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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

New bioinformatics platform predicts optimal treatment combinations for cancer patients

Researchers at The University of Texas MD Anderson Cancer Center have developed a new bioinformatics platform that predicts optimal treatment combinations for a given group of patients based on co-occurring tumor alterations.

12 Apr 2022

Thoracic aortic diameter serves as a biomarker for major cardiovascular events

The diameter of the thoracic aorta is a biomarker for heart attacks and other adverse cardiovascular events in women and men, according to a new study published in the journal Radiology.

12 Apr 2022

Children born in exceptionally long-lived families have reduced risk for developing type II diabetes

What makes some people predisposed to live and remain healthy much longer than others? That some persons reach an exceptional age has been recorded throughout history.

11 Apr 2022

Safety profile of colchicine in COVID-19 patients

Researchers evaluated the use of colchicine in COVID-19 patients.

11 Apr 2022

NSCLC patients treated with KRAS G12C inhibitor sotorasib may receive long-term clinical benefit

Patients with non-small cell lung cancer (NSCLC) treated with the KRAS G12C inhibitor sotorasib (Lumakras) had a two-year overall survival rate of 32.5 percent, according to data from the CodeBreaK 100 clinical trial presented during the AACR Annual Meeting 2022, held April 8-13.

10 Apr 2022

ADDF supports the need to gather more evidence about clinical effectiveness of anti-amyloid drug

On Thursday, April 7, the Centers for Medicare and Medicaid (CMS) formalized its plan to cover the anti-amyloid drug Aduhelm only for patients enrolled in clinical trials.

8 Apr 2022

Exploring SARS-CoV-2 detection by profiling micro RNAs

A new study analyzed the micro ribonucleic acid profiles in nasal swabs collected from COVID-19 patients.

8 Apr 2022

Insights into the pathophysiology of NeuroCOVID

A new study describes the neurological features of COVID-19, both short- and long-term.

6 Apr 2022

New technique can reliably identify patients most likely to suffer post-surgery pain

Patients who are most likely to suffer severe pain following an operation can be reliably identified using a new technique developed at the University of Birmingham.

5 Apr 2022

Phenotypic changes in monocytes from COVID-19 patients

Researchers investigate monocytes to better understand how infection with SARS-CoV-2 can cause dysfunction in these immune cells.

5 Apr 2022

Do androgens play a role in COVID-19 severity?

Researchers assess the association between the AR polyQ polymorphism with COVID-19 severity using a large cohort of 1,136 COVID-19 male patients.

5 Apr 2022

Combining two biomarkers could help identify patients with subcortical small-vessel disease

In recent years, subcortical small-vessel disease has become an increasingly common cognitive diagnosis.

5 Apr 2022

EMA issues qualification opinion for islet autoantibodies as enrichment biomarkers for T1D prevention trials

Critical Path Institute's Type 1 Diabetes Consortium (T1DC) today announced that the European Medicines Agency has issued a positive qualification opinion for pancreatic islet autoantibodies as enrichment biomarkers for type 1 diabetes (T1D) prevention trials.

5 Apr 2022

Study generates a picture of the myocardial transcriptional landscape of COVID-19

Researchers profiled cardiac tissue transcriptomes of COVID-19 patients.

5 Apr 2022

Proteins in saliva strongly associated with the diagnosis of severe COVID-19

Researchers have identified a family of proteins that is significantly elevated in the saliva of patients hospitalized with COVID-19.

4 Apr 2022

Researchers use breast milk to identify new set of protein biomarkers for cancer

A simple blood test for women of all ages and risk levels could one day be possible thanks to a new set of protein biomarkers that researchers identified using breast milk.

4 Apr 2022

Experimental siRNA therapeutic shows promise to reduce an important driver of heart disease risk

While there are effective therapies to reduce the risk of heart disease by lowering low-density lipoprotein (LDL), or "bad" cholesterol, and other lipids, to date there are no approved treatments to lower lipoprotein(a), a lesser-known driver of heart disease risk.

3 Apr 2022

New drug shows promise in relieving symptoms associated with hypertrophic cardiomyopathy

A new drug shows promise in providing relief to cardiomyopathy patients experiencing shortness of breath, according to late-breaking research presented today at the American College of Cardiology (ACC) Scientific Session in Washington, D.C.

3 Apr 2022

Scientists develop a novel measure of delirium severity

Delirium is a serious change in brain function that affects up to 64 percent of older medical patients and up to 50 percent of older surgical patients.

31 Mar 2022

$4 million program launched to find transformative therapies for ADNP syndrome

Researchers at the UC Davis MIND Institute are launching a $4 million program to find transformative therapies for ADNP syndrome. The rare genetic condition causes developmental delays and can affect the brain, heart, gastrointestinal system and more.

29 Mar 2022

Biomarker News and Research

Further Reading

New bioinformatics platform predicts optimal treatment combinations for cancer patients

Thoracic aortic diameter serves as a biomarker for major cardiovascular events

Children born in exceptionally long-lived families have reduced risk for developing type II diabetes

Safety profile of colchicine in COVID-19 patients

NSCLC patients treated with KRAS G12C inhibitor sotorasib may receive long-term clinical benefit

ADDF supports the need to gather more evidence about clinical effectiveness of anti-amyloid drug

Exploring SARS-CoV-2 detection by profiling micro RNAs

Insights into the pathophysiology of NeuroCOVID

New technique can reliably identify patients most likely to suffer post-surgery pain

Phenotypic changes in monocytes from COVID-19 patients

Do androgens play a role in COVID-19 severity?

Combining two biomarkers could help identify patients with subcortical small-vessel disease

EMA issues qualification opinion for islet autoantibodies as enrichment biomarkers for T1D prevention trials

Study generates a picture of the myocardial transcriptional landscape of COVID-19

Proteins in saliva strongly associated with the diagnosis of severe COVID-19

Researchers use breast milk to identify new set of protein biomarkers for cancer

Experimental siRNA therapeutic shows promise to reduce an important driver of heart disease risk

New drug shows promise in relieving symptoms associated with hypertrophic cardiomyopathy

Scientists develop a novel measure of delirium severity

$4 million program launched to find transformative therapies for ADNP syndrome

Event guide: World Clinical Biomarkers & CDx Summit Japan eBook

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