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Researchers start enrolling patients for Phase II gene therapy trial for choroideremia

Following on from a successful world’s first Phase I gene therapy trial for choroideremia, Professor Robert MacLaren and his team at Oxford University and the Oxford Eye Hospital at the John Radcliffe Hospital have started a Phase II trial enrolling 30 patients.

11 Nov 2016

New study identifies novel target for treatment of Graves' disease and other scarring eye conditions

A new class of therapies may be on the horizon for thyroid eye disease (TED) and other destructive scarring conditions.

11 Nov 2016

Researchers propose model photomotors for rapid nanoparticle transport

Scientists from the Moscow Institute of Physics and Technology, Semenov Institute of Chemical Physics of the Russian Academy of Sciences, and Chuiko Institute of Surface Chemistry of the National Academy of Sciences of Ukraine have proposed a model nanosized dipole photomotor based on the phenomenon of light-induced charge redistribution.

11 Nov 2016

CHLA researchers receive TRP grant to study new way of combating relapsed ALL

Yong-Mi Kim, MD, PhD, of The Saban Research Institute of Children's Hospital Los Angeles, has been awarded a 3 year translational research program grant from the Leukemia & Lymphoma Society to study a novel approach to eradicating minimal residual disease in patients with acute lymphoblastic leukemia (ALL).

10 Nov 2016

Statistical analysis reveals possible scientific misconduct in some bone health studies

A new study suggests probable scientific misconduct in at least some of 33 bone health trials published in various medical journals.

10 Nov 2016

Scientists identify genetic mutations in highly aggressive rhabdoid meningiomas

Meningiomas are the most common primary brain tumors, but the term encompasses over a dozen subtypes that range from benign to highly aggressive.

10 Nov 2016

Adolescent obesity contributes to endometrial cancer risk in women

While it is well established that obesity is closely linked to endometrial cancer risk, most past findings have only looked at risk in relation to one measure of body size at a time.

10 Nov 2016

Mild postoperative pulmonary complications linked to increased mortality risk

Researchers at the University of Colorado Anschutz Medical Campus, along with seven other major institutions, have found that even mild postoperative pulmonary complications (PPCs) are significantly associated with increased death within the first week after surgery.

10 Nov 2016

Broadly neutralizing antibody delays return of viral rebound in HIV-1 infected individuals

The administration of VRC01, a potent and broadly neutralizing HIV-specific antibody, is safe, is well-tolerated, generated high plasma concentrations and modestly delayed the return of HIV viral rebound in HIV-1 infected individuals after they stopped receiving antiretroviral therapy, according to a study published in the New England Journal of Medicine by researchers at the University of Alabama at Birmingham, the National Institutes of Health and the University of Pennsylvania Penn Center for AIDS Research.

10 Nov 2016

Research offers new insights into how immunotherapy could help treat or functionally cure HIV

Immunotherapy has revolutionized treatment options in oncology, neurology, and many infectious diseases and now there is fresh hope that the same method could be used to treat or functionally cure HIV, according to two related studies from Perelman School of Medicine at the University of Pennsylvania, the University of Alabama at Birmingham, and the National Institutes of Health.

9 Nov 2016

Experimental vaccine/immune stimulant combination may lead to viral remission in HIV patients

A study led by researchers at Beth Israel Deaconess Medical Center, in collaboration with scientists at Walter Reed Army Institute of Research, Janssen Vaccines & Prevention B.V., one of the Janssen Pharmaceutical Companies of Johnson & Johnson and Gilead Sciences, Inc., has demonstrated that combining an experimental vaccine with an innate immune stimulant may help lead to viral remission in people living with HIV.

9 Nov 2016

Ludwig study shows how experimental drug can reverse effects of suppressive immune cells

A Ludwig Cancer Research study shows that an experimental drug currently in clinical trials can reverse the effects of troublesome cells that prevent the body's immune system from attacking tumors.

9 Nov 2016

Investigational treatment combination improves virologic control in SIV-infected monkeys

Researchers have found that an investigational treatment combination of a therapeutic vaccine and an immune-stimulator improves virologic control and delays viral rebound following the discontinuation of antiretroviral therapy (ART) in non-human primates infected with SIV, the simian form of HIV.

9 Nov 2016

Therapy News and Research

Researchers start enrolling patients for Phase II gene therapy trial for choroideremia

New study identifies novel target for treatment of Graves' disease and other scarring eye conditions

Researchers propose model photomotors for rapid nanoparticle transport

CHLA researchers receive TRP grant to study new way of combating relapsed ALL

Statistical analysis reveals possible scientific misconduct in some bone health studies

Scientists identify genetic mutations in highly aggressive rhabdoid meningiomas

Adolescent obesity contributes to endometrial cancer risk in women

Mild postoperative pulmonary complications linked to increased mortality risk

Broadly neutralizing antibody delays return of viral rebound in HIV-1 infected individuals

Research offers new insights into how immunotherapy could help treat or functionally cure HIV

Experimental vaccine/immune stimulant combination may lead to viral remission in HIV patients

Ludwig study shows how experimental drug can reverse effects of suppressive immune cells

Investigational treatment combination improves virologic control in SIV-infected monkeys

High-intensity statin treatments increase survival rates in patients with cardiovascular disease

Novel sensor can quantify effects of radiation on individual cancer cells

Using urine samples to diagnose disease in preterm newborns

Scientists find new way to bypass bowel cancer's defence against treatment

Weight loss condition provides clues to why cancer immunotherapy may fail in many patients

UTHealth study receives $1.9 million NIH grant to identify effective treatment for cocaine addiction

New research explains how tumors may impair ability of the liver to respond to caloric deprivation

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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