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Common drug for autoimmune disease may increase risk of myeloid neoplasms

Mayo Clinic researchers have found that azathioprine, a drug commonly used to treat autoimmune disease, may increase the risk of myeloid neoplasms.

3 Feb 2017

New Caltech study shows how chaperones protect ribosomal proteins

For proteins, this would be the equivalent of the red-carpet treatment: each protein belonging to the complex machinery of ribosomes -- components of the cell that produce proteins -- has its own chaperone to guide it to the right place at the right time and protect it from harm.

3 Feb 2017

Yale researchers identify new genetic defect in brain tumor cells that prevents DNA repair

In a new study, Yale Cancer Center researchers identified a novel genetic defect that prevents brain tumor cells from repairing damaged DNA.

3 Feb 2017

Majority of patients with pediatric ALL and parents over-report medication adherence, study shows

New research from the University of Alabama at Birmingham suggests that young patients with acute lymphocytic leukemia, or ALL — the most common type of pediatric cancer — and their parents are likely to report to their physician that they took more of their anti-cancer medication than they actually did.

3 Feb 2017

Study paves way for therapies against myeloid-derived suppressor cells that collude with cancer

Some cells excite the immune system. Others soothe it. Myeloid-derived suppressor cells (MDSCs) are one type of soothing cell, and previous work shows that cancer may specifically boost production of MDSCs as a way to tamp down immune response against tumors. At least that's how it works in mice.

3 Feb 2017

Patients with depression can be successful by letting go of unattainable goals,say psychologists

"If at first you don't succeed, try, try again!" This saying is drummed into us from a young age, when our tower of building blocks keeps collapsing or we just can't get the hang of riding a bicycle.

3 Feb 2017

New approach helps decide better treatment option for laryngeal cancer

Even as treatment options for laryngeal cancer seemed to improve, survival rates did not. For the most advanced patients, 50 percent survival was the norm, whether patients had surgery to totally remove the voice box or alternative treatment with chemotherapy and radiation to try to avoid surgery.

3 Feb 2017

Houston Methodist offers world's smallest heart device for patients with bradycardia

Houston Methodist Hospital is one of the first hospitals in Texas to offer the world's smallest pacemaker for patients with bradycardia, a condition characterized by a slow heart rate, usually fewer than 60 beats per minute.

2 Feb 2017

Researchers receive $2 million grant from PCORI to study effective treatment for children with KD

Kawasaki disease (KD) is an uncommon illness that affects blood vessels in the hearts of children

2 Feb 2017

UW-Madison scientists discover bone marrow proteins that regulate bone-building cells

The prospect of regenerating bone lost to cancer or trauma is a step closer to the clinic as University of Wisconsin-Madison scientists have identified two proteins found in bone marrow as key regulators of the master cells responsible for making new bone.

2 Feb 2017

Increased growth factor protects retinal blood vessels in animal models with diabetes

Researchers from the Schepens Eye Research Institute of Massachusetts Eye and Ear have shown that a slight increase in transforming growth factor beta (TGF-β), which is present in preclinical animal models with diabetic eye disease, protects retinal blood vessels from damage that commonly occurs in the early stages of the disease.

2 Feb 2017

Conventional therapies do not sufficiently treat psoriasis patients, study suggests

A substantial part of people, one in five, undergoing systemic treatment for psoriasis till have considerable problems with their disease.

2 Feb 2017

Researchers identify new mechanism that protects from bacterial infections

An international team led by the University if Barcelona has identified a new antibacterial mechanism that protects macrophages - defense cells in the immune system- from the infection of the bacteria Salmonella enterica serovar Typhimurium, a pathogen associated with several gastrointestinal diseases.

2 Feb 2017

Sphere Medical study finds high variability in glycaemic control practices across northwest European ICUs

Sphere Medical, an innovative company in critical care monitoring and diagnostics equipment, has recently presented at the Intensive Care Society State of the Art Meeting and published a scientific poster discussing, “A comparative survey of glycaemic control practice in the UK, Germany and BeNeLux”.

2 Feb 2017

Blood test that spots tumor DNA predicts survival of advanced breast cancer patients

Results of a multicenter study of 129 women with advanced breast cancer show that a blood test that spots cancer-linked DNA correctly predicted that most of those patients with higher levels of the tumor markers died significantly earlier than those with lower levels.

2 Feb 2017

People with autism see interests as possible fields of study and career paths

Adults on the autism spectrum see their interests as possible fields of study and career paths, as well as ways to mitigate anxiety, finds a study by NYU's Steinhardt School of Culture, Education, and Human Development.

2 Feb 2017

Autologous hematopoietic cell transplant may induce sustained remission of multiple sclerosis

New clinical trial results provide evidence that high-dose immunosuppressive therapy followed by transplantation of a person's own blood-forming stem cells can induce sustained remission of relapsing-remitting multiple sclerosis (MS), an autoimmune disease in which the immune system attacks the central nervous system.

2 Feb 2017

UT Southwestern scientists discover gene that protects gut from IBD

UT Southwestern Medical Center researchers have identified a gene that protects the gut from inflammatory bowel disease.

2 Feb 2017

Mayo Clinic to test vaccine for providing lifelong immunity against precancerous breast lesions

Only about 35 percent of precancerous breast lesions morph into cancer if untreated, but physicians cannot identify which lesions are potentially dangerous.

2 Feb 2017

Oral dose of phage cocktail prevents infection and cholera-like symptoms in animal model

Oral administration of a cocktail of three viruses, all of which specifically kill cholera bacteria, prevents infection and cholera-like symptoms in animal model experiments, report scientists from Tufts University School of Medicine and the Sackler School of Graduate Biomedical Sciences at Tufts in Nature Communications on Feb. 1.

1 Feb 2017

Therapy News and Research

Common drug for autoimmune disease may increase risk of myeloid neoplasms

New Caltech study shows how chaperones protect ribosomal proteins

Yale researchers identify new genetic defect in brain tumor cells that prevents DNA repair

Majority of patients with pediatric ALL and parents over-report medication adherence, study shows

Study paves way for therapies against myeloid-derived suppressor cells that collude with cancer

Patients with depression can be successful by letting go of unattainable goals,say psychologists

New approach helps decide better treatment option for laryngeal cancer

Houston Methodist offers world's smallest heart device for patients with bradycardia

Researchers receive $2 million grant from PCORI to study effective treatment for children with KD

UW-Madison scientists discover bone marrow proteins that regulate bone-building cells

Increased growth factor protects retinal blood vessels in animal models with diabetes

Conventional therapies do not sufficiently treat psoriasis patients, study suggests

Researchers identify new mechanism that protects from bacterial infections

Sphere Medical study finds high variability in glycaemic control practices across northwest European ICUs

Blood test that spots tumor DNA predicts survival of advanced breast cancer patients

People with autism see interests as possible fields of study and career paths

Autologous hematopoietic cell transplant may induce sustained remission of multiple sclerosis

UT Southwestern scientists discover gene that protects gut from IBD

Mayo Clinic to test vaccine for providing lifelong immunity against precancerous breast lesions

Oral dose of phage cocktail prevents infection and cholera-like symptoms in animal model

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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