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High paracardial fat volume linked to increased risk for heart disease in postmenopausal women

A higher volume of a certain type of fat that surrounds the heart is significantly associated with a higher risk of heart disease in women after menopause and women with lower levels of estrogen at midlife, according to new research led by the University of Pittsburgh Graduate School of Public Health.

30 Jan 2017

Breast conserving therapy better than mastectomy in early-stage breast cancer patients

Breast conserving therapy (BCT, breast conserving surgery combined with radiation therapy) is superior to mastectomy in certain types of breast cancer patients, according to results from the largest study to date, to be presented to the European Cancer Congress 2017 today.

30 Jan 2017

Onset of diabetes or rapidly deteriorating condition could be first sign of hidden pancreatic cancer

Patients and their doctors should be aware that the onset of diabetes, or a rapid deterioration in existing diabetes that requires more aggressive treatment, could be a sign of early, hidden pancreatic cancer, according to research presented at the European Cancer Congress 2017 today.

30 Jan 2017

New immunotherapy active against mucosal melanoma and improves survival for bladder cancer patients

Clinical trials of a new immunotherapy, pembrolizumab, have shown that it prolongs life significantly for patients with bladder cancer and is active against a rare sub-type of melanoma, called mucosal melanoma.

30 Jan 2017

Researchers predict melanoma death rates will decrease from current levels by 2050

By 2050 the death rates from malignant melanoma will have decreased from their current levels but the numbers of people dying from the disease will have increased due to the aging of populations.

30 Jan 2017

ACMG issues new Points to Consider statement on potential clinical application of genome editing

The American College of Medical Genetics and Genomics is weighing in on the genome editing/CRISPR debate with a new Points to Consider statement, "Genome Editing in Clinical Genetics."

29 Jan 2017

Scientists restore partial hearing and balance in deaf mice using new gene therapy

Using a novel form of gene therapy, scientists from Harvard Medical School and the Massachusetts General Hospital have managed to restore partial hearing and balance in mice born with a genetic condition that affects both.

28 Jan 2017

Orthopaedic research helps nurse recover from knee injury

Working as a bedside nurse requires extensive physical effort — pushing wheelchairs and beds, twisting and lifting, and long periods on your feet.

28 Jan 2017

Tiny transport vesicles and shifts in metabolism can signal big changes in cancer tissues

Microscopic shifts in metabolism and increases in tiny transport vesicles out of tumor cells preface larger changes to the tumor environment and could prepare the way for cancerous cells to spread and metastasize, University of Illinois researchers report.

28 Jan 2017

Psychosomatic research findings may provide insights into unexplained and difficult to treat disorders

In the current issue of Psychotherapy and Psychosomatic Dr. Giovanni A. Fava and collaborators describe research findings that may shed new light on unexplained and difficult to treat medical disorders.

28 Jan 2017

Hypoxia in primary tumors influences dormant DTCs that evade cancer therapy, study shows

In a first of its kind study, Mount Sinai researchers have discovered the conditions by which specific signals in primary tumors of head and neck and breast cancers, pre-program cancer cells to become dormant and evade chemotherapy after spreading.

28 Jan 2017

GUMC researchers describe lab technique to fill gaps in clinical care and research

Researchers who developed and tested a revolutionary laboratory technique that allows for the endless growth of normal and diseased cells in a laboratory are publicly sharing how the technique works.

28 Jan 2017

New MIP system for therapeutic gene delivery can enhance transgene expression using AAV vector

Advanced engineering of a mini-intronic plasmid (MIP) system designed to carry a therapeutic gene can significantly enhance the expression of the transgene delivered using an adeno-associated viral (AAV) vector.

28 Jan 2017

Single-molecule compounds may become basis for new antioxidant therapies

Treated particles of graphene derived from carbon nanotubes have demonstrated remarkable potential as life-saving antioxidants, but as small as they are, something even smaller had to be created to figure out why they work so well.

28 Jan 2017

Both accelerator and brake in the brain control all types of movements, research shows

In order to drive a car, you need a good balance between accelerator and brake. The same applies to a part of the brain - the striatum - that controls our movements.

28 Jan 2017

UAB researchers find how gut fails to prevent HIV-1 infection

The barrier between the gut and the bloodstream is severely damaged in the first few weeks of infection by HIV-1 virus.

28 Jan 2017

Oral devices improve sleep in OSA patients but may not reduce key heart disease risk factors

In patients with severe obstructive sleep apnea (OSA), oral appliances that treat the condition by moving the lower jaw forward appear to improve sleep but not reduce key risk factors for developing heart and other cardiovascular disease, according to new research published online, ahead of print in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

28 Jan 2017

Hemodialysis patients do not wish to receive treatment for depression, study shows

Many patients with kidney failure who are receiving chronic hemodialysis have depressive symptoms but do not wish to receive aggressive treatment to alleviate them, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology.

28 Jan 2017

Joslin scientists suggest new approach to improve stroke therapy

The standard of care for treating strokes caused by blood clots involves the therapeutic infusion of tissue plasminogen activator (tPA), which can help to dissolve the clots and restore blood flow.

27 Jan 2017

Bacterial by-product helps correct gut microbiome imbalance in mouse model of ALS

A bacterial by-product known to be important in maintaining gut health may slow the progression of amyotrophic lateral sclerosis, or ALS - a progressive, neurodegenerative disease.

27 Jan 2017

Therapy News and Research

High paracardial fat volume linked to increased risk for heart disease in postmenopausal women

Breast conserving therapy better than mastectomy in early-stage breast cancer patients

Onset of diabetes or rapidly deteriorating condition could be first sign of hidden pancreatic cancer

New immunotherapy active against mucosal melanoma and improves survival for bladder cancer patients

Researchers predict melanoma death rates will decrease from current levels by 2050

ACMG issues new Points to Consider statement on potential clinical application of genome editing

Scientists restore partial hearing and balance in deaf mice using new gene therapy

Orthopaedic research helps nurse recover from knee injury

Tiny transport vesicles and shifts in metabolism can signal big changes in cancer tissues

Psychosomatic research findings may provide insights into unexplained and difficult to treat disorders

Hypoxia in primary tumors influences dormant DTCs that evade cancer therapy, study shows

GUMC researchers describe lab technique to fill gaps in clinical care and research

New MIP system for therapeutic gene delivery can enhance transgene expression using AAV vector

Single-molecule compounds may become basis for new antioxidant therapies

Both accelerator and brake in the brain control all types of movements, research shows

UAB researchers find how gut fails to prevent HIV-1 infection

Oral devices improve sleep in OSA patients but may not reduce key heart disease risk factors

Hemodialysis patients do not wish to receive treatment for depression, study shows

Joslin scientists suggest new approach to improve stroke therapy

Bacterial by-product helps correct gut microbiome imbalance in mouse model of ALS

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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