Oxidative Stress News and Research

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Oxidative Stress is a condition in which antioxidant levels are lower than normal. Antioxidant levels are usually measured in blood plasma.

Reciprocal communication between different cell types contributes to neuronal integrity

Researchers at Johannes Gutenberg University Mainz have discovered a new form of communication between different cell types in the brain. Nerve cells interact with neighboring glial cells, which results in a transfer of protein and genetic information. Nerve cells are thus protected against stressful growth conditions.

16 Jul 2013

Alize Pharma initiates AZP-531 Phase I clinical trial for treatment of type 2 diabetes

Alize Pharma, a company specialized in the development of drugs for the treatment of metabolic diseases and rare diseases, announces today the launch of the first Phase I clinical trial for AZP-531, its unacylated ghrelin analog, in type 2 diabetes.

16 Jul 2013

Scientists discover how BRCA1 gene mutations predispose women to breast and ovarian cancers

Scientists led by Drs. Mona Gauthier and Tak Mak at The Campbell Family Institute for Breast Cancer Research at the Princess Margaret Cancer Centre have solved a key piece in the puzzle of how BRCA1 gene mutations specifically predispose women to breast and ovarian cancers.

16 Jul 2013

Scientists uncover easy strategies to prevent harmful side-effects of antibiotics responses

A team of scientists at the Wyss Institute for Biologically Inspired Engineering at Harvard University has discovered why long-term treatment with many common antibiotics can cause harmful side effects-and they have uncovered two easy strategies that could help prevent these dangerous responses.

4 Jul 2013

Researchers identify biological roots of migraine from large-scale genome study

In the largest study of migraines, researchers have found 5 genetic regions that for the first time have been linked to the onset of migraine. This study opens new doors to understanding the cause and biological triggers that underlie migraine attacks.

24 Jun 2013

Researchers uncover DNA damage checkpoint used by cells to monitor oxidatively damaged DNA

In current health lore, antioxidants are all the rage, as "everybody knows" that reducing the amount of "reactive oxygen species" -- cell-damaging molecules that are byproducts of cellular metabolism -- is critical to staying healthy. What everyone doesn't know is that our bodies already have a complex set of processes built into our cells that handle these harmful byproducts of living and repair the damage they cause.

15 Jun 2013

Drug used to control Type II diabetes can help repair spinal cords of mice suffering from inherited disease

A drug used to control Type II diabetes can help repair the spinal cords of mice suffering from the inherited disease adrenoleukodystrophy which, untreated, leads eventually to a paralysis, a vegetative state and death.

10 Jun 2013

New research shows uremic toxins increase heart attack risk

MD-Patients with advanced kidney disease who are undergoing hemodialysis are known to be highly susceptible to heart attacks and other cardiovascular complications, and now scientists likely know why.

31 May 2013

Patented nicotinamide riboside launched by Chromadex

ChromaDex Corporation, an innovative natural products company that provides proprietary, science-based solutions and ingredients to the dietary supplement, food & beverage, animal health, cosmetic and pharmaceutical industries, announced today the launch of NIAGEN, its novel, patented, branded nicotinamide riboside.

29 May 2013

More evidence of high oxidative stress levels found in Down syndrome neurons

Down syndrome, the most common genetic form of intellectual disability, results from an extra copy of one chromosome. Although people with Down syndrome experience intellectual difficulties and other problems, scientists have had trouble identifying why that extra chromosome causes such widespread effects.

28 May 2013

Cinnamon compounds show some promise in the effort to fight Alzheimer's disease

Cinnamon: Can the red-brown spice with the unmistakable fragrance and variety of uses offer an important benefit? The common baking spice might hold the key to delaying the onset of -- or warding off -- the effects of Alzheimer's disease.

24 May 2013

Groundbreaking anti-aging dietary supplement

Jeunesse Global, a network marketing company that dedicates its research to promoting healthy and youthful living, has produced the solution to one of the fundamental causes of cellular aging.

23 May 2013

Long-term depression linked with life-threatening chronic disease, earlier death

The first symptoms of major depression may be behavioral, but the common mental illness is based in biology — and not limited to the brain. In recent years some studies have linked major, long-term depression with life-threatening chronic disease and with earlier death, even after lifestyle risk factors have been taken into account.

