Infectious Diseases News and Research

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Exploring immunogenicity, boosting efficacy and safety of modified vaccinia Ankara-Bavarian Nordic vaccine

Researchers evaluated the immunogenicity, boosting efficacy, and safety of single-dose and two-dose MVA-BN (modified vaccinia Ankara-Bavarian Nordic) vaccinations in comparison to replicating smallpox vaccines.

7 Dec 2022

Laos malaria outbreak in 2020–21 likely caused by multidrug-resistant strains of P. falciparum

Researchers describe the genetic epidemiology and dynamics of the Plasmodium falciparum responsible for malaria outbreaks in Attapeu Province, Laos.

5 Dec 2022

Much of the CDC is working remotely. That could make changing the agency difficult.

Earlier this year, top leadership at the Centers for Disease Control and Prevention began a monumental task: turning the sprawling, labyrinthine organization known for its highly specialized, academically focused scientific research into a sleek, flexible public health response agency primed to serve the American public.

5 Dec 2022

Trial shows acoziborole drug clears body of African sleeping sickness parasites

Researchers evaluate the efficacy and safety of an oral antimicrobial drug acoziborole in patients with human African trypanosomiasis.

4 Dec 2022

Researchers develop potent yet low-inflammatory mRNA cancer vaccine vectors

Lipid nanoparticle (LNP)-based messenger ribonucleic acid (mRNA) vaccines have recently emerged as a promising strategy for the prevention and treatment of cancers, as well as infectious diseases.

4 Dec 2022

The business of clinical trials is booming. Private equity has taken notice.

After finding success investing in the more obviously lucrative corners of American medicine — like surgery centers and dermatology practices — private equity firms have moved aggressively into the industry's more hidden niches: They are pouring billions into the business of clinical drug trials.

2 Dec 2022

Best practices and challenges in One Health approach to fight zoonotic diseases

Announcing a new article publication for Zoonoses journal. Zoonoses are infectious diseases that can be transmitted from animals to humans and/or from humans to animals.

1 Dec 2022

Prior infection and vaccination protects against severe outcomes from SARS-CoV-2 Omicron infection

Previous infection with SARS-CoV-2 and booster vaccination protect against ICU admission and mortality following infection with the Omicron variant.

1 Dec 2022

New metagenomic study reveals global landscape of antimicrobial resistance

There are large geographical differences in both how frequently resistant genes occur and in which types of bacteria the genes are found.

1 Dec 2022

The Elton John AIDS Foundation: a powerful force in the end to the AIDS epidemic

To commemorate World AIDS Day, News Medical spoke to Anne Aslett, Chief Executive Officer of the Elton John AIDS Foundation, about the work of the foundation and the actions required to address inequalities and help end AIDS.

1 Dec 2022

Study provides a framework to guide the development of variant-resistant SARS-CoV-2 vaccines

Latest research findings show that vaccine-elicited neutralizing antibodies against SARS-CoV-2 are mostly directed against one of the two main domains of the viral entry machinery.

30 Nov 2022

SARS-CoV-2 can cause hyperglycemia in cats

In a recent study published in The Journal of Infectious Diseases, researchers explored the association between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and hyperglycemia in cats.

30 Nov 2022

Severe undernutrition increases risk of unfavorable outcomes for individuals undergoing TB treatment

In 2021, an estimated 10.6 million individuals developed tuberculosis (TB) and 1.6 million died, making it the second most lethal infection in the world after SARS-CoV-2.

30 Nov 2022

Phase 2/3 clinical trial shows that Clover’s vaccine candidate reduces household transmission of SARS-CoV-2

Clover Biopharmaceuticals, Ltd., a global clinical-stage biotechnology company developing novel vaccines and biologic therapeutics, and the International Vaccine Institute, an international nonprofit organization devoted to providing vaccines critical to global public health and based in Seoul, Korea, today announced that Clinical Infectious Diseases has published additional data from SPECTRA, a global Phase 2/3 clinical trial, that showed vaccination with SCB-2019 (CpG 1018/Alum) reduced the risk of transmitting SARS-CoV-2 infection to household members, compared to placebo participants.

