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Breakthrough study links NSD2 gene to plasma cell identity in myeloma

A new research paper was published in Oncotarget, Volume 16, on March 21, 2025, titled "NSD2-epigenomic reprogramming and maintenance of plasma cell phenotype in t(4;14) myeloma."

2 Apr 2025

New class of antibiotic selectively targets gonorrhea bacterium

Researchers from the universities in Konstanz and Vienna discover a new class of antibiotic that selectively targets Neisseria gonorrhoeae, the bacterium that causes gonorrhea.

2 Apr 2025

AI predicts bacterial resistance to antibiotics with high accuracy

An AI model trained on large amounts of genetic data can predict whether bacteria will become antibiotic-resistant.

2 Apr 2025

ICRAFT platform identifies new targets for cancer immunotherapy

Professor Zeng Zexian's team from the Center for Quantitative Biology at the Peking University Academy for Advanced Interdisciplinary Studies, in collaboration with the Peking University-Tsinghua University Joint Center for Life Sciences, has developed ICRAFT, an innovative computational platform for identifying cancer immunotherapy targets.

1 Apr 2025

New approach speeds up personalized cancer treatment for young patients

A pan-Canadian team has developed a new way to quickly find personalized treatments for young cancer patients, by growing their tumors in chicken eggs and analyzing their proteins.

1 Apr 2025

Scientists discover key genes for regenerating cells in the ear and eye

The same genes could hold the key to regenerating cells in the ear and eye, according to a new mouse study from the USC Stem Cell laboratory of Ksenia Gnedeva, PhD, published in the Proceedings of the National Academy of Sciences (PNAS).

1 Apr 2025

Long-term Transcendental Meditation shown to improve stress and aging markers

A collaborative study conducted by researchers at Maharishi International University (MIU), the University of Siegen, and the Uniformed Services University of the Health Sciences reveals that individuals practicing Transcendental Meditation (TM) technologies long-term show favorable biological markers of aging and stress.

31 Mar 2025

Swedish researchers identify genetic variants linked to atherosclerosis

Swedish researchers have identified genetic variants that increase the risk of atherosclerosis. The aim is for these new findings to enable earlier detection of atherosclerosis and improved treatment of cardiovascular diseases such as heart attack and stroke.

31 Mar 2025

Traditional Chinese medicine targets cholesterol metabolism for cancer treatment

Researchers explore how natural compounds in traditional Chinese medicine can modulate cholesterol metabolism to combat cancer.

31 Mar 2025

Studies explore bioactive compounds in plants for disease prevention

Fruits and plant extracts contain bioactive compounds that can help treat or prevent diseases. To characterize and understand their mechanism of action, researchers from universities and research institutions in Brazil and Germany have conducted independent but complementary studies.

28 Mar 2025

Research sheds light on the genetic basis of music enjoyment

Music is central to human emotion and culture. Does our ability to enjoy music have a biological basis? A genetic twin study, published in Nature Communications, shows that music enjoyment is partly heritable.

28 Mar 2025

Scientists develop lab model to study TDP-43 accumulation in neurodegeneration

Accumulation of a protein called TDP-43 is a key feature of ALS and frontotemporal dementia. In a newly published study, researchers report 'seeding' this accumulation through fragments of the culprit protein created in the lab.

28 Mar 2025

Research provides a comprehensive genomic and epigenomic landscape of ICE syndrome

Iridocorneal endothelial (ICE) syndrome is a rare, irreversibly blinding ocular disorder with an unknown etiology. Lack of targeted effective drugs, inadequate disease prognosis, and high relapse rates post-surgery are the current challenges of ICE.

28 Mar 2025

AI-powered model improves prediction of bladder cancer treatment outcomes

Leveraging the power of AI and machine learning technologies, researchers at Weill Cornell Medicine developed a more effective model for predicting how patients with muscle-invasive bladder cancer will respond to chemotherapy.

28 Mar 2025

Pharmacogenomic testing could help reduce adverse drug reactions in the UK

A new study from Queen Mary University of London found that 9% of all reported adverse drug reactions (ADRs) reported to the UK medicines regulator are associated with medications where side effect risk is partly dependent on patient's genes.

27 Mar 2025

Digital PCR can reliably quantify stable deep molecular remission of chronic myeloid leukemia

Researchers have found that the clinical application of BCR::ABL1 digital PCR can reliably quantify stable deep molecular remission of chronic myeloid leukemia (CML), which will help to determine for which patients chronic drug treatment could potentially be discontinued.

27 Mar 2025

Understanding the roles of NOTCH signaling in cancer resistance

Cancer remains a leading cause of death globally, with lung cancer being particularly lethal. Despite advancements in diagnostics and therapies, the five-year survival rates for advanced tumors have seen minimal improvement, largely due to therapeutic resistance.

27 Mar 2025

Study sheds new light on the mechanisms underlying head and neck cancer metastasis

A recent study published in Engineering has shed new light on the mechanisms underlying the metastasis of head and neck squamous cell carcinoma (HNSCC). The research identified enolase 2 (ENO2), a crucial glycolytic enzyme, as a significant factor associated with lymphatic metastasis in HNSCC.

27 Mar 2025

New research sheds light on prostate cancer resistance mechanisms

According to the American Cancer Society, approximately 1 in 8 men in the U.S. will be diagnosed with prostate cancer during their lifetime.

27 Mar 2025

Study explores how sex chromosomes and hormones influence immune responses

Women have a higher proportion of key immune cells between puberty and menopause, which may be linked to the sex hormone estrogen and explain why they are less susceptible to certain infectious diseases than men, according to a new study led by researchers at UCL.

27 Mar 2025