23 May 2013

Dietary exposure to certain plastics may cause metabolic and hormonal abnormalities in children

Plastic additives known as phthalates (pronounced THAL-ates) are odorless, colorless and just about everywhere: They turn up in flooring, plastic cups, beach balls, plastic wrap, intravenous tubing and-according to the Centers for Disease Control and Prevention-the bodies of most Americans.

22 May 2013

Study shows PDH enzyme plays a major role in regulation of oncogene-induced cellular senescence

An article published on the journal Nature describes the major role that Pyruvate dehydrogenase (PDH) —an enzyme of cellular energy metabolism— plays in the regulation of the cellular senescence induced by the oncogene BRAF, which usually appears mutated in melanoma and other cancers.

22 May 2013

Kinase inhibitors: an interview with Jan Hoflack, CSO of Oncodesign

Kinase inhibitors are molecules that block the activity of kinases. Kinases are a specific class of enzymes. They are extremely important in signal transduction processes in the human body meaning that they actually regulate most of the physiological processes that take place in the body.

7 May 2013

Research suggests loss of skin or hair color can be corrected by a new compound, pseudocatalase

Hair dye manufacturers are on notice: The cure for gray hair is coming. That's right, the need to cover up one of the classic signs of aging with chemical pigments will be a thing of the past thanks to a team of European researchers.

6 May 2013

Oxygenation targets and outcomes in premature infants

In a randomized trial performed to help resolve the uncertainty about the optimal oxygen saturation therapy in extremely preterm infants, researchers found that targeting saturations of 85 percent to 89 percent compared with 91 percent to 95 percent had no significant effect on the rate of death or disability at 18 months, according to a study published by JAMA. The study is being released early online to coincide with its presentation at the Pediatric Academic Societies annual meeting.

6 May 2013

NIH-funded study uncovers novel way that grapes exert beneficial effects in the heart

A study appearing in the Journal of Nutritional Biochemistry- demonstrates that grapes are able to reduce heart failure associated with chronic high blood pressure (hypertension) by increasing the activity of several genes responsible for antioxidant defense in the heart tissue.

3 May 2013

Intermittent fasting: A path to weight loss and improved cardiovascular risk

Intermittent fasting is all the rage, but scientific evidence showing how such regimes affect human health is not always clear cut. Now a scientific review in the British Journal of Diabetes and Vascular Disease published by SAGE, suggests that fasting diets may help those with diabetes and cardiovascular disease, alongside established weight loss claims.

29 Apr 2013

Oxidative Stress News and Research

Further Reading

Reciprocal communication between different cell types contributes to neuronal integrity

Alize Pharma initiates AZP-531 Phase I clinical trial for treatment of type 2 diabetes

Scientists discover how BRCA1 gene mutations predispose women to breast and ovarian cancers

Scientists uncover easy strategies to prevent harmful side-effects of antibiotics responses

Researchers identify biological roots of migraine from large-scale genome study

Researchers uncover DNA damage checkpoint used by cells to monitor oxidatively damaged DNA

Drug used to control Type II diabetes can help repair spinal cords of mice suffering from inherited disease

New research shows uremic toxins increase heart attack risk

Patented nicotinamide riboside launched by Chromadex

More evidence of high oxidative stress levels found in Down syndrome neurons

Cinnamon compounds show some promise in the effort to fight Alzheimer's disease

Groundbreaking anti-aging dietary supplement

Long-term depression linked with life-threatening chronic disease, earlier death

Dietary exposure to certain plastics may cause metabolic and hormonal abnormalities in children

Study shows PDH enzyme plays a major role in regulation of oncogene-induced cellular senescence

Kinase inhibitors: an interview with Jan Hoflack, CSO of Oncodesign

Research suggests loss of skin or hair color can be corrected by a new compound, pseudocatalase

Oxygenation targets and outcomes in premature infants

NIH-funded study uncovers novel way that grapes exert beneficial effects in the heart

Intermittent fasting: A path to weight loss and improved cardiovascular risk

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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