30 Nov 2022

Researchers receive $3 million-plus NIH grant to develop treatment for drug-resistant fungus

With a new $3 million-plus grant from the National Institutes of Health (NIH), Case Western Reserve University researchers are examining the next level of treatment for Candida auris (C.auris), a multidrug-resistant yeast that causes serious infection and, in some cases, death.

30 Nov 2022

Australian researchers unearth a new form of antimicrobial resistance

Australian researchers have uncovered a new form of antimicrobial resistance (AMR) – undetectable using traditional laboratory testing methods – in a discovery set to challenge existing efforts to monitor and tackle one of the world's greatest health threats.

30 Nov 2022

Study shows the efficacy of new, single-dose, oral treatment for sleeping sickness

A new, single-dose, oral treatment for sleeping sickness is as effective as current treatments and could be a key factor in eliminating disease transmission by 2030, suggests a new study published in The Lancet Infectious Diseases.

30 Nov 2022

Pregnant people can safely take Paxlovid to reduce the possibility of severe COVID-19, study shows

Findings from a Johns Hopkins Medicine research study published today in JAMA Network Open provide strong evidence that people who are pregnant and have been infected with SARS-CoV-2 (the virus that causes COVID-19) can safely take the antiviral drug Paxlovid to reduce the possibility of severe disease.

29 Nov 2022

Plant-based foods vs. animal-based foods

An editorial published in The American Journal of Cardiology describes how wrong food choices can impact health at individual and population levels. Also discussed in the editorial are the ethical implications of eating animal-based foods and measures to promote healthier diets.

29 Nov 2022

Powerful imaging tool creates 3D atlas of the spectrum of tuberculous and COVID-19 lung lesions

Gross anatomy reveals three-dimensional shapes of pathology at a large scale. Histology, in contrast, reveals the microscopic anatomy of biological structures. But that magnification comes at a cost - histology shows only two-dimensional shapes because it studies small, flat slices of stained tissue.

29 Nov 2022

Infectious Diseases News and Research

Exploring immunogenicity, boosting efficacy and safety of modified vaccinia Ankara-Bavarian Nordic vaccine

Laos malaria outbreak in 2020–21 likely caused by multidrug-resistant strains of P. falciparum

Much of the CDC is working remotely. That could make changing the agency difficult.

Trial shows acoziborole drug clears body of African sleeping sickness parasites

Researchers develop potent yet low-inflammatory mRNA cancer vaccine vectors

The business of clinical trials is booming. Private equity has taken notice.

Best practices and challenges in One Health approach to fight zoonotic diseases

Prior infection and vaccination protects against severe outcomes from SARS-CoV-2 Omicron infection

New metagenomic study reveals global landscape of antimicrobial resistance

The Elton John AIDS Foundation: a powerful force in the end to the AIDS epidemic

Study provides a framework to guide the development of variant-resistant SARS-CoV-2 vaccines

SARS-CoV-2 can cause hyperglycemia in cats

Severe undernutrition increases risk of unfavorable outcomes for individuals undergoing TB treatment

Phase 2/3 clinical trial shows that Clover’s vaccine candidate reduces household transmission of SARS-CoV-2

Researchers receive $3 million-plus NIH grant to develop treatment for drug-resistant fungus

Australian researchers unearth a new form of antimicrobial resistance

Study shows the efficacy of new, single-dose, oral treatment for sleeping sickness

Pregnant people can safely take Paxlovid to reduce the possibility of severe COVID-19, study shows

Plant-based foods vs. animal-based foods

Powerful imaging tool creates 3D atlas of the spectrum of tuberculous and COVID-19 lung lesions

Industry Focus eBook - Infectious Diseases (3rd Edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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