Pharmaceuticals News and Research

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Near-infrared light used to detect signs of Alzheimer's disease

A team of researchers in Bedford, Mass. has developed a way of examining brain tissue with near-infrared light to detect signs of Alzheimer's disease.

20 Mar 2008

Natural biomedicines from the ocean

With the number of terrestrial sources that yield novel treatments for human disease decreasing year by year, the oceans have been tapped as a promising resource for discovering new natural biomedicines.

20 Mar 2008

NicOx signs agreement for commercial manufacture of Naproxcinod drug substance

NicOx S.A. (Euronext Paris: COX) has announced it has signed an agreement with the fine chemical company Archimica, for the commercial manufacturing and supply of naproxcinod drug substance (or active pharmaceutical ingredient, API).

20 Mar 2008

Neuronal regulators offer potential targets for cancer

Being too brainy can be a bad thing in a junior high cafeteria, where the social hierarchy favors other traits. "Braininess" also causes problems for cells.

20 Mar 2008

Designer enzymes

Chemists from UCLA and the University of Washington have succeeded in creating "designer enzymes," a major milestone in computational chemistry and protein engineering.

20 Mar 2008

Women's sexual disorders get medical attention in new Stanford program

Medicine is finally opening the bedroom door to women. When the male erectile dysfunction drug Viagra was approved by the U.S. Food and Drug Administration in 1998, many middle-aged men experienced a new lease on life, or at least on life in the bedroom.

19 Mar 2008

Only two per cent of 700 paediatric drug trials included independent safety checks

Only two per cent of paediatric drug trials reported that they had established independent safety monitoring committees that can help lead to the early detection of adverse drug reactions, according to a major review in the April issue of Acta Paediatrica.

19 Mar 2008

Silencing gene in tobacco plants reduces harmful carcinogens

In large-scale field trials, scientists from North Carolina State University have shown that silencing a specific gene in burley tobacco plants significantly reduces harmful carcinogens in cured tobacco leaves.

19 Mar 2008

FDA sends approvable letter for Ceftobiprole as treatment of complicated skin infections

Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (J&JPRD), has announced that it received an approvable letter from the U.S. Food and Drug Administration (FDA) regarding its New Drug Application (NDA) for ceftobiprole for the treatment of complicated skin and skin structure infections, including diabetic foot infections.

19 Mar 2008

Scientists identify potential therapy targets for schistosomiasis

A research team supported by the National Institutes of Health (NIH) Roadmap and the National Institute of Allergy and Infectious Diseases (NIAID) has identified chemical compounds that hold promise as potential therapies for schistosomiasis, a parasitic disease that afflicts more than 200 million people worldwide.

18 Mar 2008

Obese ICU patients have lower mortality but longer ICU stays

Obese intensive care patients do not have a higher ICU death rate than non-obese ICU patients, but they remain in the ICU significantly longer and are intubated significantly longer than non-obese patients, a new study has found.

18 Mar 2008

Reasonable Rx: Solving the drug price crisis

The mounting U.S. drug price crisis can be contained and eventually reversed by separating drug discovery from drug marketing and by establishing a non-profit company to oversee funding for new medicines, according to two MIT experts on the pharmaceutical industry.

18 Mar 2008

A new inhaled TB vaccine

A new tuberculosis vaccine successfully tested at the University of North Carolina at Chapel Hill is easier to administer and store and just as effective as one commonly used worldwide.

17 Mar 2008

Discovery of chemical compounds that hold promise as potential therapies for schistosomiasis

17 Mar 2008

Near-infrared light used to detect signs of Alzheimer's disease

A team of researchers in Bedford, Mass. has developed a way of examining brain tissue with near-infrared light to detect signs of Alzheimer's disease.

17 Mar 2008

Watson Pharmaceuticals files application for generic LYBREL

Watson Pharmaceuticals, Inc. has confirmed that it has filed an Abbreviated New Drug Application (ANDA) with the U.S. Food and Drug Administration (FDA) seeking approval to market its Levonorgestrel and Ethinyl Estradiol tablets, USP (0.09 mg/0.02 mg) extended-cycle oral contraceptive product prior to the expiration of patents owned by Wyeth.

14 Mar 2008

Research could put penicillin back in battle against antibiotic resistant bugs

Research led by the University of Warwick has uncovered exactly how the bacterium Streptococcus pneumoniae has become resistant to the antibiotic penicillin.

13 Mar 2008

Aerosol vaccine provides low-cost, needle-free TB treatment

A novel aerosol version of the most common tuberculosis (TB) vaccine, administered directly to the lungs as an oral mist, offers significantly better protection against the disease in experimental animals than a comparable dose of the traditional injected vaccine, researchers report this week in the Proceedings of the National Academy of Sciences.

13 Mar 2008

Aspirin/NSAID interaction in treatment for second stroke

Stroke patients who use ibuprofen for arthritis pain or other conditions while taking aspirin to reduce the risk of a second stroke undermine aspirin's ability to act as an anti-platelet agent, researchers at the University at Buffalo have shown.

13 Mar 2008

Grant expands UB/NYU study of nurses' work decisions

Keeping newly licensed nurses working in the profession is critical to solving the chronic nursing shortage experienced across the U.S., an issue nursing researchers at the University at Buffalo and New York University have been studying since 2005.

13 Mar 2008