replace major heart surgery

Patent granted for novel collagen delivery system

Antidepressants may help people quit smoking when used in conjunction with nicotine patches

Lipid Sciences' selective delipidation process demonstrates enhanced ability in removing cholesterol from cells

Link between immune protein and longer survival in melanoma patients

Treatment to control gastroesophageal reflux disease in children found to be ineffective

Cyclooxygenase (COX) inhibitors tested in both prevention and treatment clinical trials

Psoriasis trial enters final stage

Mad cow disease prions can be removed from blood

Studies show Pfizer's Azithromycin Microspheres effective as treatment for respiratory tract infections

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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